Enzyme regulation

We aimed to screen novel gene signatures for ovarian cancer (OC) and explore the role of biomarkers in OC via regulating pyroptosis using bioinformatics analysis. The proliferation, migration, and invasion were determined using cell counting kit and transwell assay. Enzyme-linked immunosorbent assay was applied to measure infammatory factors. The mRNA and protein expression were detected using real-time quantitative PCR and western blot.

15p vishanshan 27-06-2024 1 1   Download

Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the role of USP14 in the regulation of HCC development and progression remains unclear.

15p vikoch 27-06-2024 1 1   Download

This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.

15p vikoch 27-06-2024 1 1   Download

Ebook "Rb and tumorigenesis" examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.

129p ladongphongthanh1008 22-04-2024 3 3   Download

Ebook "CtBP family proteins" are unique in several aspects. They were the first among proteins containing a metabolic enzyme fold to be implicated in transcriptional regulation. The vertebrate CtBPs exhibit distinct nuclear and cytosolic activities. The crystal struaures of CtBPl and molecular modeling studies have illuminated the molecular basis of its dual activity and the interaction with target peptides.

131p ladongphongthanh1008 22-04-2024 5 2   Download

Ebook "Mitochondrial oxidative phosphorylation: Nuclear-encoded genes, enzyme regulation, and pathophysiology" focuses on new developments in mitochondrial morphology, biogenesis, and evolution, as well as in structure and regulatory functions of the enzyme complexes of OxPhos by experts in their fi elds. Particular emphasis is given to the oxygen consuming enzyme of the respiratory chain, cytochrome c oxidase, representing a controlling step of OxPhos.

378p tracanhphuonghoa1007 22-04-2024 3 2   Download

There are many evidences showing the fact that some hard conditions from environment, namely abiotic stress, could make several significantly negative impacts on crop production. However, some plant species can overcome these bad situations by complicated mechanisms. This study has shown the result of the construction the recombinant vector carrying CodA gene which could encode an enzyme, named choline oxidase, and is controlled by Rd29A promoter.

8p vilarry 01-04-2024 5 1   Download

Lymphoma represents a heterogeneous group of cancers affecting the lymphatic system, encompassing nonHodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). The majority of NHL cases originate from B cells. HL is characterized by the presence of rare Hodgkin and Reed-Sternberg cells. Within the context of the inflammatory response, two SH2 domain-containing protein tyrosine phosphatases (SHPs), namely SHP-1 and SHP-2, serve as negative regulators.

6p viellison 28-03-2024 2 2   Download

Ebook "Medical foods from natural sources" fills the gap in the literature by discussing the history of enteral nutrition; interpreting the statistics regarding worldwide need for enteral nutrition support and cost involved; enumerating the processing technology to develop natural ingredients-based enteral foods; and describing the results of prospective clinical trials and case studies conducted to evaluate the effectiveness of enteral foods based on natural ingredients.

224p manmanthanhla0201 26-02-2024 6 1   Download

Ebook "Bioreactor engineering research and industrial applications I: Cell factories" review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years.

247p lamquandat 28-12-2023 5 2   Download

Ebook "RNA metabolism and Gene expression in Archaea" focuses on the regulation of transcription and translation in Archaea; summarizes recent advances in our understanding of RNA metabolism in Archaea at all levels; provides a panoramic view of enzymes, machines and pathways used to synthesize, modify and break down RNA in Archaea; highlights the advantage of using Archaea as model organisms to study fundamental molecular mechanisms across the three domains of life;...

276p lucchinguyen 28-12-2023 5 2   Download

This study is to investigate the expression changes of lymphocyte migration regulation related proteins in urine exosomes of lung cancer patients, and further verify their correlation with the development and progression of lung cancer.

10p vialfrednobel 23-12-2023 4 3   Download

Part 2 book "Salmonella - Methods and protocols" includes content: Detecting non typhoid salmonella in humans by enzyme linked immunosorbent assays (ELISAs) - practical and epidemiological aspects; study of the STN protein in salmonella a regulator of membrane composition and integrity, development of a bacterial nanoparticle vaccine,...and other contents.

186p muasambanhan01 13-12-2023 8 4   Download

Part 1 book "Essentials of animal physiology" includes content: Cell structure and function; foodstuffs; biological oxidations; enzymes the biological catalysts; animal calorimetry; metabolism; digestion and absorption; water relations and ionic regulations; membrane physiology; temperature regulation; body fluids; circulation of blood.

281p oursky07 23-10-2023 4 2   Download

Part 1 book "Marks' basic medical biochemistry - A clinical approach" includes content: Metabolic fuels and dietary components; the fed or absorptive state; water, acids, bases, and buffersm; structures of the major compounds of the body; amino acids in proteins; structure function relationships in proteins; enzymes as catalysts; regulation of enzymes; relationship between cell biology and biochemistry; cell signaling by chemical messengers.

382p oursky07 24-10-2023 8 2   Download

Cytokinins (CKs) are considered one of the critical phytohormones with an important role in plant response to abiotic stresses. One of the key enzymes in regulating CK levels is CK oxidase/dehydrogenase (CKX), which catalyzes the irreversible CK degradation.

10p vimulcahy 18-09-2023 4 3   Download

Dopamine β-hydroxylase (DBH) is a critical enzyme in the biosynthesis of catecholamines. This enzyme’s role in neuroendocrine regulation is well known, but there are some indications that it may also modulate reproduction and endocrine in mammals and birds.

9p vinarcissa 21-03-2023 2 1   Download

The human Aldoketoreductase 1B10 gene (AKR1B10) encodes one of the enzymes belonging to the family of aldoketoreductases and may be involved in detoxification of nutrients during digestion. Further, AKR1B10 mRNA (messenger ribonucleic acid) expression was diminished in brain regions potentially involved in the regulation of eating behavior in rats which are more sensitive to cocaine and alcohol.

8p vinarcissa 21-03-2023 3 1   Download

The aim of this work was to understand involvement of PARylation in inducing enzymatic antioxidant defence and alternative electron sinks in response to salinity. For this purpose A. thaliana plants were treated with 3-aminobenzamide (3-AB), which is a PARP inhibitor, in the presence of 100 mM NaCl. The 3-AB treatment induced plant fresh weight under control and salinity conditions. Moreover, 100 mM NaCl + 3-AB treated plants had lower lipid peroxidation when compared to 100 mM NaCl group indicating mitigation of oxidative stress.

13p lyhuyenthu 31-01-2023 2 2   Download

UBE2O as an atypical ubiquitin-conjugating enzyme possesses an E2-E3 hybrid enzyme activity. It can regulate substrate levels or transcriptional activities by cooperating with other E3 ubiquitin ligases or forming homomeric complexes displaying intrinsic E2 and E3 activities. UBE2O controls the quality of cell proteome including protein degradation, modification, transport and location.

9p lyhuyenthu 31-01-2023 5 2   Download