Frequent exacerbations
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To evaluate changes in serum levels of some cytokines in asthma patients with frequent exacerbations. Methods: A prospective, descriptive, longitudinal study on 60 asthma patients with frequent exacerbations and 60 ones with few exacerbations, treated as outpatients at the Asthma Management Department, Hai Phong International Hospital from January 2020 to May 2023.
10p vijaychest 16-05-2024 4 1 Download
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Research on critical thinking skills has been frequently carried out, but it has not shown maximum results. This problem is exacerbated by the differences in pre-service teachers’ academic abilities. A new learning model that can improve pre-service teachers’ critical thinking skills and reduce the gap in critical thinking skills among the upper, middle, and lower academic ability pre-service teachers is needed.
12p viarnault 25-04-2024 2 1 Download
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Coronary heart disease (CHD), sarcopenia and depression are common disorders that markedly impair quality of life and impose a huge financial burden on society. They are also frequently comorbid, exacerbating condition and worsening prognosis. This study aimed to investigate the additive effect of CHD and sarcopenia on the risk of new onset depressive symptoms in older adults.
8p vinobelprisen 26-03-2022 14 4 Download
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Intra-host hepatitis C virus (HCV) populations are genetically heterogeneous and organized in subpopulations. With the exception of blood transfusions, transmission of HCV occurs via a small number of genetic variants, the effect of which is frequently described as a bottleneck.
9p vilarryellison 29-10-2021 8 1 Download
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Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are often linked to respiratory infections. However, it is unknown if COPD patients who experience frequent exacerbations have impaired humoral immunity.
7p vianthony2711 16-04-2021 11 2 Download
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Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder partially resistant to glucocorticoids. A reduced histone deacetylase (HDAC) activity has been proposed to explain this resistance. Haemophilus influenzae frequently colonizes the airways of COPD patients, where it enhances inflammation.
8p vimontana2711 05-04-2021 8 3 Download
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Chronic obstructive pulmonary disease (COPD) is a major cause of mortality worldwide. Patients with COPD frequently have systemic comorbidities that often require unscheduled hospitalization for exacerbation and deterioration of physical conditions, and can have a poor prognosis.
6p vimontana2711 05-04-2021 11 1 Download
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Cystic Fibrosis (CF) is a genetic disease with equal prevalence across sexes. However, women present worse lung function with faster function decline, earlier onset of bacterial colonization, more frequent pulmonary exacerbations (PE), greater bronchial hyper-responsiveness, and higher mortality rates after puberty than men.
4p vimontana2711 05-04-2021 5 1 Download
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Chronic obstructive pulmonary disease (COPD) patients often present considerable individual medical burden in their symptoms, limitations, and well-being that complicate medical treatment. To improve their overall health status, while reducing the number of exacerbations, a multidisciplinary approach including different elements of care is needed.
12p vimaine2711 26-03-2021 10 1 Download
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In chronic obstructive pulmonary disease, the prognosis for patients who have survived an episode of acute hypercapnic respiratory failure due to an exacerbation is poor. Despite being shown to improve survival and quality-of-life in stable patients with chronic hypercapnic respiratory failure, long-term noninvasive ventilation is controversial in unstable patients with frequent exacerbations, complicated by acute hypercapnic respiratory failure.
5p vimaine2711 26-03-2021 8 2 Download
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Severe non-allergic eosinophilic asthma (SNEA) is a rare asthma phenotype associated with severe clinical course, frequent exacerbations, and resistance to therapy, including high steroid doses. The key feature is type 2 inflammation with predominant airway eosinophilia.
12p vimaine2711 26-03-2021 10 2 Download
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Measurement of sputum is frequently used to define airway inflammatory subtypes. The venous blood cell is a reliable and simple biomarker, may be used as an alternative procedure to reflect the subtypes. For the aim of verifying the hypothesis that venous blood cell can quantify sputum inflammatory cell to access the airway subtypes in chronic obstructive pulmonary disease of acute exacerbations (AECOPD) and to ascertain the accuracy of the blood cell biomarker.
9p vimaine2711 26-03-2021 13 2 Download
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Factors associated with reduced daily physical activity (DPA) in patients with COPD are still controversial. Physical inactivity in COPD increases risk of cardiovascular disease, frequent exacerbations, reduced health status, and increased symptoms. We hypothesised that reduced DPA in patients with COPD is independent of traditional risk factors including age and spirometry.
8p vimaine2711 26-03-2021 13 2 Download
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Chronic obstructive pulmonary disease (COPD) patients with different phenotypes show different clinical characteristics. Therefore, we conducted a meta-analysis to explore the clinical characteristics between the non-exacerbator (NE) phenotype and the frequent exacerbator with chronic bronchitis (FE-CB) phenotype among patients with COPD.
10p vimaine2711 26-03-2021 8 1 Download
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Despite inhaled medications that decrease exacerbation risk, some COPD patients experience frequent exacerbations. We determined prospective risk factors for exacerbations among subjects in the COPDGene Study taking inhaled medications.
12p vimaine2711 26-03-2021 10 2 Download
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Cardiovascular disease (CVD) is a common comorbidity in chronic obstructive pulmonary disease (COPD). Cardiac troponin (cTn) elevation, indicating myocardial injury, is frequent during acute COPD exacerbations and associated with increased mortality.
8p vimaine2711 26-03-2021 11 2 Download
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Asthma exacerbations are frequent in patients with severe disease. This report describes results from two retrospective cohort studies describing exacerbation frequency and risk, emergency department (ED)/hospital re-admissions, and asthma-related costs by asthma severity in the US and UK.
11p vimaine2711 26-03-2021 10 2 Download
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Influenza is a frequent cause of exacerbations of chronic obstructive pulmonary disease (COPD). Exacerbations are associated with worsening of the airflow obstruction, hospitalisation, reduced quality of life, disease progression, death, and ultimately, substantial healthcare-related costs.
15p vimaine2711 26-03-2021 5 2 Download
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By WHO forecasts, a further increase in the prevalence and mortality of COPD among people of working age is predicted, due to uncontrolled environmental pollution, a tobacco pandemic, an increase in the level of allergens and a genetic predisposition. In chronization and progression of COPD, there is a violation of cellular and humoral immunity, production of pro-inflammatory cytokines of phagocytic cell activity that contribute to the persistence of the inflammatory process in the lungs.
5p cothumenhmong3 22-02-2020 28 0 Download
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Multilingual applications frequently involve dealing with proper names, but names are often missing in bilingual lexicons. This problem is exacerbated for applications involving translation between Latin-scripted languages and Asian languages such as Chinese, Japanese and Korean (CJK) where simple string copying is not a solution. We present a novel approach for generating the ideographic representations of a CJK name written in a Latin script.
8p bunbo_1 17-04-2013 54 1 Download