Genetic engineering approaches

An approach based on anin silico analysis predicted that CYP77A4, a cytochrome P450 that so far has no identified function, might be a fatty acid-metabolizing enzyme. CYP77A4was heterologously expressed in a Saccharomyces cerevisiaestrain (WAT11) engineered for cytochrome P450 expression. Lauric acid (C12:0 ) was converted into a mixture of hydroxy-lauric acids when incubated with microsomes from yeast expressing CYP77A4.

17p vinaphone15 27-02-2013 46 2   Download

This paper presents the experiences gained from ongoing research collaboration between the School of Computer Engineering at Nanyang Technological University and the Southampton e-Science centre at the University of Southampton using a serviceoriented approach for complex engineering design optimization. The service-oriented approach enables programmatic collaboration to be realized while maintaining the autonomy of individual codes at the different institutes and organizations. In the current work, a Genetic algorithm optimization logic implemented as a Grid...

6p khangoc239 10-08-2012 52 6   Download