Formazan compounds

Xem 1-4 trên 4 kết quả Formazan compounds

Electrochemical properties of 1,3-disubstituted methyl methoxy phenyl-5-phenylformazans and comparison with spectral properties

In this study, electrochemical behaviors of formazans were investigated. The compounds contained CH3 and OCH3 groups at the o-, m-, and p-positions of the 1-phenyl ring and an OCH3 group at the p-position of the 3-phenyl ring. Their electrochemical behaviors, such as the number of electrons transferred, diffusion coefficients, and heterogeneous rate constants, were studied by cyclic voltammetry, ultramicrodisk electrode, and chronoamperometry. Possible mechanisms were proposed based upon the data obtained.

9p langthannam 29-12-2021 11 0 Download

Synthesis of novel 5-substituted phenyl-3-(p-isopropylphenyl)-1-phenylformazan and their biological activities

Novel 1-substituted 3-(p-isopropylphenyl)-5-phenylformazans (3a–g) were synthesized and characterized by elemental analysis, 1H NMR, and FT-IR techniques and UV-visible spectroscopy. Antiproliferative activities of 3a–g against HeLa and C6 cells were determined using the BrdU cell proliferation ELISA assay. 5-Florouracil was used as the positive control. The effects of substituents (–H, –CH3, and –I) and their positions (ortho, meta, and para) on the antiproliferative activities were evaluated.

9p tudichquannguyet 29-11-2021 8 1 Download

Experimental and computational studies on the absorption properties of novel formazan derivatives

Eight novel 3-(4-(benzyloxy)phenyl)-5-(4-bromophenyl)-1-(4-substituted-phenyl)formazan (4a–4h) were synthesized by coupling of substituted phenylhydrazones with diazonium salts of 4-bromoaniline. The substituted phenylhydrazones, which are intermediate products, were obtained from the condensation of substituted phenylhydrazines with 4-(benzyloxy)benzaldehyde. All target compounds were characterized by using FTIR, 1 H NMR, 13 C NMR, LC−MS spectrometry, and elemental analysis. Absorption spectra of these compounds in solvents with different polarities were investigated thoroughly.

31p tudichquannguyet 29-11-2021 8 1 Download
Functionalized formazans: A review on recent progress in their pharmacological activities

This review provides an up to date information about the diverse pharmaceutical activities of formazans. The bibliography includes 97 references which have been published during the period from 1980 to 2013. The covered biological activities of the title compounds include antioxidant, anticonvulsant, therapeutic, anthelmintic, anti-tubercular, antiviral, anti-inflammatory, anticancer, anti-HIV, antimicrobial, antiparkinsonian, cardiovascular and antiproliferative activities.

14p trinhthamhodang1 16-11-2019 18 1 Download