Fungus Mucor circinelloides

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Growth inhibitory activities of the rhizome crude extract of Curcuma longa on the human pathogenic fungus Mucor circinelloides

Mucormycosis is an uncommon but life-threatening invasive fungal infection, mostly occurs in immunocompromised patients. Lacking the appropriate antifungal drugs is one of the reasons that lead to difficulties in the management of mucormycosis. Curcuma longa has been used traditionally and widely to treat various diseases, including fungal infections.

10p tamynhan5 10-12-2020 7 2 Download

Generation of RNAi plasmid corresponding to the m1l1 gene (ID 140500) belonging to myosin class i in the fungus Mucor circinelloides

To investigate biological roles of Myosin class I in the morphology of M. circinelloides and identify good candidates for further analyses of Mucor pathogenesis, we are going to inhibit their expression using RNAi technique. We named the two myosin class I like genes as M1L1 (ID 140500) and M1L2 (ID 116620). In the present study, we report the results of generation of RNAi plasmid to inhibit the expression of M1L1 gene.

6p koxih_kothogmih5 04-09-2020 32 2 Download