Enzyme activity

Hippeastrum reticulatum (L.Hér.) Herb is a species of the Hippeastrum Herb. genus. Screening studies have shown that this species has the ability to inhibit the enzyme acetylcholinesterase. So far, research on this species is still very limited.

5p viuchiha 03-01-2025 1 0   Download

A reaction happens need the energy to vibrate the molecules and the reactant concentration enough. The energy here is often provided by heat. However, in living system, high temperature may harm the biological structure Truly that the concentration in living system is very low. So living organisms solve these problems by using enzyme

94p zingzing09 21-10-2012 65 9   Download

Two enzymes control the rearrangement of carbon skeletons which result in the production of Glyceraldehyde-3-phosphate and Fructose-6-phosphate. Transketolase transfers C2 units: TPP requiring enzyme like pyruvate dehydrogenase Transaldolase transfers C3 units: uses a shiffs base with an active lysine group

44p zingzing09 21-10-2012 53 11   Download

Master's thesis of Science "Investigation into the modulation of circadian clock proteins by dietary compounds and small molecules" is structured as follows: Chapter 1 Introduction; Chapter 2 Identification of novel bioactive compounds from Olea europaea by evaluation of chemical compounds in the OliveNetTM library: in silico bioactivity and molecular modelling, and in vitro validation of hERG activity; Chapter 3 Modulation of circadian core clock proteins by dietary compounds; Chapter 4 Molecular mechanisms of action of selected olive phenolics against epigenetic modifiers and the structur...

235p runthenight04 02-02-2023 5 3   Download

Study on main chemical constituents of two Gymnema species including Gymnema sylvestre and Gymnema latifolium growing in Vietnam and evaluate the inhibitory effect of α-glucosidase and α-amylase enzymes of isolated compounds.

27p closefriend09 16-11-2021 19 4   Download

Objectives of the dissertation: Research and synthesize and determine the hybrid compound structure containing Quinazoline frame. Research on carcinogenic activity and inhibition of acetylcholinesterase enzyme of synthetic compounds..

26p extraenglish 24-05-2021 22 3   Download

Synthesis and structural determination of some 4-aminoquinazoline derivatives containing prop-2-yn-1-yloxy substituents at C-6 position; research and synthesize and determine the hybrid compound structure containing Quinazoline frame; research on carcinogenic activity and inhibition of acetylcholinesterase enzyme of synthetic compounds; studying protein docking and predicting the pharmacokinetic properties of some compounds that inhibit the enzyme acetylcholinesterase.

26p capheviahe27 23-02-2021 42 4   Download

The objectives of the thesis: Study on chemical constituents of three Trichosanthes species (T. baviensis, T. anguina, and T. kirilowii) grown in Vietnam; evaluation of cytotoxic and tyrosinase enzyme inhibitory activities of isolated compounds from the above mentioned Trichosanthes species.

14p capheviahe26 25-01-2021 19 3   Download

Study on chemical constituents of two Knema species including Knema pachycarpa and Knema saxatilis growing in Vietnam; evaluate cytotoxic and cetylcholinesterase enzyme inhibitory activitiesof isolates to find out bioactive compounds.

25p capheviahe26 25-01-2021 19 4   Download

Field experiment was conducted on a sandy loam soil during winter irrigated season of 2015-16 at Department of Farm Management, Tamil Nadu Agricultural University, Coimbatore to study the effect of various organic manures and weed control methods on yield attributes and soil enzyme activities of organic cotton cultivation. The experiment was laid out in strip plot design and replicated thrice. Treatments viz.

9p chauchaungayxua6 26-06-2020 19 3   Download

Nuclear factor erythroid-2 related factor 2 (Nrf2) is a crucial transcription factor that regulates the expression of defensive antioxidants and detoxification enzymes in cells. In a previous study, we showed that expression of the Nrf2 gene is regulated by an epigenetic modification. Rauvolfia verticillata, a traditional Chinese herbal medicine widely used in China, possesses anticancer and antioxidant effects. In this study, we investigated how Nrf2 is epigenetically regulated by reserpine, the main active component in R. verticillata, in mouse skin epidermal JB6 P+ cells.

