Extensively described
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We designed this study based on both a physician practice survey and real-world patient data to: (1) evaluate clinical management practices in extensive-stage small cell lung cancer (ES-SCLC) among medical centers located across France; and (2) describe first-line treatment patterns among patients with ES-SCLC following the introduction of immunotherapy into clinical practice.
11p vishanshan 27-06-2024 1 1 Download
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This paper is organized as follows. In Section 2, we briefly describe the model including the particle content and the symmetry. In Section 3, we focus on the scalar particles and derive their interaction terms. In Section 4, we investigate the decay channel of a new scalar to a pair of the 125 GeV Higgs bosons. Finally, the conclusion is presented in Section 5.
8p viambani 18-06-2024 4 1 Download
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Now in its 6th edition, the best selling book on MVC is now updated for ASP.NET Core MVC. It contains detailed explanations of the new Core MVC functionality which enables developers to produce leaner, cloud optimized and mobile-ready applications for the .NET platform. This book puts ASP.NET Core MVC into context and dives deep into the tools and techniques required to build modern, cloud optimized extensible web applications. All the new MVC features are described in detail and the author explains how best to apply them to both new and existing projects.
1031p zizaybay1104 29-05-2024 6 4 Download
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In ebook "Prion proteins (Topics in current chemistry, Volume 305)" we have assembled a set of chapters highlighting various aspects of prion diseases in humans and animals which show the intriguing features of both physiological and pathogenic PrP conformers. In addition, a wide spectrum of methodological approaches are described, ranging from in silico, chemical, and in vitro approaches to animal models, to illustrate the elaborate and extensive technology established in the prion field, allowing the analysis of disease mechanisms and the development of diagnostic and therapeutic strategies.
308p manmanthanhla0201 26-02-2024 11 1 Download
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Details of improved gait ability after wide resection of soft tissue sarcomas that necessitate removal of portions of the quadricep muscle have not yet been reported. We describe a patient with improved gait ability following a rehabilitation program after wide resection of a soft tissue sarcoma that included four components of the quadricep muscle.
7p vitiki 30-01-2024 2 2 Download
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Ebook "Acetic acid bacteria: Fundamentals and food applications" written by leading international authorities in the field, covers all the basic and applied aspects of acetic acid bacteria. It describes the importance of acetic acid bacteria in food industry by giving information on the microbiological properties of fermented foods as well as production procedures. Special attention is given to vinegar and cocoa, which are the most familiar and extensively used industrial applications of acetic acid bacteria.
359p lucchinguyen 28-12-2023 6 2 Download
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Damaging alterations in the BRCA1 gene have been extensively described as one of the main causes of hereditary breast and ovarian cancer (HBOC).BRCA1 alterations can lead to impaired homologous recombination repair (HRR) of double-stranded DNA breaks, a process which involves the RING, BRCT and coiled-coil domains of the BRCA1 protein.
13p vischultz 20-10-2023 1 1 Download
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Thyroid cancer (TC) overall survival at 5 years was estimated at 97% in mainland France over 2010–2015. Its prognosis is known to be affected by patient age, tumor histology, size, and extension. This study aims to describe overall survival of thyroid cancer patients diagnosed between 2008 and 2018 in Martinique.
13p vioracle 29-09-2023 4 2 Download
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Chapter 1 first introduces the systems development life cycle (SDLC), the fundamental four-phase model (planning, analysis, design, and implementation) common to all information system development projects. Second, it describes the evolution of system development methodologies. Third, the chapter overviews object-oriented systems analysis and design and describes the Unified Process and its extensions. Finally, the chapter closes with a discussion of the roles and skills necessary within the project team.
38p abcxyz123_04 30-03-2020 45 3 Download
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Paper "Numerical homogenization technique for a strain-limiting nonlinear elasticity model" describe a numerical homogenization technique for a two-dimensional nonlinear equation emerging from strainlimiting elasticity.
3p nhanchienthien 25-07-2023 5 3 Download
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Molecular diagnosis of Inherited Retinal Dystrophies (IRD) has long been challenging due to the extensive clinical and genetic heterogeneity present in this group of disorders. Here, we describe the clinical application of an integrated next-generation sequencing approach to determine the underlying genetic defects in a Spanish family with a provisional clinical diagnosis of autosomal recessive Retinitis Pigmentosa (arRP).
11p vinarcissa 21-03-2023 1 1 Download
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The purpose of this research was to investigate the technological feasibility of biological filtration process for Mn control in Lorne WTP. This thesis consists of eight chapters. Project background and research objectives are described in Chapter 1. Chapter 2 presents an extensive literature review covering the nature of manganese, manganese analytical methods, manganese control methods, the nature of MOB and biological control of Mn in drinking water treatment. The materials and methods used throughout the experimental investigation for this study are described in Chapter 3.
119p runthenight04 02-02-2023 4 2 Download
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This paper presents an extension to a point kinetics model of fissile solution undergoing a transient through the development and addition of correlations which describe neutronics and thermal parameters and physical models.
9p vironald 15-12-2022 7 4 Download
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This paper describes the development and evaluation of a Vietnamese statistical speech synthesis system using the average voice approach. Although speaker-dependent systems have been applied extensively, no average voice based system has been developed for Vietnamese so far.
6p vichristinelagarde 04-07-2022 10 2 Download
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Left ventricular-arterial coupling (VAC), defined as the ratio of effective arterial elastance (Ea) to left ventricular end-systolic elastance (Ees), has been extensively described as a key determinant of cardiovascular work efficacy. Previous studies indicated that left ventricular-arterial uncoupling was associated with worse tissue perfusion and increased mortality in shock patients.
11p viisaacnewton 26-04-2022 9 1 Download
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The authors report a case of keratinized squamous cell carcinoma (SCC) in a 14-year-old dog with extensive cranial bone invasion. To our knowledge, this is the first description of such a case of cranial keratinized SCC with aggressive generalized osteolysis described in a dog.
8p vidarwin 23-02-2022 9 1 Download
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We describe a highly sensitive, quantitative, and inexpensive technique for targeted sequencing of transcript cohorts or genomic regions from thousands of bulk samples or single cells in parallel. Multiplexing is based on a simple method that produces extensive matrices of diverse DNA barcodes attached to invariant primer sets, which are all pre-selected and optimized in silico.
16p vielonmusk 30-01-2022 21 0 Download
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A carbonate build-up, 12 m thick, was formed with some interruptions, through the middle Pleistocene period. For this study, two travertine sections (F and D) were extensively used to figure out palaeoenvironmental and palaeoclimatic proxies. The main precipitation cycles, separated by palaeosol levels, have been described and interpreted from a sedimentological perspective. The carbonate deposits consist of shrubs, crystalline crust, reed, laminated (micritic), pisoids, oncoids, calcite thin rafts and coated gas bubbles, lithoclasts, and palaeosol levels.
19p tanmocphong 29-01-2022 6 1 Download
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Transdifferentiation describes transformation in vivo of specialized cells from one lineage into another. While there is extensive literature on forced induction of lineage reprogramming in vitro, endogenous mechanisms that govern transdifferentiation remain largely unknown.
27p viarchimedes 26-01-2022 11 1 Download
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This report describes one case of anesthetic management about surgical resection of a malignant phaeochromocytoma with tumor extension into vena cava and right atrium in a patient. Report for anesthetic management is limited in these patients under surgical resection until now.
6p vizhangzhidong 29-12-2021 11 0 Download