Genes and chromosomes

Part 1 book "Molecular diagnostics - Fundamentals, methods, and clinical applications" includes content: Nucleic acids and proteins; gene expression and epigenetics; nucleic acid extraction methods; resolution and detection of nucleic acids; analysis and characterization of nucleic acids and proteins; nucleic acid amplifi cation; chromosomal structure and chromosomal mutations, gene mutations; DNA sequencing.

280p muasambanhan10 06-04-2024 0 0   Download

Current computational methods on Hi-C analysis focused on identifying Mb-size domains often failed to unveil the underlying functional and mechanistic relationship of chromatin structure and gene regulation. We developed a novel computational method HiSIF to identify genome-wide interacting loci.

13p vibransone 28-03-2024 3 2   Download

Allele-specific expression (ASE) is differential expression of each of the two chromosomal alleles of an autosomal gene. We assessed ASE patterns in the human left atrium (LA, n = 62) and paired samples from the left ventricle (LV, n = 76) before and after ischemia, and tested the utility of differential ASE to identify genes associated with postoperative atrial fibrillation (poAF) and myocardial ischemia.

11p vioraclene 31-03-2024 2 2   Download

Germline chromothripsis causes complex genomic rearrangements that are likely to affect multiple genes and their regulatory contexts. The contribution of individual rearrangements and affected genes to the phenotypes of patients with complex germline genomic rearrangements is generally unknown.

14p vioraclene 31-03-2024 2 2   Download

Enabled by high-throughput sequencing approaches, epithelial cancers across a range of tissue types are seen to harbor gene fusions as integral to their landscape of somatic aberrations. Although many gene fusions are found at high frequency in several rare solid cancers, apart from fusions involving the ETS family of transcription factors which have been seen in approximately 50 % of prostate cancers, several other common solid cancers have been shown to harbor recurrent gene fusions at low frequencies.

18p vioraclene 31-03-2024 0 0   Download

Many carcinomas have recurrent chromosomal aneuploidies specific to the tissue of tumor origin. The reason for this specificity is not completely understood. Methods: In this study, we looked at the frequency of chromosomal arm gains and losses in different cancer types from the The Cancer Genome Atlas (TCGA) and compared them to the mean gene expression of each chromosome arm in corresponding normal tissues of origin from the Genotype-Tissue Expression (GTEx) database, in addition to the distribution of tissue-specific oncogenes and tumor suppressors on different chromosome arms.

16p vibransone 28-03-2024 2 2   Download

Non-invasive prenatal testing (NIPT) as a screening method for common chromosomal abnormalities such as trisomy 21, 18, and 13 has been widely adopted. In the last five years, the possibility of NIPT to detect common single-gene disorders (SGD) due to de novo mutations or paternal inherited had been reported worldwide.

8p vilarry 12-03-2024 1 1   Download

Part 1 book "Essential cell biology" includes content: Cells - The fundamental units of life, chemical components of cells energy, catalysis and biosynthesis, protein structure and function, DNA and chromosomes, DNA replication and repair, from DNA to protein - How cells read the genome, control of gene expression, how genes and genomes evolve, analyzing the structure and function of genes.

398p muasambanhan08 01-03-2024 2 1   Download

Ebook "Advances in wheat genetics: From genome to field (Proceedings of the 12th International wheat genetics symposium)" provides a comprehensive review of the forefront of wheat research, across various important topics such as germplasm and genetic diversity, cytogenetics and allopolyploid evolution, genome sequencing, structural and functional genomics, gene function and molecular biology, biotic stress, abiotic stress, grain quality, and classical and molecular breeding.

421p manmanthanhla0201 26-02-2024 2 1   Download

Part 1 book "Molecular cell biology" includes content: Life begins with cells, chemical foundations, protein structure and function, basic molecular genetic mechanisms, biomembranes and cell architecture, integrating cells into tissues, transport of ions and small molecules across cell membranes, cellular energetics, molecular genetic techniques and genomics, molecular structures of genes and chromosomes, transcriptional control of gene expression.

