Field efficacy
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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine.
301p vimeyers 29-05-2024 4 2 Download
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Part 2 book "Fish vaccines, health management for sustainable aquaculture" includes content: Role of adjuvants in vaccination studies, development of mucosal adjutants for fish vaccination, biotechnological approaches to vaccines, safety and efficacy of vaccines in aquaculture, mass vaccination in aquaculture - possibilities and limitations, development of fish vaccines - challenges and future perspectives, fish vaccination - how close are the fish farmers, fish vaccine - from field to development.
144p oursky05 20-09-2023 7 2 Download
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Part 2 book "Fish vaccines" includes content: Fish vaccines - The regulatory process and requirements from the laboratory bench to a final commercial product, including field trials; methods for measuring efficacy, safety and potency of fish vaccines; potential of diva vaccines for fish.
74p oursky05 20-09-2023 6 1 Download
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Recent achievements in cancer therapy are the use of alternating electrical fields at intermediate frequencies (100–300 kHz) and low intensities (1–3 V/cm), which specifically target cell proliferation while affecting diferent cellular activities depending on the frequency used.
13p vioracle 29-09-2023 9 3 Download
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We aimed to evaluate the clinical efficacy and prognostic significance of intensity-modulated radiotherapy (IMRT)-based salvage concurrent chemoradiotherapy (CCRT) for patients with locoregional recurrence cervical cancer after radical hysterectomy and evaluated two salvage radiotherapy modes—regional RT (involved-field RT combined with regional lymph nodes) and local RT (involved-field RT).
10p vioracle 29-09-2023 4 2 Download
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The results revealed that entrepreneurship extracurricular activities and entrepreneurship inspiration are significantly related to students’ entrepreneurial intention. The impact of entrepreneurship education on entrepreneurial intention differ across field of study. Technical students generally get more benefits from entrepreneurship educational activities than business and economics students do. The research findings recommend some implications for fostering graduates’ entrepreneurship in emerging countries.
9p alucardhellsing 04-05-2022 13 1 Download
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These scholars all have come to a consensus that computer technology can improve learner autonomy through the abundant resources available which facilitate learner self-study. As computer technology is too broad a field for an EFL teacher to explore and figure out how it may affect learner autonomy, the researcher aims to examine the role of some technological platforms in promoting learner self-efficacy in EFL online class in a university in Vietnam.
20p hanthienngao 14-04-2022 13 1 Download
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This study was carried out under simulated field conditions to evaluate the efficacy of some bioagents and soil amendments, as a single or combined treatments, in controlling root-knot nematode Meloidogyne incognita infecting cucumber.
6p schindler 30-12-2021 11 0 Download
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Renal ischemia-reperfusion (I/R) injury, one of the drastic outcomes of renal failure and organ transplantation, tends to deteriorate over time; therefore, noninvasive therapeutic strategies will avail the progression-free survival of the patients. Magnetic field has been proposed as a noninvasive treatment strategy; however, with recent scientific advances, many controversies have arisen regarding its efficacy. Pterostilbene, a natural analog of resveratrol, was documented to be effective in treatment of I/R injuries.
13p thiencuuchu 27-11-2021 7 1 Download
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In chilli (Capsicum annuum L.) several diseases are caused from fungal, bacterial and viral origin. Among the fungal diseases, damping off caused by species of Pythium is very common in the nursery which causes about 90 per cent mortality in nurseries and fields. Present experiment was carried out in in-vitro and in-situ conditions at Department of Plant Pathology, SHUATS in Completely Randomized Design with eight treatments and three replications each.
9p chauchaungayxua12 29-07-2021 9 2 Download
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A field experiment was conducted at Anand Agricultural University, Anand during Rabi season 2019-20 to assess the bio-efficacy of various biopesticides against aphids infesting coriander. Of the nine biopesticides evaluated against aphids infesting coriander, application of tobacco decoction was found the most effective followed by ginger rhizome extract and garlic bulb extract with coriander seed yield of 449, 437, and 420 kg/ha, respectively.
10p cothumenhmong11 11-05-2021 12 2 Download
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The basis of the above facts, the present study was carried out to the termite and co-related of different doses of insecticidal treatment compared with yield in standing crop.
7p trinhthamhodang11 27-04-2021 7 1 Download
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The incidence and severity of Alternaria blight in rapeseed-mustard fields is greatly influenced by temperature, relative humidity, soil condition at the time of planting, splashing rain, wind velocity, leaf wetness and inoculum density available in the soil (Meena et al., 2004).
6p trinhthamhodang11 27-04-2021 11 1 Download
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Soybean (Glycine max L.) is an important leguminous oil seed crop among all the seed crops of country grown during rainy season. The higher incidence of weed and pests during growth period are one of the important menaces in getting higher yield of crop.A field experiment was conducted during rainy season 2019 at Agricultural Research Station, Banswara (Raj.), India to evaluate bio-efficacy of compatible tank-mix combinations of herbicide and insecticides to manage the weed and insect-pests in crop.
10p trinhthamhodang11 27-04-2021 15 2 Download
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Grain mold is economically important disease of sorghum. For Management of sorghum grain mold various chemicals were screened for efficacy and management of grain mold under field conditions. Four different fungicides viz., Hexaconazole, carbendazim, thiram+mancozeb, propiconazole and two control treatments i.e. one water spray and one absolute control were evaluated for control of sorghum grain mold.
5p trinhthamhodang11 27-04-2021 13 2 Download
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The optimal treatment for recurrent high-grade gliomas (rHGGs) remains uncertain. This study aimed to investigate the efficacy and safety of hypofractionated stereotactic radiosurgery (HSRS) as a first-line salvage treatment for in-field recurrence of high-grade gliomas.
8p vianrose2711 27-04-2021 7 2 Download
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The unprecedented efficacy of chimeric antigen receptor T (CAR-T) cell immunotherapy of CD19+ Bcell malignancies has opened a new and useful way for the treatment of malignant tumors. Nonetheless, there are still formidable challenges in the field of CAR-T cell therapy, such as the biodistribution of CAR-T cells in vivo.
10p vianrose2711 27-04-2021 9 1 Download
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Genetic alterations have been proven to be the promising biomarkers for ICI response. However, sex biases in genetic alterations have been often ignored in the field of immunotherapy, which might specially influence the anticancer immunity and immunotherapy efficacy in male or female patients.
13p vianrose2711 27-04-2021 10 1 Download
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The present study was conducted under the pot condition. Pot experiment was laid out in Completely Randomized Design (CRD) with three replications at research field of the Department of Plant Pathology, Sam Higginbottom University of Agriculture, Technology and Science, during the Rabi season of 2019-20.
9p trinhthamhodang11 27-04-2021 8 1 Download
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Damping-off of tomato incited by Pythium aphanidermatum (Edson) Fitzp. is one of the devastating diseases of tomato with substantial yield losses primarily in the nurseries than in main fields of our nation.
8p caygaocaolon11 21-04-2021 10 1 Download