Experimental seizures models

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2-[(3-Aminoalkyl-(alkaryl-,aryl-))-1 H-1,2,4-triazol-5-yl]anilines: Synthesis and anticonvulsant activity

The presented work is devoted to the development of synthesis methods for novel 2-[(3-aminoalkyl-(alkaryl-, aryl-))-1H -1,2,4-triazolo]anilines. Abovementioned compounds were obtained via hydrazinolysis (Ing-Manske procedure) and acid hydrolysis of corresponding N -acylated{([1,2,4]triazolo[1,5- c ]quinazolin-2-yl)alkyl-(alkaryl-, aryl-)}amines. The regioselectivity of hydrazinolysis and hydrolysis were established. The features of spectral characteristics were studied and discussed.

10p tudichquannguyet 29-11-2021 10 1 Download