Genes and environment

The present investigation was under taken with the objectives to estimate genetic variability, heritability and genetic advance for yield and yield contributing components of cucumber. The experimental materials for this investigation were fourteen genotypes of cucumber consisting of parthenocarpic, gynoecious and monecious germplasms crossed in line × tester mating design produced thirty three hybrids (F1). Thirty three F1 crosses along with their parents were evaluated in two environments viz.

9p angicungduoc6 22-07-2020 20 2   Download

Nuclear receptors (NRs) are ligand-regulated, DNA-binding transcription factors that function in the chromatin environment of the nucleus to alter the expression of subsets of hormone-responsive genes. It is clear that chromatin, rather than being a passive player, has a profound effect on both transcriptional repression and activation mediated by NRs.

9p research12 01-06-2013 32 2   Download

AnN-acyl-D-amino acid amidohydrolase (N-D-AAase) was identified in cell extracts of a strain, Iso1, isolated from an environment containing N-acetyl-D-methionine. The bac-terium was classified as Variovorax paradoxusby phylo-genetic analysis. The gene was cloned and sequenced. The gene consisted of a 1467-bpORF encoding a polypeptide of 488 amino acids. TheV.

11p research12 29-04-2013 44 3   Download

Multi-protein complexes are emerging as important entities of biological activity inside cells that serve to create func-tional diversity by contextual combination of gene products and, at the same time, organize the large number of different proteins into functional units. Many a time, when studying protein complexes rather than individual proteins, the bio-logical insight gained has been fundamental, particularly in cases in which proteins with no previous functional anno-tation couldbe placed intoa functional context derived from their
molecular environment. ...

9p tumor12 20-04-2013 38 2   Download

Selenium is a trace element found in freshwater and the marine environ-ment. We show that it plays a major role in spicule formation in the demo-sponge Suberites domuncula. If added to primmorphs, an in vitro sponge cell culture system, it stimulates the formation of siliceous spicules. Using differential display of transcripts, we demonstrate that, after a 72-h expo-sure of primmorphs to selenium, two genes are up-regulated; one codes for selenoprotein M and the other for a novel spicule-associated protein....

15p fptmusic 11-04-2013 32 2   Download

Neurodegenerative disorders, such as Huntington’s, Alzheimer’s, and Parkinson’s diseases, affect millions of people worldwide and currently there are few effective treatments and no cures for these diseases. Transgenic mice expressing human transgenes for huntingtin, amyloid precursor protein, and other genes associated with familial forms of neurodegenerative disease in humans provide remarkable tools for studying neurodegeneration because they mimic many of the pathological and behavioural features of the human conditions. ...

15p awards 06-04-2013 39 4   Download

Horizontal gene transfer has been a major force for genome plasticity over evolutionary history, and is largely responsible for fitness-enhancing traits, including antibiotic resistance and virulence factors. In particular, for adap-tation of prokaryotes to extreme environments, lateral gene transfer seems to have played a crucial role.

9p inspiron33 25-03-2013 41 3   Download

In the central nervous system, long-term adaptive responses to changes in the environment, such as the processes involved in learning and memory, require the conversion of extracellular stimuli into intracellular signals. Many of these signals involve the induction of gene expression.

6p galaxyss3 19-03-2013 38 4   Download

Chromatin is by its very nature a repressive environment which restricts the recruitment of transcription factors and acts as a barrier to polymerases. Therefore the complex process of gene activation must operate at two levels. In the first instance, localized chromatin decondensation and nucleosome displacement is required to make DNA accessible.

29p cosis54 05-01-2013 48 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: " A model of gene-gene and gene-environment interactions and its implications for targeting environmental

24p toshiba17 28-10-2011 47 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking...

12p thulanh14 15-10-2011 54 3   Download