Global oncology
-
Radiotherapy (RT) is an essential treatment modality against cancer and becoming even more in demand due to the anticipated increase in cancer incidence. Due to the rapid development of RT technologies amid financial challenges, we aimed to assess the available RT facilities and the issues with achieving health equity based on current equipment compared to the previous reports from Iran.
11p vishanshan 27-06-2024 1 1 Download
-
Cervical cancer (CC) ranks as the third most commonly diagnosed cancer and the fourth leading cause of cancer-related deaths among women globally. In Addis Ababa, there is a shortage of available evidence concerning the phenomenon of survival time and its predictors among women diagnosed with CC.
10p vikoch 27-06-2024 1 1 Download
-
The diversity of clinical tumor profiling approaches (small panels to whole exomes with matched or unmatched germline analysis) may engender uncertainty about their benefits and liabilities, particularly in light of reported germline false positives in tumor-only profiling and use of global mutational and/or neoantigen data.
10p vioraclene 31-03-2024 2 2 Download
-
Cancer patients often show no or only modest benefit from a given therapy. This major problem in oncology is generally attributed to the lack of specific predictive biomarkers, yet a global measure of cancer cell activity may support a comprehensive mechanistic understanding of therapy efficacy. We reasoned that network analysis of omic data could help to achieve this goal.
12p vioraclene 31-03-2024 3 1 Download
-
Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues found alterations in patterns of DNA methylation, histone posttranslational modifications, and changes in chromatin accessibility.
12p vibransone 28-03-2024 7 2 Download
-
Gastric cancer (GC), gastroesophageal junction cancer (GEJC), and esophageal adenocarcinoma (EAC), together, are leading causes of cancer deaths worldwide. Patient health-related quality of life (HRQoL) and well-being has become increasingly important alongside traditional oncologic outcomes for both patients and clinicians and may aid treatment decisions.
18p vischultz 20-10-2023 3 1 Download
-
Suboptimal treatment upon progression may affect overall survival (OS) results in oncology randomized controlled trials (RCTs). We aim to assess the proportion of trials reporting post-progression treatment.
10p visharma 20-10-2023 4 2 Download
-
The cancer burden is a global public health concern associated with high morbidities and mortalities. Low and middle-income countries are more affected including South Africa. Limited access to oncology services contributes to the late presentation, late diagnosis, and treatment of cancer.
9p visharma 20-10-2023 6 2 Download
-
Access to childhood cancer medicines is a critical global health challenge. There is a lack of sufficient context-specific data in Ghana on access to essential medicines for treating childhood cancers. Here, we present an analysis of essential cancer medicine availability, pricing, and affordability using the pediatric oncology unit of a tertiary hospital as the reference point.
9p vimahuateng 26-11-2021 6 0 Download
-
To assess malnutrition status in hepatocellular carcinoma (HCC) patients by Patient-Generated Subjective Global Assessment (PG-SGA) score. Subjects and methods: A prospective study on 80 patients hospitalized at Military Hospital 103 from 9/2019 - 7/2020. The PG-SGA was collected within first 48 hours of admission.
7p visamoa2711 12-01-2021 8 2 Download
-
Medication non-adherence is associated with poor health outcomes and increased health care costs. Depending on definitions, reported non-adherence rates in cancer patients ranges between 16 and 100%, which illustrates a serious problem.
8p vimanama2711 30-07-2020 13 1 Download
-
Sugarcanehasbeenprimarilyusedtoproducesugarandmolasses.Itiscropthatisgrownin tropicalandsubtropicalclimatesduetoitshigheragriculturalyields.However,thereareseveral coproductsthatcanbeobtainedinvariousstagesofthehandlingofthecropthatcontributeto theaggregate value to theproduction,which isof importance indevelopingcountries facing increasingpricesofnonrenewablefuelsandcyclicalvariationofsugarprices. Forcanesugar industries inoperationaround theworld, there isasubstantialprocessingof sugarcane.
94p loixinloi 08-05-2013 35 4 Download
-
Mixed layers grew to depths of 2,500 to 4,000 meters, with a rapid period of growth beginning shortly before noon and lasting for several hours. Significant differences between the mixed-layer temperatures in the basin and outside the basin were observed. Data analyses and models provide evidence that the circulations are highly complex and that relatively weak upper-level synoptic systems had an impact on the local and regional thermally driven flows in the area.
16p doipassword 01-02-2013 30 3 Download
-
Oncogenic viruses are the known etiologic agents in 15% – 20% of all human cancers. Their impact on global health is signifi cant. The fi rst recognition that cancer can be caused by a virus dates back to observations of Rous sarcoma virus in chickens almost 100 years ago. However, it was not until the 1970s that the mechanistic basis for retroviral transformation became clearer. That era was marked by the discovery of many viral oncogenes and counterpart cellular proto - oncogenes.
510p hyperion75 18-01-2013 46 7 Download
-
Although the psychosocial oncology literature is strong, substantial limitations and unanswered questions remain. Much of the research has focused on heterogeneous samples of patients who vary widely across disease site (e.g., melanoma vs. breast cancer), stage of progression (e.g., localized vs. metastatic), and phase of illness (e.g., initial diagnosis vs. long-term survival). The challenges patients face vary widely across these dimensions, and therefore, it is crucial for research designs to take this into consideration....
8p taisaokhongthedung 09-01-2013 52 1 Download
-
These admittedly rather vague suggestions for man- aging cancer are clearly something of a long shot, but the 12 new Physical Science-Oncology Centers are just starting up (figure 4), and over the coming years they will work together to compare ideas and results from their experimental and theoretical investiga- tions. The success of the initiative will depend on how well the scientists involved can form links between traditional disciplines.
15p taisaokhongthedung 09-01-2013 52 2 Download
-
They have also become important international investors and trade partners, and play a crucial role in world energy markets. Indeed, GCC countries are major exporters of oil in global energy markets, so their stock markets may be susceptible to changes in oil prices. However, the transmission mechanisms of oil price shocks to stock returns in GCC markets should be different from those in net oil-importing countries.
19p quaivattim 04-12-2012 64 3 Download
-
This paper gives an overview of the global insurance market and emerging trends; the importance of the insurance sector for economic development; the significance and elements of an effective regulatory framework; development issues arising from insurance services liberalization; the importance of insurance as a public good; and the implications of GATS negotiations for the insurance sector and areas of potential export interest for developing countries.
74p thangbienthai 27-11-2012 71 8 Download
-
Asthma is a major urban disease and a substantial burden from the standpoint of both the quality of life for the many suffering from the disease and the economics of health care. The global increase in the prevalence of asthma in the last half of the 20th century has affected urban communities in many countries disproportionately. Asthma is an allergic disease for more than 50% of adults and 80% of children. The evidence for a relations- hip between allergic asthma and domestic exposure to cockroaches, mice and dust mites is strong.
72p quygia123 02-11-2012 43 1 Download
-
Until recently, the planet was a large world in which human activities and their effects were neatly compartmentalized within nations, within sectors (energy, agriculture, trade), and within broad areas of concern (environment, economics, social). These compartments have begun to dissolve. This applies in particular to the various global 'crises' that have seized public concern, particularly over the past decade. These are not separate crises: an environmental crisis, a development crisis, an energy crisis. They are all one....
33p yeurauxanh88 28-09-2012 48 4 Download