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Evolutionary potential
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Evolutionary models of breast cancer progression differ on the extent to which metastatic potential is pre-encoded within primary tumors. Although metastatic recurrences often harbor putative driver mutations that are not detected in their antecedent primary tumor using standard sequencing technologies, whether these mutations were acquired before or after dissemination remains unclear.
19p
vicwell
29-02-2024
4
2
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Ebook "Advances in endophytic research" is an attempt to review the recent development in the understanding of microbial endophytes and their potential biotechnological applications. This is a collection of literature authored by noted researchers having signatory status in endophytic research and summarizes the development achieved so far, and future prospects for further research in this fascinating area of research.
460p
manmanthanhla0201
26-02-2024
4
1
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Ebook "The bonobos: Behavior, ecology, and conservation" focuses on scientific research. Behavioral studies in captivity propose to answer why bonobos have some unique characteristics such as high social status of females and flexible social relationships. The outcomes present important aspects to be investigated in running field studies. In the wild, analysis of population genetics across the bonobo's distribution range illuminates the species' evolutionary path and contributes to a global management plan.
333p
tachieuhoa
28-01-2024
6
2
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In ebook "Plant-environment interactions: From sensory plant biology to active plant behavior" documents a paradigm shift that is currently underway in the plant sciences. In the last two or three decades, plants have been unmasked as being very sensitive organisms that monitor and integrate large numbers of abiotic and biotic parameters from their environment. The obvious conservation that occurs throughout evolution means that action potentials provide both plants and animals with evolutionary advantages that are crucial to their adaptive behavior and survival.
313p
tachieuhoa
28-01-2024
9
2
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In ebook "Fencing for conservation: Restriction of evolutionary potential or a riposte to threatening processes?" the conflict between increasing human population and biodiversity conservation is one of the IUCN’s key threatening processes. Conservation planning has received a great deal of coverage and research as a way of conserving biodiversity yet, while theoretically successful, it has never been tested. Simple lines on maps to illustrate conservation areas are unlikely to be successful in the light of human encroachment.
331p
tachieuhoa
28-01-2024
4
2
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Defining hidden genetic diversity within species is of great significance when attempting to maintain the evolutionary potential of natural populations and conduct appropriate management. Our hypothesis is that isolated (and eventually small) wild animal populations hide unexpected genetic diversity due to their maintenance of ancient polymorphisms or introgressions.
9p
vinarcissa
21-03-2023
3
1
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Identification of genetic mechanisms and idiosyncrasies at the breed-level can provide valuable information for potential use in evolutionary studies, medical applications, and breeding of selective traits. Here, we analyzed genomic data collected from 136 Korean Native cattle, known as Hanwoo, using advanced statistical methods.
13p
vinarcissa
21-03-2023
7
1
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Misidentifications between exploited species may lead to inaccuracies in population assessments, with potentially irreversible conservation ramifications if overexploitation of either species is occurring.
13p
vinarcissa
21-03-2023
2
1
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The long introns of mammals are pools of evolutionary potential due to the multiplicity of sequences that permit the acquisition of novel exons. However, the permissibility of genes to this type of acquisition and its influence on the evolution of cell regulation is poorly understood.
13p
vigalileogalilei
27-02-2022
10
1
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Single nucleotide variants (SNVs) in intronic regions have yet to be systematically investigated for their diseasecausing potential. Using known pathogenic and neutral intronic SNVs (iSNVs) as training data, we develop the RegSNPs-intron algorithm based on a random forest classifier that integrates RNA splicing, protein structure, and evolutionary conservation features.
16p
vielonmusk
30-01-2022
20
0
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The mouse genome is replete with retrotransposon sequences, from evolutionarily young elements with mutagenic potential that must be controlled, to inactive molecular fossils whose sequences can be domesticated over evolutionary time to benefit the host genome.
4p
vialfrednobel
29-01-2022
12
0
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How species can adapt to abrupt environmental changes, particularly in the absence of standing genetic variation, is poorly understood and a pressing question in the face of ongoing climate change.
26p
viarchimedes
26-01-2022
14
0
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Staphylococcus argenteus and S. schweitzeri, were recently proposed as novel species within S. aureus complex (SAC). S. argenteus has been reported in many countries and can threaten human health. S. schweitzeri has not been associated with human infections, but has been isolated from non-human primates. Questions regarding the evolution of pathogenicity of these two species will remain elusive until an exploratory evolutionary framework is established.
17p
vilarryellison
29-10-2021
10
1
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Powdery mildews are biotrophic pathogenic fungi infecting a number of economically important plants. The grass powdery mildew, Blumeria graminis, has become a model organism to study host specialization of obligate biotrophic fungal pathogens. We resolved the large-scale genomic architecture of B. graminis forma specialis hordei (Bgh) to explore the potential influence of its genome organization on the co-evolutionary process with its host plant, barley (Hordeum vulgare).
23p
vibeauty
23-10-2021
12
0
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The genetics underlying body mass and growth are key to understanding a wide range of topics in biology, both evolutionary and developmental. Body mass and growth traits are affected by many genetic variants of small effect. This complicates genetic mapping of growth and body mass. Experimental intercrosses between individuals from divergent populations allows us to map naturally occurring genetic variants for selected traits, such as body mass by linkage mapping.
12p
vibeauty
23-10-2021
8
0
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Abiotic stresses due to climate change pose a great threat to crop production. Heat shock transcription factors (HSFs) are vital regulators that play key roles in protecting plants against various abiotic stresses.
13p
visilicon2711
20-08-2021
11
1
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Magnetotactic bacteria (MTB) are ubiquitous in natural aquatic environments. MTB can produce intracellular magnetic particles, navigate along geomagnetic field, and respond to light. However, the potential mechanism by which MTB respond to illumination and their evolutionary relationship with photosynthetic bacteria remain elusive.
13p
visilicon2711
20-08-2021
7
1
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Sporobolomyces pararoseus is regarded as an oleaginous red yeast, which synthesizes numerous valuable compounds with wide industrial usages. This species hold biotechnological interests in biodiesel, food and cosmetics industries. Moreover, the ballistospores-shooting promotes the colonizing of S. pararoseus in most terrestrial and marine ecosystems.
11p
vijeeni2711
24-07-2021
14
0
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Recent experimental work has shown that the evolutionary dynamics of bacteria expanding across space can differ dramatically from what we expect under well-mixed conditions. During spatial expansion, deleterious mutations can accumulate due to inefficient selection on the expansion front, potentially interfering with and modifying adaptive evolutionary processes.
11p
vijeeni2711
24-07-2021
12
0
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Micrococcus luteus is a group of actinobacteria that is widely used in biotechnology and is being thought as an emerging nosocomial pathogen. Here, comparative genomics, phylogenomics, and genome-wide association studies were used to investigate the genomic diversity, evolutionary history, and the potential ecological differentiation of the species.
14p
vilichoo2711
23-06-2021
14
1
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