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Endogenous molecules
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Plant elicitor peptides (Peps) are endogenous molecules that induce and amplify the first line of inducible plant defense, known as pattern-triggered immunity, contributing to protect plants against attack by bacteria, fungi and herbivores. Pep topic application and transgenic expression have been found to enhance disease resistance in a small number of model plant-pathogen systems.
12p
vinarcissa
21-03-2023
2
1
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Isatin, 1H -indoline-2,3-dione, an endogenous compound, is also a synthetically versatile molecule that possesses a diversity of biological activities including anticonvulsant, antibacterial, antifungal, antiviral, anticancer, and cytotoxic properties. Based on the promising cytotoxic activity studies on N -substituted isatin derivatives, a series of 18 derivatives of 2-(2,3-dioxo-2,3-dihydro-1H -indol-1-yl)-N -phenylacetamide were designed, synthesized, and characterized according to their analytical and spectral data.
9p
langthannam
29-12-2021
12
1
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Spinach is a beneficial annual vegetable species and sensitive to the bolting or early flowering, which causes a large reduction in quality and productivity. Indeed, bolting is an event induced by the coordinated effects of various environmental factors and endogenous genetic components. Although some key flowering responsive genes have been identified in spinach, non-coding RNA molecules like long non-coding RNAs (lncRNAs) were not investigated yet.
23p
vilarryellison
29-10-2021
5
0
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To reduce costs of rearing replacement heifers, researchers have focused on decreasing age at breeding and first calving. To increase returns upon initiation of lactation the focus has been on increasing mammary development prior to onset of first lactation.
23p
viseulgi2711
31-08-2021
37
0
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MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, thus orchestrating many physiological processes.
13p
vigiselle2711
30-08-2021
12
1
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Glutathione S-transferases (GSTs) represent a ubiquitous gene family encoding detoxification enzymes able to recognize reactive electrophilic xenobiotic molecules as well as compounds of endogenous origin.
15p
vijichea2711
28-05-2021
10
1
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The characteristics of circRNA as competing endogenous RNA in pathogenesis of acute myeloid leukemia
As one of the novel molecules, circRNA has been identified closely involved in the pathogenesis of many diseases. However, the function of circRNA in acute myeloid leukemia (AML) still remains unknown.
10p
vianrose2711
27-04-2021
17
1
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High expression levels of Inhibitors of Apoptosis Proteins (IAPs) have been correlated with poor cancer prognosis and block the cell death pathway by interfering with caspase activation. SMAC-mimetics are small-molecule inhibitors of IAPs that mimic the endogenous SMAC and promote the induction of cell death by neutralizing IAPs.
16p
vimale2711
25-08-2020
12
2
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MicroRNAs (miRNAs) are highly conserved class of short endogenous non-coding small RNA molecules of about 18–22 nucleotide in length. MicroRNAs negatively regulate the gene expression by degrading target mRNA. In the present study, comparative genomic based approach was used to identify and characterize new conserved microRNAs in “orphan legume crop” pigeon pea (Cajanus cajan L.) using expressed sequence tags (ESTs) by in silico method. A total of 4,621 unique previously reported microRNAs were used for homology search in 25,576 ESTs of pigeon pea for identifying conserved miRNAs.
11p
nguaconbaynhay6
24-06-2020
12
2
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Bcl-2 family members play an important role in the development of malignant lymphoma and can induce drug resistance in anticancer treatment. The development of small molecules targeting Bcl-2 family proteins may be a new strategy for the treatment of malignant lymphoma.
12p
vikuala271
13-06-2020
4
0
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Plant immune responses can be induced by endogenous and exogenous signaling molecules. Recently, amino acids and their metabolites have been reported to affect the plant immune system.
10p
vihashirama2711
21-05-2020
12
1
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The signaling properties of the gasotransmitter molecule hydrogen sulfide (H2S), which is endogenously generated in plant cells, are mainly observed during persulfidation, a protein post-translational modification (PTM) that affects redox-sensitive cysteine residues. There is growing experimental evidence that H2S in higher plants may function as a mechanism of response to environmental stress conditions.
7p
partimesinhvien
08-05-2020
31
0
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Moso bamboo (Phyllostachys edulis) is a well-known bamboo species of high economic value in the textile industry due to its rapid growth. Phytohormones, which are master regulators of growth and development, serve as important endogenous signals.
15p
vichoji2711
29-04-2020
11
1
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Phytocystatins (PhyCys) act as endogenous regulators of cysteine proteases (CysProt) involved in various physiological processes. Besides, PhyCys are involved in plant reactions to abiotic stresses like drought or darkness and have been used as effective molecules against different pests and pathogens.
13p
vishikamaru2711
29-04-2020
10
1
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Uric acid is synthesized mainly in the liver, intestines and the vascular endothelium as the end product of an exogenous pool of purines, and endogenously from damaged, dying and dead cells, whereby nucleic acids, adenine and guanine, are degraded into uric acid. Mentioning uric acid generates dread because it is the established etiological agent of the severe, acute and chronic inflammatory arthritis, gout and is implicated in the initiation and progress of the metabolic syndrome.
7p
trinhthamhodang1
14-11-2019
28
1
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Our body is endowed with several endogenous anti-microbial compounds such as interferon, cytokines, free radicals, etc. However, little attention has been paid to the possibility that lipids could function as antimicrobial compounds. In this short review, the antimicrobial actions of various polyunsaturated fatty acids (PUFAs, mainly free acids) and their putative mechanisms of action are described.
10p
trinhthamhodang1
14-11-2019
12
1
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This study investigated the correlation between endogenous levels of some signal compounds [nitric oxide (NO), salicylic acid (SA), abscisic acid (ABA)] and the antioxidant system in response to chilling stress in maize (Zea mays L.). The results showed that chilling stress caused oxidative damage, and changes in signal molecules (NO, SA, and ABA) and NR activity in maize.
8p
vikimsa
22-02-2019
20
0
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MicroRNAs (miRNAs) are important noncoding regulatory RNAs. They are expressed endogenously and are 18–26 nucleotides in length. These small molecules are conserved evolutionarily within the same kingdom and their conserved nature becomes an important logical tool for the quest of conserved miRNAs in other species by homology search using bioinformatics tools.
19p
caplock2711
21-02-2019
24
1
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In the horseshoe crab, bacterial lipopolysaccharide (LPS) induces exocyto-sis by granular hemocytes, resulting in the secretion of various defense molecules, such as lectins and antimicrobial peptides, via a G protein-mediating signaling pathway. This response is a key component of the horseshoe crab innate immune response against infectious microorganisms. Here, we report an endogenous amplification mechanism for LPS-induced hemocytes exocytosis.
9p
fptmusic
11-04-2013
42
1
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Cdx1 and Cdx2, which are transcription factors regulating normal intesti-nal development, have been studied as potential key molecules in the pathogenesis of the precancerous intestinal metaplasia of the human stomach. However, the regulation of Cdx1 expression in the intestinal metaplasia is poorly understood.
11p
viettel02
20-02-2013
46
1
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