Fatty acid binding proteins

Fatty acid synthase (FASN) expression is associated with a more aggressive breast cancer phenotype and is regulated downstream of receptor tyrosine kinase (RTK) signaling pathways. Recently, post transcriptional regulation of lipogenic transcripts have been demonstrated as being mediated downstream of serine-arginine rich protein kinase 2 (SRPK2), which acts to phosphorylate serine-arginine rich splicing factors (SRSFs), resulting in RNA binding and various RNA regulatory processes.

13p vialfrednobel 23-12-2023 5 3   Download

Differentiation of Immortalized Human Bone Marrow Mesenchymal Stromal Cells - hTERT (iMSC3) into adipocytes is in vitro model of obesity. In our earlier study, rosiglitazone enhanced adipogenesis particularly the brown adipogenesis of iMSC3.

18p vihagrid 30-01-2023 6 3   Download

The required fluid volume differs among patients with septic shock. Enterocyte injury caused by shock may increase the need for fluid by triggering a systematic inflammatory response or an ischemia-reperfusion injury in the presence of intestinal ischemia/necrosis. This study aimed to evaluate the association between enterocyte injury and positive fluid balance in patients with septic shock.

8p viisaacnewton 26-04-2022 12 1   Download

The required fuid volume difers among patients with septic shock. Enterocyte injury caused by shock may increase the need for fuid by triggering a systematic infammatory response or an ischemia-reperfusion injury in the presence of intestinal ischemia/necrosis. This study aimed to evaluate the association between enterocyte injury and positive fuid balance in patients with septic shock.

8p vidietmarhopp 29-12-2021 7 0   Download

Nghiên cứu này tập trung vào việc tạo dòng gen, phân tích đặc tính, sự phân bố ở các mô và dự đoán tế bào B sinh miễn dịch của gen FABP ở S. mekongi. Điều này làm cơ sở cho việc nghiên cứu phát triển vắc-xin chống lại S. mekongi cũng như là giải pháp bền vững để phòng bệnh sán máng trong tương lai.

13p vimackenziebezos 29-11-2021 8 1   Download

Tạp chí Nghề cá sông Cửu Long: Số 19/2021 trình bày các nội dung chính sau: Một số đặc điểm môi trường sống và phân bố của ngao móng tay chúa liên hệ đến hướng phát triển sản xuất giống và nuôi thương phẩm; Đánh giá hiện trạng nuôi cá dứa (Pangasius sp.) ở huyện Cần Giờ, thành phố Hồ Chí Minh; Đặc tính phân tử và phân bố mô bệnh học của gene FABP (fatty acid binding protein) ở sán máng Schistosoma Mekong;... Mời các bạn cùng tham khảo để nắm nội dung chi tiết.

88p vimackenziebezos 29-11-2021 28 4   Download

The results showed that fabp10a gene was not strongly expressed in all 3 types of tissues; fabp3 gene was most strongly expressed in liver tissue and fabp7 was highly up-regulated in brain tissue. The results of this study provide a resource for further research on the function of fabp genes and their genetic diversity in striped catfish.

12p spiritedaway36 25-11-2021 7 1   Download

With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon feeds has reduced the content of these beneficial LC-HUFA.

14p vijeeni2711 30-06-2021 10 1   Download

The aim of this study was to assess the association of lung function with serum fatty-acid binding protein 4 (FABP4) in apparently healthy Korean adults. Methods: In 495 participants in a health screening program, Force Exploratory Volume (FEV) 1 and Forced Vital Capacity (FVC) were assessed with standard spirometry.

8p vimaine2711 26-03-2021 8 2   Download

A major obstacle in the use of retinoid therapy in cancer is the resistance to this agent in tumors. Retinoic acid facilitates the growth of mammary carcinoma cells which express high levels of fatty acid-binding protein 5 (FABP5). This protein delivers retinoic acid to peroxisome proliferator-activated receptor β/δ (PPARβ/δ) that targets genes involved in cell proliferation and survival.

14p vilisa271 22-09-2020 14 0   Download

Renal cell carcinomas (RCCs) overexpress fatty acid binding protein 7 (FABP7). We chose to study the TUHR14TKB cell line, because it expresses higher levels of FABP7 than other cell lines derived from renal carcinomas (OS-RC-2, 786-O, 769-P, Caki-1, and ACHN).

