Functional redundancy
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Genes with multiple co-active promoters appear common in brain, yet little is known about functional requirements for these potentially redundant genomic regulatory elements. SCN1A, which encodes the NaV1.1 sodium channel alpha subunit, is one such gene with two co-active promoters.
22p vibransone 28-03-2024 5 2 Download
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Lecture Database Systems - Chapter 7: Functional dependencies & Normalization for relational DBs has present the content: overview of database design process; introduction; functional dependencies; normalization; direct dependency;...
79p andromedashun 26-05-2022 14 3 Download
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Lecture Game design: Controls introduces contents such as control is in your hand, for children, MMO and FPS, what a finger can do, play a “negative response” sound effect or animation, make it clear during your training mode, assign a redundant but related function.
9p lavender2022 22-04-2022 17 4 Download
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Whole genome duplication (WGD) events have played a major role in eukaryotic genome evolution, but the consequence of these extreme events in adaptive genome evolution is still not well understood.
18p viarchimedes 26-01-2022 10 0 Download
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This study evaluated the phytoplankton communities based on functional groups to obtain information about the water quality of Lake İznik, Turkey. The phytoplankton consisted of 103 taxa, classified in 12 phytoplankton functional groups (PFGs), with dominancy of 5 species, Chrysosporum ovalisporum, Dolichospermum mendotae, Planktothrix rubescens, Fragilaria capucina, and Mougeotia sp. The Shannon–Wiener diversity index (H’) was calculated and results ranged between 0.41 and 2.47.
14p tudichquannguyet 29-11-2021 9 1 Download
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The regulatory landscape of a gene locus often consists of several functionally redundant enhancers establishing phenotypic robustness and evolutionary stability of its regulatory program. However, it is unclear what mechanisms are employed by redundant enhancers to cooperatively orchestrate gene expression.
12p viseulgi2711 31-08-2021 12 1 Download
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Auxins play key roles in the phytohormone network. Early auxin response genes in the AUX/ IAA, SAUR, and GH3 families show functional redundancy, which makes it very difficult to study the functions of individual genes based on gene knockout analysis or transgenic technology.
11p vijeeni2711 30-06-2021 18 1 Download
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The fungus Parastagonospora nodorum causes septoria nodorum blotch (SNB) of wheat (Triticum aestivum) and is a model species for necrotrophic plant pathogens. The genome assembly of reference isolate Sn15 was first reported in 2007.
16p vilichoo2711 23-06-2021 6 1 Download
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The objective function is the total weight of the structure while the strength and serviceability constraints are evaluated with nonlinear inelastic analysis. To save computational cost, an improved differential evolution (DE) algorithm is employed. Compared to the conventional DE algorithm, the proposed method has two major improvements: (1) a self-adaptive mutation strategy based on the p-best method to enhance the balance between global and local searches and (2) use of the multi-comparison technique (MCT) to reduce redundant structural analyses.
6p nguaconbaynhay12 13-06-2021 14 1 Download
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Auxin is critical to plant growth and development, as well as stress responses. Small auxin-up RNA (SAUR) is the largest family of early auxin responsive genes in higher plants. However, the function of few SAUR genes is known owing to functional redundancy among the many family members.
14p vijichea2711 28-05-2021 7 1 Download
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The glyoxylate reductase (GR) multigene family has been described in various plant species, their isoforms show different biochemical features in plants. However, few studies have addressed the biological roles of GR isozymes, especially for rice.
12p vijichea2711 28-05-2021 8 1 Download
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Protein-coding DNA sequences and their corresponding amino acid sequences are routinely used to study relationships between sequence, structure, function, and evolution. The rapidly growing size of sequence databases increases the power of such comparative analyses but it makes it more challenging to prepare high quality sequence data sets with control over redundancy, quality, completeness, formatting, and labeling.
5p vikentucky2711 26-11-2020 11 0 Download
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Much effort has been devoted to the discovery of specific mechanisms between drugs and single targets to date. However, as biological systems maintain homeostasis at the level of functional networks robustly controlling the internal environment, such networks commonly contain multiple redundant mechanisms designed to counteract loss or perturbation of a single member of the network.
14p viconnecticut2711 29-10-2020 14 1 Download
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Eqolisins are rare acid proteases found in archaea, bacteria and fungi. Certain fungi secrete acids as part of their lifestyle and interestingly these also have many eqolisin paralogs, up to nine paralogs have been recorded.
16p viconnecticut2711 28-10-2020 11 1 Download
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The consolidation of pathway databases, such as KEGG, Reactome and ConsensusPathDB, has generated widespread biological interest, however the issue of pathway redundancy impedes the use of these consolidated datasets. Attempts to reduce this redundancy have focused on visualizing pathway overlap or merging pathways, but the resulting pathways may be of heterogeneous sizes and cover multiple biological functions.
11p viconnecticut2711 28-10-2020 14 2 Download
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Sedolisins are acid proteases that are related to the basic subtilisins. They have been identified in all three superkingdoms but are not ubiquitous, although fungi that secrete acids as part of their lifestyle can have up to six paralogs.
15p viconnecticut2711 28-10-2020 13 3 Download
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Functional enrichment of genes and pathways based on Gene Ontology (GO) has been widely used to describe the results of various -omics analyses. GO terms statistically overrepresented within a set of a large number of genes are typically used to describe the main functional attributes of the gene set.
9p vicolorado2711 22-10-2020 12 0 Download
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Aberrant AKT activation is prevalent across human cancer lineages, providing an important therapeutic target. AKT comprises three isoforms that mediate critical non-redundant, even opposing functions in cancer pathophysiology.
10p vimanila2711 29-06-2020 7 0 Download
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Software testing is a major component of software development lifecycle and it’s time consuming. the testing used the particular time in testing is generally disturbed with generating the test cases and correctly testing them. although some people apply k means clustering algorithm to the test suite reduction, the algorithm is unstable and seldom considers the coverage rate of such test cases.
7p cleopatrahuynh 01-06-2020 24 0 Download
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During this paper, a very important effort is formed to propose a brand new technique to get the optimized take a look at ways from UML sequence diagram. A tailored algorithmic rule known as as Firefly algorithmic rule is employed to induce the vital ways. Firefly algorithmic rule is met heuristic and impressed from flashing behavior of fireflies.
7p cleopatrahuynh 01-06-2020 12 1 Download