Environmental lung disease

Associations of low lung function with features of poor cardio-metabolic health have been reported. It is, however, unclear whether these co-morbidities reflect causal associations, shared genetic heritability or are confounded by environmental factors.

13p vibransone 28-03-2024 5 2   Download

Part 1 book "Biomarkers in medicine, drug discovery, and environmental health" includes content: Biomarkers - An evolutionary perspective; genomics; proteomics for biomarker discovery; metabolic profiling for biomarker discovery; the bittersweet promise of glycobiology, biomarkers of alzheimer's and parkinson's disease; biomarkers of cardiac injury; lung injury biomarkers; translational biomarkers of acute drug induced liver injury - the current state, gaps, and future opportunities; biomarkers of acute kidney injury; in search of biomarkers for drug induced vascular injury.

336p oursky09 12-11-2023 5 3   Download

Part 1 book "Biomarkers - In medicine, drug discovery, and environmental health" includes content: Biomarkers - An evolutionary perspective; genomics; proteomics for biomarker discovery; metabolic profiling for biomarker discovery, the bittersweet promise of glycobiology; biomarkers of Alzheimer's and Parkinson's disease; biomarkers of cardiac injury; lung injury biomarkers; translational biomarkers of acute drug induced liver injury - the current state, gaps, and future opportunities; biomarkers of acute kidney injury; in search of biomarkers for drug induced vascular injury.

336p oursky07 23-10-2023 3 1   Download

Emissions from diesel vehicles and biomass burning are the principal sources of primary ultrafine particles (UFP). The exposure to UFP has been associated to cardiovascular and pulmonary diseases, including lung cancer. Although many aspects of the toxicology of ambient particulate matter (PM) have been unraveled, the molecular mechanisms activated in human cells by the exposure to UFP are still poorly understood.

15p vibeauty 23-10-2021 5 0   Download

Reduced lung function in patients with chronic obstructive pulmonary disease (COPD) is likely due to both environmental and genetic factors. We report here a targeted high-throughput DNA sequencing approach to identify new and previously known genetic variants in a set of candidate genes for COPD.

10p vimaine2711 26-03-2021 14 1   Download

The CAnadian REgistry for Pulmonary Fibrosis (CARE-PF) is a multi-center, prospective registry designed to study the natural history of fibrotic interstitial lung disease (ILD) in adults. The aim of this crosssectional sub-study was to describe the baseline characteristics, risk factors, and comorbidities of patients enrolled in CARE-PF to date.

9p vimaine2711 26-03-2021 7 2   Download

Epidemiological research on health effects of livestock exposure in population subgroups with compromised respiratory health is still limited. The present study explored the association between livestock exposure and comorbid/concurrent conditions in patients with overlapping diagnoses of asthma and COPD.

10p vimaine2711 26-03-2021 12 2   Download

Chronic hypersensitivity pneumonitis (cHP) is a disease caused by exposure to inhaled environmental antigens. Diagnosis of cHP is influenced by the awareness of the disease prevalence, which varies significantly in different regions, and how clinicians utilize relevant clinical information.

7p vimaine2711 26-03-2021 9 2   Download

Exposure to environmental tobacco smoke (ETS) leads to higher rates of pulmonary diseases and infections in children. To study the biochemical changes that may precede lung diseases, metabolomic effects on fetal and maternal lungs and plasma from rats exposed to ETS were compared to filtered air control animals.

15p viwyoming2711 16-12-2020 11 1   Download

Exposure to arsenic via drinking water is a significant environmental issue affecting millions of people around the world. Exposure to arsenic during foetal development has been shown to impair somatic growth and increase the risk of developing chronic respiratory diseases.

9p vienzym2711 03-04-2020 14 1   Download

By WHO forecasts, a further increase in the prevalence and mortality of COPD among people of working age is predicted, due to uncontrolled environmental pollution, a tobacco pandemic, an increase in the level of allergens and a genetic predisposition. In chronization and progression of COPD, there is a violation of cellular and humoral immunity, production of pro-inflammatory cytokines of phagocytic cell activity that contribute to the persistence of the inflammatory process in the lungs.