8p vimale2711 21-08-2020 10 2   Download

To identify potential therapeutic target in clear cell renal cell carcinoma (ccRCC), we performed a transcriptome analysis. Our analysis showed that fatty acid binding protein 7 (FABP7) has the highest mean differential overexpression in ccRCC compared to normal kidney. We aimed to investigate the significance of FABP7 in ccRCC.

11p vimanila2711 29-06-2020 5 3   Download

Non-muscle invasive bladder cancers (NMIBC: pTa, pT1) are characterised by a high risk of recurrence and/or progression. Identification of prognostic markers is needed to improve both diagnosis and management of the disease.

13p viputrajaya2711 22-06-2020 8 0   Download

Necrotizing enterocolitis (NEC) is associated with significant morbidity and mortality. Serum biomarkers to aid diagnosis, such as intestinal fatty acid binding protein (IFABP) and calprotectin, are actively being investigated; however, the normative values of these markers among healthy premature and term infants remains unknown.

7p viorochimaru2711 29-05-2020 9 1   Download

Biodiesel production using cyanobacteria is a promising alternative to fossil fuels. In this study we created a transposon library of Synechococcus elongatus PCC 7942 in order to identify novel gene targets for enhanced fatty acid and hydrocarbon production.

13p viuchiha2711 21-04-2020 6 1   Download

Adipocyte fatty acid-binding protein (A-FABP) is a cardiometabolic predictor of cardiovascular (CV) disease in humans. We evaluated the association between serum A-FABP levels and future CV events in patients with coronary artery disease (CAD).

7p vihasaki2711 12-11-2019 10 0   Download

Nghiên cứu này tiến hành phân tích đa hình di truyền các gen liên quan tính trạng kinh tế H-FABP (Heart Fatty Acid Binding Protein gene), LIF (Leukocyte Inhibitory Factor gene), MYOG (Myogenin gene), RYR1 (Ryanodine Receptor 1 gene) bằng phương pháp PCR-RFLP trên đối tượng là dòng lợn lai 2 máu Yorkshire x Landrace được nuôi tại Trại Chăn nuôi thực nghiệm Hòa An thuộc Đại học Cần Thơ.

7p cathydoll3 14-02-2019 52 0   Download

H-FABP (heart type fatty acid binding protein) là một loại men tim mới dùng trong chẩn đoán nhồi máu cơ tim cấp (NMCTC) đã được sử dụng tại nhiều quốc gia. Đây là protein có trọng lượng phân tử thấp, có nhiệm vụ vận chuyển axít béo từ màng tế bào đến ty lạp thể cần thiết cho quá trình oxy hóa. So với các men tim CK-MB, troponin, myoglobin được dùng trong chẩn đoán NMCTC hiện nay, H-FABP chứng minh được khả năng vượt trội về độ nhạy và độ đặc hiệu từ những giờ đầu (0 - 3 giờ) sau cơn đau ngực. H-FABP còn có ý nghĩa trong việc chẩn đoán hoại tử cơ tim sớm (3 - 6 giờ) trong NMCTC.

6p jangni4 20-04-2018 53 1   Download

 The intestinal fatty acid-binding protein (I-FABP) shows binding specificity for long-chain fatty acids and is proposed to be involved in uptake of dietary fatty acids and their intracellular transport. We have determined the sequence of the gene encoding I-FABP in zebrafish. The zebrafish I-FABP gene contains four exons interrupted by three introns. Radiation hybrid mapping assigned the I-FABP gene to linkage group 1. A 924 bp sequence 5Vupstream of the initiation codon in the I-FABP gene contained several putative cis-acting regulatory elements.

8p vankim10a11 08-06-2015 41 3   Download

We have determined the cDNA nucleotide sequence, deduced the amino acid sequence and defined the gene structure for the cellular heart-type (H-FABP) or fatty acid-binding protein 3 (FABP3) from zebrafish. The zebrafish FABP3 exhibited the greatest amino acid sequence identity to fish andmammalian heart-type FABPs. 3¢RACE and 5¢ RLM-RACE mapped two alternative polyadenylation sites and three transcription start sites, respectively.

12p tumor12 20-04-2013 33 1   Download