![](images/graphics/blank.gif)
Empirical Bayes models
-
Single-cell transcriptomics reveals gene expression heterogeneity but suffers from stochastic dropout and characteristic bimodal expression distributions in which expression is either strongly non-zero or non-detectable. We propose a two-part, generalized linear model for such bimodal data that parameterizes both of these features.
13p
viaristotle
29-01-2022
13
0
Download
-
To determine which changes in the host cell genome are crucial for cervical carcinogenesis, a longitudinal in vitro model system of HPV-transformed keratinocytes was profiled in a genome-wide manner. Four cell lines affected with either HPV16 or HPV18 were assayed at 8 sequential time points for gene expression (mRNA) and gene copy number (DNA) using high-resolution microarrays.
16p
vikentucky2711
26-11-2020
11
2
Download
-
Conventional differential gene expression analysis by methods such as student’s t-test, SAM, and Empirical Bayes often searches for statistically significant genes without considering the interactions among them.
14p
vioklahoma2711
19-11-2020
17
1
Download
-
Combining genomic data sets from multiple studies is advantageous to increase statistical power in studies where logistical considerations restrict sample size or require the sequential generation of data. However, significant technical heterogeneity is commonly observed across multiple batches of data that are generated from different processing or reagent batches, experimenters, protocols, or profiling platforms.
15p
viconnecticut2711
28-10-2020
13
1
Download
-
We introduce a new method for disambiguating word senses that exploits a nonlinear Kernel Principal Component Analysis (KPCA) technique to achieve accuracy superior to the best published individual models. We present empirical results demonstrating significantly better accuracy compared to the state-of-the-art achieved by either na¨ve Bayes ı or maximum entropy models, on Senseval-2 data. We also contrast against another type of kernel method, the support vector machine (SVM) model, and show that our KPCA-based model outperforms the SVM-based model. ...
8p
bunbo_1
17-04-2013
51
1
Download
-
Recent approaches to text classication have used two dierent rst-order probabilistic models for classication, both of which make the naive Bayes assumption. Some use a multi-variate Bernoulli model, that is, a Bayesian Network with no dependencies between words and binary word features (e.g. Larkey and Croft 1996; Koller and Sahami 1997). Others use a multinomial model, that is, a uni-gram language model with integer word counts (e.g. Lewis and Gale 1994; Mitchell 1997).
8p
giamdocamnhac
06-04-2013
49
5
Download
-
The lake ecosystem of Hanoi has a very important role. However, the water quality in the lakes of Hanoi is declining; they're more and more polluted. Among that, eutrophication is the most popular one. Therefore, the assessment and prediction of eutrophication is necessary. One of the effective tools for assessing and predicting eutrophycation is the use of mathematical models. In this paper, we used the Vollenweider model, empirical watershed model and Jorgensen model to determine the eutrophycation of Bay Mau Lake by phosphorous concentration in the lake water.
6p
dem_thanh
22-12-2012
51
4
Download
-
The Aqua Augusta, an aqueduct built by Octavian (63 BC–AD 14; later known as Augustus, the first emperor of the Roman Empire), was completed in the late first century BC and provided an uninterrupted supply of pressurized water to eight towns around the bay, including Pompeii. The arrival of a constant source of running water in these cities allowed residents to design and grow more elaborate gardens. Gardeners were able to accentuate their landscape designs with springs, water courses, pools, and fountains modeled after Greek statuary.
12p
connhobinh
07-12-2012
51
3
Download
-
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Research Article An Empirical Model for Probability of Packet Reception in Vehicular Ad Hoc Networks
12p
sting08
20-02-2012
44
4
Download
-
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Cost-effectiveness of micafungin as an alternative to fluconazole empiric treatment of suspected ICU-acquired candidemia among patients with sepsis: a model simulation...
11p
thulanh18
28-10-2011
66
2
Download
-
Tuyển tập các báo cáo nghiên cứu về lâm nghiệp được đăng trên tạp chí lâm nghiệp Original article đề tài: Evaluation of a semi-empirical model for predicting fine root biomass in compositionally complex woodland vegetation...
8p
toshiba5
15-09-2011
45
1
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)