Gastrointestinal stromal tumor
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The risk category of gastric gastrointestinal stromal tumors (GISTs) are closely related to the surgical method, the scope of resection, and the need for preoperative chemotherapy. We aimed to develop and validate convolutional neural network (CNN) models based on preoperative venous-phase CT images to predict the risk category of gastric GISTs.
10p vikoch 27-06-2024 2 1 Download
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Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. Acquired functional mutations in the tyrosine-protein kinase growth factor receptor proto-oncogene (KIT) and platelet-derived growth factor-alpha gene lead to increased tyrosine kinase activity, which is considered a key factor in the pathogenesis of GIST.
14p vikoch 27-06-2024 1 1 Download
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U mô đệm đường tiêu hóa (gastrointestinal Stromal Tumor: GIST) là 1 thể u trung mô hay gặp nhất trong các khối u trung mô đường tiêu hóa xuất phát từ tế bào (TB) kẽ Cajal. Bài viết báo cáo hồi cứu ca lâm sàng GIST xuất phát từ tụy (ngoài đường tiêu hóa) hiếm gặp với mục tiêu: mô tả đặc điểm lâm sàng và cận lâm sàng, đánh giá kết quả phẫu thuật và điểm lại Y văn.
4p vioraclene 16-04-2024 4 1 Download
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Ebook "The biology of gastric cancers" represents the very first volume devoted to the subject of the basic biology of gastric cancer. Although there were major achievements 30–40 years ago in the description of the histopathology of stomach tumors and the preneoplastic conditions that preceded these lesions, it was of course the pioneering (and Nobel prize– winning) studies involving the discovery of Helicobacter pylori by Marshall and Warren that set the stage for the more recent insights on the role of chronic inflammation and cancer.
654p cotieubac1004 15-03-2024 0 0 Download
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Carney’s triad is a rare syndrome comprising gastrointestinal stromal tumor, extra-adrenal paraganglioma, and pulmonary chondroma along with newer additions of adrenal adenoma and esophageal leiomyoma. The triad is completely manifest in only 25–30% cases, with most patients presenting with two out of three parts of the syndrome.
6p vilazada 31-01-2024 4 2 Download
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Gastrointestinal stromal tumor is considered the most common mesenchymal neoplasm of the gastrointestinal tract. The majority of gastrointestinal stromal tumor cases are located in the stomach and usually affect older adults.
5p vitiki 30-01-2024 2 2 Download
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Ripretinib is a novel switch-control kinase inhibitor that inhibits KIT and PDGFRA signaling. In the INVIC‑ TUS phase 3 trial, ripretinib increased median progression-free survival and prolonged overall survival vs. placebo in ≥fourth-line advanced GIST. Here, we report prespecified analysis of quality of life (QoL) as assessed by patientreported outcome (PRO) measures and an exploratory analysis evaluating the impact of alopecia on QoL.
10p vileonardodavinci 23-12-2023 4 2 Download
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Gastrointestinal stromal tumor (GIST) is currently regarded as a potentially malignant tumor, and early diagnosis is the best way to improve its prognosis. Therefore, it will be meaningful to develop a new method for auxiliary diagnosis of this disease.
10p vileonardodavinci 23-12-2023 3 3 Download
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Primary double KIT/PDGFRA mutations are very rare in gastrointestinal stromal tumours (GISTs) but have not been comprehensively studied to date. In the present study, we investigated the clinicopathologic and genetic features of eight cases of primary double-mutant GISTs, and we reviewed the literature.
12p vischultz 20-10-2023 1 1 Download
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Gastrointestinal stromal tumors (GISTs) are non-epithelial stromal tumors that arise in the gastrointestinal tract. Pharmacological treatments for GIST are tyrosine kinase inhibitors. For metastatic disease, debulking may be helpful in reducing the tumor burden, thus increasing the effectiveness of tyrosine kinase inhibitors.
4p viintuit 26-09-2023 3 0 Download
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Gastrointestinal stromal tumors (GISTs) are a type of mesenchymal tumors. They are rare in rectum. This location is a surgical challenge due to the high morbidity after aggressive surgeries. We present the case of an 81-year-old female with a high-grade GIST treated with transvaginal excision and adjunctive therapy with imatinib.
4p viintuit 26-09-2023 4 0 Download
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Gastrointestinal stromal tumors (GISTs) are rare tumors of the GI tract that can sometimes present as a gastrointestinal bleeding source. This report describes a patient presented with upper GI bleeding secondary to a gastric GIST, which was initially detected on endoscopy.
5p viintuit 26-09-2023 3 0 Download
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Duodenal adenocarcinoma (DA), gastrointestinal stromal tumor (GIST), and pancreatic neuroendocrine tumor (PNET) are a set of rare gastrointestinal (GI) cancers characterized by nonspecific symptoms such as anemia, weight loss, and abdominal pain. We report an interesting case of DA, GIST, and PNET in a 79-year-old African American male who presented to the emergency department with syncope. The patient was tachycardic and found to have severe anemia.
5p viintuit 26-09-2023 3 0 Download
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In this study, we describe case report of 70-year-old man was admitted to our hospital because of abdominal pain over 6 months with no pathological antecedent. Abdominal ultrasound (US) reveal a omental solid mass in left lumbar region, and on CT scan show a solid mass in left lumbar region in front of the descending colon, maesuring around 50x87x133mm with well-circumscribed, slight enhance with intravenous contrast, no hemmorrage or necrosis area, no calcification and not clearly separated from small-bowel.
5p vigamora 23-05-2023 8 2 Download
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A duodenal gastrointestinal stromal tumor mimicking a pancreatic neuroendocrine tumor: A case report
Duodenal gastrointestinal stromal tumors are rare. If tumor growth is extraluminal and involves the head of the pancreas, the diagnosis of a duodenal gastrointestinal stromal tumor is difficult.
6p vigamora 23-05-2023 6 2 Download
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During neoadjuvant chemotherapy for giant gastrointestinal stromal tumors, changes in gastrointestinal stromal tumor size are rarely associated with events such as perforation and bleeding that require emergency surgery.
6p videadpool 05-05-2023 4 2 Download
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U mô đệm đường tiêu hóa (Gastrointestinal stromal tumors -GIST) có nguồn gốc từ tế bào kẽ Cajal hay tế bào giống Cajal (Cajal-like), nằm trong lớp cơ trơn của ống tiêu hóa. Bài viết trình bày ca lầm sàng u mô đệm khổng lồ của tá tràng.
3p vidudley 20-02-2023 2 1 Download
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Acquired resistance to approved tyrosine kinase inhibitors limits their clinical use in patients with gastrointestinal stromal tumor (GIST). This study investigated the safety, tolerability and efficacy of alpelisib, a phosphatidylinositol 3-kinase inhibitor, used in combination with imatinib in patients with advanced GIST who had failed prior therapy with both imatinib and sunitinib.
8p vikolindagrabar 27-07-2022 5 1 Download
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Sarcopenia predicts poor prognosis of a variety of gastrointestinal malignancies. However, there is a lack of study on the association between skeletal muscle index (SMI) and the prognosis of gastrointestinal stromal tumor (GIST).
9p viangelamerkel 27-07-2022 4 2 Download
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The prognosis of patients with gastrointestinal stromal tumors (GISTs) is generally evaluated at the time of diagnosis but does not reflect the survival dynamics of patients in the future. Therefore, the purpose of this article was to evaluate the conditional survival (CS) of Chinese patients with GISTs after radical resection.
10p vimahuateng 26-11-2021 12 1 Download