5p cothumenhmong3 22-02-2020 28 0   Download

(bq) part 1 book “kendig's disorders of the respiratory tract in children” has contents: the history and physical examination, molecular determinants of lung morphogenesis, basic genetics and epigenetics of childhood lung disease, environmental contributions to respiratory disease in children, the surfactant system,… and other contents.

2361p tieu_vu15 07-09-2018 58 4   Download

(bq) part 1 book “high-resolution ct of the lung” has contents: normal lung anatomy, technical aspects of high-resolution ct, diffuse pulmonary neoplasms and pulmonary lymphoproliferative diseases, pneumoconiosis, occupational, and environmental lung disease, miscellaneous infiltrative lung diseases, cystic lung diseases,… and other contents.

326p tieu_vu15 07-09-2018 16 1   Download

(bq) part 2 book “high-resolution ct of the lung” has contents: pneumoconiosis, occupational, and environmental lung disease, hypersensitivity pneumonitis and eosinophilic lung diseases, miscellaneous infiltrative lung diseases, cystic lung diseases, airways diseases,… and other contents.

421p tieu_vu15 07-09-2018 20 1   Download

part 2 book “revision notes for the respiratory medicine specialty certificate examination” has contents: eosinophilic lung disease, sleep disorders, disorders of the mediastinum and pleura, occupational and environmental lung disease, lung transplantation, invasive and non-invasive ventilation,… and other contents.

61p tieu_vu13 06-08-2018 27 2   Download

Exposure to tobacco smoke both prenatally and after birth is associated with measurable harmful effects including a greater risk of developing asthma-like symptoms in early childhood. However, evidence of increased risk of allergic diseases is uncertain77, 78. Distinguishing the independent contributions of prenatal and postnatal maternal smoking is problematic79. However, studies of lung function immediately after birth have shown that maternal smoking during pregnancy has an influence on lung development37.

98p dacotaikhoan 26-04-2013 29 2   Download

Population groups that are potentially more vulnerable than others to indoor air pollution are children, pregnant women, elderly people, and people suffering from cardiovascular or respiratory diseases. Depending on their age, children may be more vulnerable than adults to certain toxic substances, like lead and tobacco smoke. Even at low levels, air pollutants may disrupt the development of their lungs, cause cough, bronchitis and other respiratory diseases, and make asthma worse.

6p doipassword 01-02-2013 45 5   Download

In the year 2004, outdoor air pollution in urban areas was responsible for almost 1.2 million deaths (2% of all deaths) and 0.6% of the global burden of disease. 1 Transportation-related air pollution, which is a significant contributor to total urban air pollution, increases the risks of cardiopulmonary-related deaths and non-allergic respiratory disease. Some evidence supports an association of transportation-related air pollution with increased risks of lung cancer, myocardial infarction, increased inflammatory response and adverse pregnancy outcomes (e.g.

5p doipassword 01-02-2013 60 5   Download

Air pollution is one of the most serious environmental threats to urban populations (Cohen 2005). Exposures vary among and within urban areas, but all people living in cities are exposed, and many are harmed, by current levels of pollutants in many large cities. Infants, young children, seniors and people who have lung and heart conditions are especially affected, but even young, healthy adults are not immune to harm from poor air quality.

42p saimatkhauroi 01-02-2013 49 4   Download

About a third of the world’s population is infected with Mycobacterium tuberculosis. Tuberculosis remains one of the biggest killers among infectious diseases, with up to three million people dying from tuberculosis each year (Dye 1999). Diagnosis of tuberculosis generally relies on smear microscopy and culture of the sputum. The disease typically results in progressively destructive lung lesions but may affect almost any part of the body, usually with advanced wasting and death inmore than half of cases in the absence of intervention.

4p taisaocothedung 12-01-2013 38 2   Download