Established therapeutic treatment
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Established for more than 75 years, Ebook The Washington manual of medical therapeutics, 36th edition, provides concise, high-yield content that reflects today’s fast-changing advances in medical technology and therapeutics. In one convenient, portable resource, you’ll find complete coverage of every area of medicine and the core subspecialties—all at your fingertips for quick review and reference. Discover why housestaff and faculty worldwide depend on this best-selling resource for day-to-day clinical practice in internal medicine.
3623p vimeyers 29-05-2024 4 2 Download
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Clear cell renal cell carcinoma (CCRCC) is a common tumor of the urological system for which surgery is the preferred treatment, but there is a lack of therapeutic options after surgery. This study aims to explore the biological role of GNG7 on CCRCC from a genetic perspective.
16p vioracle 29-09-2023 5 2 Download
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Deep vein thrombosis with arteriovenous fistulas is rare, with few therapeutic options available for chronic-phase deep vein thrombosis. Moreover, the effectiveness of endovascular treatment for chronic-phase deep vein thrombosis with arteriovenous fistulas has not been established.
5p vigamora 23-05-2023 3 2 Download
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Pancreatic cancer is one of the most lethal tumors. The aim of this study is to provide an effective therapeutic discovery platform for pancreatic cancer by establishing and characterizing patient-derived organoids (PDOs).
12p vikolindagrabar 27-07-2022 2 1 Download
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The aim of this study was to establish precision-cut bovine udder slices (PCBUS) as an in-vitro-model to investigate pathophysiological processes in the early phase of mastitis in order to have the possibility to investigate new therapeutic approaches for the treatment of such udder inflammation in later studies. Furthermore, this model should contribute to substitute in-vivo-experiments.
9p vidarwin 23-02-2022 7 1 Download
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Cytotoxic chemotherapy combinations and targeted agents represent established treatment concepts in advanced pancreatic neuroendocrine tumors (PNETs). However, response rates, side effects and outcome data strongly vary among these therapeutic approaches.
9p vimahuateng 26-11-2021 4 1 Download
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Apical periodontitis (AP) is essentially an inflammatory disease of microbial etiology primarily caused by infection of the pulp and root canal system. Variation of the bacterial communities caused by AP, as well as their changes responding to dental therapy, are of utmost importance to understand the pathogensis of the apical periodontitis and establishing effective antimicrobial therapeutic strategies.
11p visilicon2711 20-08-2021 12 1 Download
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Although beneficial effects of exercise in the management of knee osteoarthritis (OA) have been established, only 14 -18% of patients with knee OA receive an exercise from their primary care provider.
11p viannito2711 20-04-2021 11 1 Download
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Lung transplantation is a well-established treatment for end-stage non-cystic fibrosis bronchiectasis (BR), though information regarding outcomes of transplantation remains limited. Our results of lung transplantation for Br are reported here.
8p vimaine2711 26-03-2021 9 2 Download
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Shoulder pain of musculoskeletal origin is the main cause of upper limb pain of non-traumatic origin. Despite being one of the most common reasons for consultation, there is no established protocol for treatment due to the complexity of its etiology.
11p vitennessee2711 02-02-2021 7 2 Download
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The periprosthetic joint infection (PJI) is a severe complication in the field of arthroplasty. Despite the rising number of primary joint replacements, no unified therapeutic standard has been established for the treatment of PJI yet.
8p vimariana2711 22-12-2020 10 1 Download
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Patients with advanced endocrine cancers, such as adrenocortical carcinoma and medullary thyroid carcinoma, have few well-validated therapeutic options. Pre-clinical studies have suggested potential activity of imatinib in these tumors. We therefore sought to establish a safe, novel treatment regimen combining imatinib with cytotoxic chemotherapy for future study in endocrine cancers.
6p vilisa271 22-09-2020 18 1 Download
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The defects in DNA repair genes are potentially linked to development and response to therapy in medulloblastoma. Therefore the purpose of this study was to establish the spectrum and frequency of germline variants in selected DNA repair genes and their impact on response to chemotherapy in medulloblastoma patients.
11p vimale2711 21-08-2020 9 1 Download
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Approximately 250 million people worldwide are chronically infected with hepatitis B virus (HBV) and more than half of the hepatocellular carcinoma (HCC) cases are attributed to this infection. As HCC has a high mortality rate, and current treatment options are remarkably limited, the development of new therapeutic treatment strategies is warranted.
11p vimale2711 21-08-2020 7 1 Download
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The increasing incidence and poor outcome associated with malignant pleural effusion (MPE) requires finding an effective treatment for this disease. Inhibitory B7-H4 is expressed in many different human cancers but its role in malignant pleural tissue has yet to be established.
6p vimanama2711 30-07-2020 9 2 Download
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Cancer immunotherapy is a type of therapy that uses the body's immune system to prevent, control, and eliminate cancers. The cancer cells on their surface often express the tumor antigens, which are targeted by the immune response components. The past decade has witnessed immunotherapy as an appealing and attractive strategy that established a strong pillar to fight various types of malignancies (Subramaniam et al., 2016). The therapeutic and prophylactic approaches of cancer immunotherapies have been tried against different types of cancers both in human and Veterinary medicine.
14p angicungduoc6 22-07-2020 10 1 Download
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The gut micro flora plays vital role in health status of the host. Human physiology and nutrition are greatly affected by the majority of microbes living in the gut. The most dominant phyla, making up to 90 percent of the total microbial population in humans are Bacteroidetes and Firmicutes followed by Actinobacteria Proteobacteria, Tenericutes, and Verrucomicrobia.
14p cothumenhmong3 22-02-2020 43 1 Download
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Walking ability is a priority for many children with cerebral palsy (CP) and their parents when considering domains of importance regarding treatment interventions. Partial body-weight supported treadmill training has become an established therapeutic treatment approach to address this demand.
9p videshiki2711 19-02-2020 10 0 Download
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Perinatal asphyxia and resulting hypoxic-ischemic encephalopathy is a major cause of death and longterm disability in term born neonates. Up to 20,000 infants each year are affected by HIE in Europe and even more in regions with lower level of perinatal care. The only established therapy to improve outcome in these infants is therapeutic hypothermia.
10p virome2711 13-01-2020 28 0 Download
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In a semi-residential setting where children switch daily between treatment and home, establishment of a strong parent-team alliance can be a challenge. The development of alliance with parents and the symptoms of the child might be strengthened by a structured investment of treatment team members.
11p vimoskva2711 30-12-2019 16 0 Download