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Early migration
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Ovarian cancer is one of the most common gynecological malignancies due to the lack of early symptoms, early diagnosis and limited screening. Therefore, it is necessary to understand the molecular mechanism underlying the occurrence and progression of ovarian cancer and to identify a basic biomarker for the early diagnosis and clinical treatment of ovarian cancer.
13p
vikoch
27-06-2024
1
1
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Receptor-type tyrosine-protein phosphatase T (PTPRT) is a transmembrane protein that is involved in cell adhesion. We previously found that PTPRT was downregulated in multiple cancer types and the mutation of PTPRT was associated with cancer early metastasis. However, the impacts of PTPRT downregulation on tumour proliferation, invasion, and clinical interventions such as immune checkpoint inhibitor (ICI) therapies remained largely unknown.
13p
vikoch
27-06-2024
2
1
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Early childhood overweight and obesity is a growing public health concern worldwide. Few recent studies have addressed how time trends varied by sociodemographic characteristics at the regional level using large and high-quality data. This study determines how time trends vary in the prevalence of early childhood overweight and obesity by age, gender, and migration background at the regional level.
8p
viferrari
28-11-2022
6
3
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The Hellenic subduction system governs the entire Aegean region through the creation of a migrating magmatic arc that has existed since the beginning of the Early Cenozoic. The Karadağ Pluton is situated in the NW part of Turkey and represents one of the distinct snapshots of this subduction system during the Late Oligocene-Early Miocene Period.iod. It consists of 2 major lithological units, based on their petrographic and geochemical features, comprising: 1) main plutonic facies (SiO2 < 70 wt.
34p
tanmocphong
29-01-2022
12
1
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The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial to mesenchymal transition in order to migrate and differentiate throughout the developing embryo. The derivative cell types give rise to multiple tissues, including the craniofacial skeleton, peripheral nervous system and skin pigment cells.
13p
vibeauty
23-10-2021
10
0
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The purpose of this study was to determine the feasibility of Roentgen Stereophotogrammetric Analysis (RSA) in total joint arthroplasty of the trapeziometacarpal (TMC) joint of the thumb.
5p
vioregon2711
22-02-2021
5
1
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For osteoporotic femoral neck fractures, suitable bone-implant stability is critical for pain relief, early return to daily activities and reduction of complications. Teriparatide (parathyroid hormone [PTH1-34]) can improve bone-implant stability in some basic studies.
9p
vioregon2711
22-02-2021
12
2
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Early femoral stem subsidence following a cementless THA is correlated with aseptic loosening of the femoral component. The short femoral stems allow bone sparing and implantation through a minimally invasive approach; however, due to their metaphyseal anchoring, they might demonstrate different subsidence pattern than the conventional stems.
9p
vivermont2711
28-01-2021
7
1
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The vertebrate heart consists of three cell layers: The innermost endothelium, the contractile myocardium and the outermost epicardium. The epicardium is vital for heart development and function, and forms from epicardial progenitor cells (EPCs), which migrate to the myocardium during early development
9p
viwyoming2711
16-12-2020
12
1
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As one of the malignant tumors most often affecting children and young adults, Ewing sarcoma (ES) is characterized by early metastasis contributing to unfavorable prognosis. However, the molecular mechanisms responsible for ES metastasis remain poorly understood. In this study, we aimed to explore whether Wnt5a, a putative pro-metastatic factor, plays a role in ES metastasis.
10p
viirene2711
03-10-2020
11
1
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Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack of reliable biomarkers for early diagnosis and limited targeted therapies. Early diagnostic markers and novel therapeutic targets can significantly improve clinical management of gallbladder cancer.
12p
vimoscow2711
29-08-2020
6
0
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The incidence of Cholangiocellular Carcinoma (CCA) is increasing in the western world. The tumour has a high proportion of desmoplastic stroma and is correlated with a worse prognosis when cancer associated myofibroblasts (CAFs) are present. Recent studies showed promising results after liver transplantation (LTx) in non-resectable early stage CCA.
12p
vinaypyidaw2711
26-08-2020
14
2
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Colorectal cancer (CRC) is closely linked to Wnt signalling, with 94 % of cases exhibiting a Wnt related mutation. ROR2 is a receptor tyrosine kinase that is thought to repress β-catenin dependent Wnt signalling.
12p
vimale2711
25-08-2020
11
2
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Malignant melanoma (MM) is one of the high degree of malignancy and early prone to blood and lymph node metastasis. There is not cured for MM. Tan II A has been reported to reduce cancer cell proliferation. But the mechanism by which Tan II A inhibited melanoma growth are not well characterized.
11p
vidhaka2711
31-07-2020
7
1
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Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed early; however advanced Rb can metastasize through routes that involve invasion of the choroid, sclera and optic nerve or more broadly via the ocular vasculature.
11p
vidhaka2711
31-07-2020
25
3
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The identification of mental health problems early in life can increase the well-being of children and youth. Several studies have reported that youth who experience mental health disorders are also at a greater risk of developing psychopathological conditions later in life, suggesting that the ability of researchers and clinicians to identify mental health problems early in life may help prevent adult psychopathology.
11p
viamsterdam2711
07-01-2020
21
1
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The clinical manifestations of schistosomiasis pass by acute, sub acute and chronic stages that mirror the immune response to infection. The later includes in succession innate, TH1 and TH2 adaptive stages, with an ultimate establishment of concomitant immunity. Some patients may also develop late complications, or suffer the sequelae of co-infection with other parasites, bacteria or viruses. Acute manifestations are species-independent; occur during the early stages of invasion and migration, where infection-naivety and the host’s racial and genetic setting play a major role.
12p
kethamoi1
17-11-2019
11
1
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In Africa, as in other parts of the world, civilization emerged in areas where farming was mastered. Some African civilizations later became wealthy by trading ivory, gold, iron, salt, and other goods. Migration and the spread of Islam were also important in the development of African societies.
109p
tangtuy05
01-04-2016
49
8
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Dynamic routing protocols have evolved over several years As networks have evolved and become more complex, new routing protocols have emerged. Most institutions have migrated to new protocols, others are still in use. The first version of RIP was released in 1982, but some of the basic algorithms within the protocol were used on the ARPANET as early as 1969.
52p
vanmanh1008
21-05-2013
68
5
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This novel modeling technique provides a powerful new tool for tissue evaluation in osteoarthritis research, cartilage tissue engineering and related animal studies. Once the approach is fully validated against the gold standard (Pg chemical assays), lu plans to migrate the current table-top indentation setup to a handheld micro-indentation platform.
164p
loixinloi
08-05-2013
42
3
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