11p caothientrangnguyen 09-05-2020 17 2   Download

The research objective of the dissertation is to research and apply enzyme technology to hydrolysis of plant glycoid compounds, creating higher activity products and developing green research in organic chemistry.

27p xacxuoc4321 09-07-2019 46 3   Download

The research objective of the thesis is to select microorganisms capable of producing laccase, laccaselike from Ba Vi National Forest area, in herbicide / dioxin contaminated soil at Bien Hoa airport. Assessing the ability of decomposing herbicides containing dioxin and reactive dyes by laccase, laccase-like and VSV strains were selected to guide the application in defense activities.

27p xacxuoc4321 11-07-2019 45 5   Download

Shikimate kinase was chosen as a convenient representative example of the subclass of a/b proteins with which to examine the mechanism of protein folding. In this paper we report on the refolding of the enzyme after denaturation in urea. As shown by the changes in secondary and tertiary structure monitored by far UV circular dichroism (CD) and fluorescence, respectively, the enzyme was fully unfolded in 4 M urea. From an analysis of the unfolding curve in terms of the two-state model, the stability of the folded state could be estimated as 17 kJÆmol)1.

9p system191 01-06-2013 48 5   Download

Trehalose metabolism is an essential component of the stress response in yeast cells. In this work we show that the products of the principal genes involved in trehalose metabolism in Schizosaccharomyces pombe, tps1+ (coding for trehalose6-P synthase, Tps1p), ntp1+ (encoding neutral trehalase, Ntp1p) and tpp1+ (that codes for trehalose-6-P phosphatase, Tpp1p), interact in vitro with each other and with themselves to form protein complexes. Disruption of the gene tps1+ blocks the activation of the neutral trehalase induced by heat shock but not by osmotic stress.

9p system191 01-06-2013 28 4   Download

Certain amino acids, like glutamine and leucine, induce an anabolic response in liver. They activate p70 ribosomal protein S6 kinase (p70S6K) and acetyl-CoA carboxylase (ACC) involved in protein and fatty acids synthesis, respectively. In contrast, the AMP-activated protein kinase (AMPK), which senses the energy state of the cell and becomes activated under metabolic stress, inactivates by phosphorylation key enzymes in biosynthetic pathways thereby conserving ATP.

9p system191 01-06-2013 50 5   Download

Starch defines a semicrystalline polymer made of two different polysaccharide fractions. The A- and B-type crystalline lattices define the distinct structures reported in cereal and tuber starches, respectively. Amylopectin, the major fraction of starch, is thought to be chiefly responsible for this semicrystalline organization while amylose is generally considered as an amorphous polymer with little or no impact on the overall crystalline organization.

11p system191 01-06-2013 46 4   Download

Liver metabolism is influenced by hormones and nutrients. Amino acids such as glutamine or leucine induce an anabolic response, which resembles that of insulin in muscle and adipose tissue. In this work, the signalling pathways and the effects of insulin were compared to those of glutamine and leucine in isolated hepatocytes from normal and streptozotocin-diabetic rats.

9p system191 01-06-2013 47 5   Download

The design of b-glycosidases with planed substrate specificity for biotechnological application has received little attention. This is mostly a consequence of the lack of data on the molecular basis of the b-glycosidase specificity, namely data on the energy of the noncovalent interactions in the enzymetransition state complex. In an attempt to fill this gap, sitedirected mutagenesis and enzyme steady-state kinetic experiments with different substrates were conducted, using as model a digestive b-glycosidase (glycoside hydrolase family 1) from Spodoptera frugiperda (Lepidoptera) (Sfbgly50).

10p system191 01-06-2013 44 4   Download

Recent years have witnessed high levels of activity in identifying enzyme systems that catalyse H-transfer by quantum tunneling. Rather than being restricted to a small number of specific enzymes as perceived initially, it has now become an accepted mechanism for H-transfer in a growing number of enzymes. Furthermore, H-tunneling is driven by the thermally induced dynamics of the enzyme. In some of those enzymes that break stable C–H bonds the reaction proceeds purely by quantum tunneling, without the need to partially ascend the barrier.

7p system191 01-06-2013 40 3   Download