Germ cell
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Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–40 years, with increasing incidence worldwide. About 33~50% of the patients present with metastatic disease at diagnosis. TGCT survivors experience short- and long-term sequelae, including cancer-related fatigue (CRF).
15p vikoch 27-06-2024 2 1 Download
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Ebook "Male germline stem cells: Developmental and regenerative potential" covers many of the fundamental issues now being explored by today’s generation of stem cell researchers, including the field’s potential for regenerative medicine. Ranging from an assessment of the pluripotency of primordial germ cells and their possible applications in treating testicular cancer, to the recovery of once-mordant fertilization-competent sperm, this volume has it all.
269p ladongphongthanh1008 22-04-2024 4 1 Download
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Ebook "Advances in stem cell research" discusses recent advances in stem cell science, including therapeutic applications. This volume covers such topics as biomanufacturing iPS cells for therapeutic applications, techniques for controlling stem cell fate decisions, as well as current basic research in such areas as germ line stem cells, genomics and proteomics in stem cell research. It is a useful book for biology and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research.
401p ladongphongthanh1008 22-04-2024 4 2 Download
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Ebook "Development and reproduction in humans and animal model species" describes human development including sexual reproduction and stem cell research with the development of model organisms that are accessible to genetic and experimental analysis in readily understandable texts and 315 multi-colored graphics. The introductory account of model organisms selected from the entire animal kingdom presents general principles, which are then outlined in subsequent chapters devoted to, for example, sexual development;...
723p manmanthanhla0201 26-02-2024 6 1 Download
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Ebook "Animal cell technology: Basic & applied aspects" ives the readers a complete review of the present state-of-the-art and will be useful for those working in either academic environments or in the biotechnology and pharmaceutical sectors, particularly cell biologists, biochemists, molecular biologists, immunologists, biochemical engineers and all other disciplines related to animal cell culture.
341p manmanthanhla0201 27-02-2024 4 1 Download
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Ebook "The biology of mammalian spermatogonia" provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area.
385p lucchinguyen 28-12-2023 9 2 Download
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Part 1 book "Insights from animal reproduction" includes content: Cryopreservation of sheep produced embryos – current and future perspectives, assisted reproductive techniques on south american wild mammals, the use of reproductive technologies to produce transgenic goats, major components in limiting litter size, germ cell determinant transmission, segregation, and function in the zebrafish embryo.
145p muasambanhan02 25-12-2023 7 1 Download
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Non-gestational choriocarcinoma (NGC) is a rare subtype of malignant germ cell tumour and there is no consensus on its treatment. The lack of suitable preclinical models for NGC is a challenge in drug discovery research.
12p vileonardodavinci 23-12-2023 4 2 Download
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Germ cell tumors are relatively common in young men. They derive from a non-invasive precursor, called germ cell neoplasia in situ, but the exact pathogenesis is still unknown. Thus, further understanding provides the basis for diagnostics, prognostics and therapy and is therefore paramount.
20p vischultz 20-10-2023 4 1 Download
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Currently there are no established fertility preservation options for pre-pubertal boys facing cancer treatment. Granulocyte-colony stimulating factor (G-CSF) treatment has been proposed to be chemoprotective against spermatogonial cell loss in an alkylating chemotherapy model of busulfan-treated adult mice.
13p vischultz 20-10-2023 4 1 Download
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Two thirds of patients with germ-cell cancer (GCC) present as clinical stage I (CSI). Following orchiectomy, active surveillance (AS) has become their standard management. However, 15–50% of patients eventually relapse with metastatic disease after AS. Relapses need to be detected early in order to achieve cure and avoid overtreatment.
8p vioracle 29-09-2023 5 2 Download
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Transformation of germ cell tumor to an alternate malignancy is rare; and it is believed to be secondary to teratomatous elements of the initial tumor surviving chemotherapy and subsequently proliferating. Here, we describe a patient with transformation of a nonseminomatous germ cell tumor to adenocarcinoma.
3p viintuit 26-09-2023 1 0 Download
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Part 1 book "Cellular and molecular approaches in fish biology" includes content: Technologies and strategies for exsitu conservation of aquatic organisms - The role of cryopreservation in long-term management; molecular approaches on DNA damage evaluation after primordial germ cell cryopreservation in zebrafish; the role of epigenetics in fish biology and reproduction - An insight into the methods applied to aquaculture,... and other contents.
244p oursky04 14-09-2023 5 3 Download
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Mature teratoma is the most common germ cell tumor as it represents 95% of germ cell tumors. Although common in children and young adults, ovarian teratoma can occur at any age. Mature teratomas are composed of mature tissues representing elements derived from more than one embryonic germ layer (ectoderm, mesoderm, and endoderm), with ectodermal derivatives being the usual predominant component; however, the finding of a well-differentiated cerebellum is extremely rare.
6p vigamora 23-05-2023 4 2 Download
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We report a rare case in medical literature of a patient with pineal gland teratoma and uncommon metastases. Usually, metastases of this kind of tumor are located in several organs such as lung and breast, but here we found metastases to the spinal cord and vertebrae.
4p vigamora 23-05-2023 7 2 Download
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Most testicular tumors are germ cell tumors; sex cord stromal tumors are infrequent, accounting for only 3–5% of testicular tumors. Unclassifed sex cord stromal tumors are extremely rare. Generally, 10% of sex cord stromal tumors are malignant. We report a case of malignant unclassified sex cord stromal tumor with retroperitoneal lymph node metastasis at first visit and a corresponding literature review.
6p vigamora 23-05-2023 6 2 Download
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The ability to eliminate a parental genome from a eukaryotic germ cell is a phenomenon observed mostly in hybrid organisms displaying an alternative propagation to sexual reproduction. For most taxa, the underlying cellular pathways and timing of the elimination process is only poorly understood.
9p vinarcissa 21-03-2023 3 1 Download
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Complex genetic factors underlie testicular germ cell tumor (TGCT) development. One experimental approach to dissect the genetics of TGCT predisposition is to use chromosome substitution strains, such as the 129.
12p vinarcissa 21-03-2023 2 1 Download
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Malignant ovarian germ cell tumors (MOGCTs) are rare gynecologic neoplasms. The use of nomograms that are based on various clinical indicators to predict the prognosis of MOGCTs are currently lacking.
11p viangelamerkel 27-07-2022 5 2 Download
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For species survival, the germline must faithfully transmit genetic information to the progeny. Transposable elements (TEs) constitute a significant threat to genome stability due to their mobility. In the metazoan germline, their mobilization is limited by a class of small RNAs called PIWI-interacting RNAs (piRNAs) produced by dedicated genomic loci called piRNA clusters.
14p vigalileogalilei 27-02-2022 13 2 Download