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Gingival fibroblast

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  • Natural components of the plants, animals and mineral sources are used as medicines since ancient time as they have fewer or no side effects, plant products have been widely used in controlling cancer as complementary to synthetic medicine is gaining increased popularity. Present study was carried out with different extract of leaf, stem, root and the whole plant of Sida cordata (burm.f.

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  • Novobiocin is a coumarin antibiotic, which affects also eukaryotic cells inhibiting activity of Heat shock protein 90 (Hsp90). The Hsp90 represents a molecular chaperone critical for stabilization and activation of many proteins, particularly oncoproteins that drive cancer progression.

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  • The deleterious role of cigarette smoke has long been documented in various human diseases including periodontal complications. In this report, we examined this adverse effect of cigarette smoke on human gingival fibroblasts (HGFs) which are critical not only in maintaining gingival tissue architecture but also in mediating immune responses.

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  • In dentistry, silver nanoparticles (AgNPs) have drawn particular attention because of their wide antimicrobial activity spectrum. However, controversial information on AgNPs toxicity limited their use in oral infections.

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  • Important player for the regulation of gingival connective tissue homeostasis is the fibroblast, cell able to synthesize and breakdown the collagen fibers and other proteins from the ground substance. In vitro studies have shown that fibroblasts from human normal gingiva produce collagens type I and type III, while cells derived from gingiva of patients with chronic periodontitis failed to produce detectable amounts of type III collagen (Hammouda et al., 1980; Chavier et al., 1984, as cited in Bartold & Narayanan, 2006)....

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