490p muasambanhan07 18-02-2024 2 2   Download

SMARCB1, also known as INI1, is a member of a large protein complex involved in chromatin remodeling and thus the regulation of gene expression. It is located on chromosome 22q11.2. SMARCB1 tumors have been found in various locations, including the sinonasal region, gastrointestinal tract, central nervous system (in atypical teratoid and rhabdoid tumors), and perirenal region (in malignant rhabdoid tumors) in both adults and children.

5p vitiki 30-01-2024 3 2   Download

Prader–Willi syndrome is a complex multisystem disorder due to the absent expression of paternally active genes in the Prader–Willi syndrome-critical region on chromosome 15 (15q11.2-q13). The main clinical features are hyperphagia (which frequently results in early-onset obesity), hypogonadism, developmental delays, typical behaviors (such as obsessive–compulsive tendencies, tantrums, perseveration, insistence on sameness, and rigidity), and distinctive facial features.

4p vitiki 30-01-2024 3 2   Download

Ebook "Progress in botany 67" provides readers with contents including: fascination with chloroplasts and chromosome pairing; recombination - cytoplasmic male sterility and fertility restoration in higher plants; function of genetic material - from genomics to functional markers in maize; extranuclear inheritance - gene transfer out of plastids; molecular cell biology - epigenetic gene silencing in plants;...

583p tachieuhoa 28-01-2024 4 2   Download

Part 1 book "Sex control in aquaculture" includes content: Sex control in aquaculture - concept to practice; sex determination and differentiation in fish - genetic, genomic, and endocrine aspects; epigenetics of sex determination and differentiation in fish; environmental sex determination and sex differentiation in teleosts – how sex is established; gene knockout and its principle and application in sex control of fish species,... and other contents.

410p muasambanhan04 07-01-2024 2 1   Download

Telomere dysfunction results in aneuploidy, and ongoing chromosomal abnormalities. The threedimensional (3D) nuclear organization of telomeres allows for a distinction between normal and tumor cells. On the other hand, aurora kinase genes (AURKA and AURKB) play an important role regulating the cell cycle.

11p vialfrednobel 23-12-2023 5 3   Download

Part 1 book "Alberts - Essential cell biology" includes content: Cells - the fundamental units of life; chemical components of cells; energy, catalysis, and biosynthesis; protein structure and function; DNA and chromosomes; DNA replication, repair, and recombination; from DNA to protein - how cells read the genome; control of gene expression; how genes and genomes evolve; modern recombinant DNA technology.

383p muasambanhan01 13-12-2023 4 2   Download

Part 1 book "Salmonella - Methods and protocols" includes content: Luminex® multiplex bead suspension arrays for the detection and serotyping of salmonella spp.; quantitative proteomic identification of host factors involved in the salmonella typhimurium infection cycle; determination of antimicrobial resistance in salmonella spp.; red mediated recombineering of salmonella enterica genomes; a method to introduce an internal tag sequence into a salmonella chromosomal gene,... and other contents.

129p muasambanhan01 13-12-2023 7 3   Download

Part 1 book "Genetics in medicine" includes content: Introduction, introduction to the human genome, the human genome, human genetic diversity - mutation and polymorphism, principles of clinical cytogenetics and genome analysis, the chromosomal and genomic basis of disease - disorders of the autosomes and sex chromosomes, patterns of single gene inheritance, complex inheritance of common multifactorial disorders, genetic variation in populations, identifying the genetic basis for human disease.

197p oursky09 08-11-2023 4 2   Download

Genomic alterations, including loss of function in chromosome band 11q22-23, are frequently observed in neuroblastoma, which is the most common extracranial childhood tumour. In neuroblastoma, ATM, a DNA damage response-associated gene located on 11q22-23, has been linked to tumorigenicity.

13p vischultz 20-10-2023 1 1   Download

Part 1 book "Molecular cell biology" includes content: Molecules, cells, and model organisms; chemical foundations; protein structure and function; culturing and visualizing cells 1fundamental molecular genetic mechanisms; molecular genetic techniques, biomembrane structure; genes, genomics, and chromosomes; transcriptional control of gene expression; post transcriptional gene control.

514p oursky06 17-10-2023 2 1   Download