Evans blue dye

Increasing industrialization and urbanization result in the discharge of waste to the environment, which in turn creates more pollution. Environmental biotechnology is constantly expanding its efforts in the biological treatment of colored textile effluents, which is an environmental friendly and low cost alternative to physico-chemical decomposition processes.

8p angicungduoc6 20-07-2020 11 1   Download

Since it is known that serum albumin-bound dyes can cross the blood-brain barrier (BBB) after ischemia, Evans Blue dye is commonly used to assess BBB disruption because of its rapid binding to serum albumin. In addition, indocyanine green (ICG), a clinically available dye, binds to serum proteins that could also be used for assessment of BBB impairment.

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Evans blue dye (EBD) is the most common indicator to analyze the extent of blood-brain barrier (BBB) breakdown in several neurological disease models. However, the high-dose of EBD (51.9 mg/kg) is usually required for visualization of blue color by the human eye that brings potential safety issues.

7p vinasaki2711 12-11-2019 12 1   Download