Dynamic regulation

Ebook "Epigenetics in cardiac disease" describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an overview of our current understanding of epigenetic regulation in the heart, and will stimulate further research in this exciting field.

321p ladongphongthanh1008 22-04-2024 0 0   Download

Ebook "Folding for the synapse" addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Molecular chaperones have been studied in relation to de novo protein folding, but there is increasing awareness that chaperone function is required for the regulation of protein dynamics when functioning physiologically as an isolated moiety or part of a protein complex.

315p tracanhphuonghoa1007 22-04-2024 0 0   Download

Ebook "Mitochondrial oxidative phosphorylation: Nuclear-encoded genes, enzyme regulation, and pathophysiology" focuses on new developments in mitochondrial morphology, biogenesis, and evolution, as well as in structure and regulatory functions of the enzyme complexes of OxPhos by experts in their fi elds. Particular emphasis is given to the oxygen consuming enzyme of the respiratory chain, cytochrome c oxidase, representing a controlling step of OxPhos.

378p tracanhphuonghoa1007 22-04-2024 0 0   Download

Ebook "Cell biology of the axon" focus on endogenous cytoskeletal systems that structurally organize the axon, confer tensile strength, and mediate intracellular transport and growth cone motility. Specifically, Shea et al. address issues of how organizational dynamics of neurofilaments are regulated, including mechanisms of transport, and how dysregulation of transport can contribute to motor neuron disease.

369p tracanhphuonghoa1007 22-04-2024 0 0   Download

The article determines the effectiveness of currency control body activities in the Russian Federation by supply chain management. Currency regulation and currency control, the methodology of international calculations for export-import transactions is one of financial policy trends in the Russian Federation. The instruments of currency regulation and currency control affect the balance of payments, the rate of national currency, the level of foreign exchange reserves, provide the necessary dynamics of foreign trade development.

8p longtimenosee09 08-04-2024 1 0   Download

The liver X receptors (LXRs, NR1H2 and NR1H3) and peroxisome proliferator-activated receptor gamma (PPARG, NR1C3) nuclear receptor transcription factors (TFs) are master regulators of energy homeostasis. Intriguingly, recent studies suggest that these metabolic regulators also impact tumor cell proliferation.

16p vioraclene 31-03-2024 4 2   Download

Medical digital twins are computational disease models for drug discovery and treatment. Unresolved problems include how to organize and prioritize between disease-associated changes in digital twins, on cellulomeand genome-wide scales. We present a dynamic framework that can be used to model such changes and thereby prioritize upstream regulators (URs) for biomarker- and drug discovery.

21p viellison 28-03-2024 3 2   Download

Ebook "Actin-monomer-bindingproteins (Molecular biology intelligence unit series)" summarizes the current knowledge on actin dynamics and presents examples of how actin monomer binding proteins regulate actin filament assembly and contribute to various cellular processes. It is important to note that many actin monomer binding proteins also display other activities besides interaction with unpolymerized actin.

127p duongthandue0501 28-02-2024 4 1   Download

In ebook "Nuclear dynamics: Molecular biology and visualization of the nucleus" the dynamics of nuclear structures described furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.

285p tachieuhoa 28-01-2024 6 2   Download

This paper proposes an automatic voltage regulator (AVR) based on series voltage compensation mechanism by AC chopper. The proposed AVR consists of a pulse-width-modulated (PWM) AC chopper and a transformer for series voltage compensation. The AC chopper circuit provides direct AC power without the need for an energy storage element, thus reducing the size and cost of the AVR.

4p vimarillynhewson 02-01-2024 6 3   Download

Ebook "Plant chromatin dynamics: Methods and protocols" provides a comprehensive collection of protocols that can be used to study plant chromatin structure and composition. Chapters divided into three sections detail the profiling of chromatin features in relation to epigenetic regulation, investigate the interaction between chromatin modifications and gene regulation, and explore the 3D spatial organization of the chromatin inside the nucleus.

650p lucchinguyen 28-12-2023 6 3   Download

Part 1 book "Dynamics in animal nutrition" includes content: Understanding nutritional immunomodulation - Th1 versus Th2; basis and regulation of gut barrier function and epithelial cell protection - Applications to the weaned pig, effects of oxidative stress and selenium supplementation on piglets and the underlying mechanisms; functional amino acids in swine nutrition and production, glucose metabolism in reproductive sows.

113p oursky07 23-10-2023 7 2   Download

Part 1 book "Hormones and reproduction of vertebrates (Vol 4 - Birds)" includes content: Neuroendocrine control of reproduction in birds; avian testicular structure, function, and regulation; organization and functional dynamics of the avian ovary; maternal hormones in avian eggs.

134p oursky05 20-09-2023 6 2   Download

Part 1 book "Handbook of industrial organization" includes content: Recent developments in the theory of regulation; the economic analysis of advertising; empirical models of entry and market structure; a framework for applied dynamic analysis in IO; coordination and lock in - competition with switching costs and network effects.

541p oursky03 21-08-2023 5 4   Download

The paper "The challenges faced by developing countries regarding transfer pricingregulation - A case study of Vietnam" offers a broad and complete interdisciplinary vision, not only from policy makers, tax authorities but enterprises and consultant firms such as Big 4 towards the change in current transfer pricing regulation. Besides giving comments on new law in Vietnam, we foresee the change in transfer pricing regime of developing countries in future.

8p nhanchienthien 25-07-2023 4 4   Download

Study of epigenetics is currently a high-impact research topic. Multi stage methylation is also an area of high-dimensional prospect. In this article, we provide a new study (intra and inter-species study) on brain tissue between human and rhesus on two methylation cytosine variants based data-profiles (viz., 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) samples) through TF-miRNA-gene network based module detection.

22p vinarcissa 21-03-2023 1 1   Download

(BQ) Ebook Brain, behavior and epigenetics: Part 2 presents the following content: Chapter 8: The Strategies of the Genes: Genomic Conflicts, Attachment Theory, and Development of the Social Brain; Chapter 9: Genomic Imprinting Effects on Brain and Behavior: Future Directions; Chapter 10: Epigenetic Influence of the Social Environment; Chapter 11: Toward an Understanding of the Dynamic Interdependence of Genes and Environment in the Regulation of Phenotype; Chapter 12: Histone Deacetylase Inhibitors: A Novel Therapeutic Approach for Cognitive Disorders; Chapter 13: Epigenetic Mechanisms of ...

175p runordie7 30-08-2022 7 2   Download

This study suggests an optimal coverage model aimed at the optimal deployment of Wireless sensor networks (WSN) based on improving the artificial bee colony (ABC) algorithm. The distance between the sensor nodes is regulated reasonably by implementing quasi-gravitation and quasi-coulomb power. Also, with a low regional repetition rate, the ABC algorithm can achieve fast optimization. Besides, to minimize node energy consumption, the sensing radius of WSN nodes is dynamically modified.

10p linyanjun_2408 21-04-2022 22 3   Download

Histone lysine acylations by short-chain fatty acids are distinct from the widely studied histone lysine acetylation in chromatin, although both modifications are regulated by primary metabolism in mammalian cells. It remains unknown whether and how histone acylation and acetylation interact to regulate gene expression in plants that have distinct regulatory pathways of primary metabolism.

14p vigalileogalilei 27-02-2022 7 1   Download

Recently, DNA methylation was proposed to regulate fleshy fruit ripening. Fleshy fruits can be distinguished by their ripening process as climacteric fruits, such as tomatoes, or non-climacteric fruits, such as strawberries. Tomatoes undergo a global decrease in DNA methylation during ripening, due to increased expression of a DNA demethylase gene. The dynamics and biological relevance of DNA methylation during the ripening of non-climacteric fruits are unknown.

14p vigalileogalilei 27-02-2022 8 1   Download