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Glutathione peroxidase 4
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Glutathione Peroxidase 4 (GPX4) is a key protein that inhibits ferroptosis. However, its biological regulation and mechanism in endometrial cancer (EC) have not been reported in detail.
14p
vialfrednobel
23-12-2023
4
4
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This study aimed to evaluate the potential of exosomes from cancer cells to predict chemoresistance in pancreatic cancer (PC) and explore the molecular mechanisms through RNA-sequencing and mass spectrometry. We sought to understand the connection between the exosomal Medium-chain acyl-CoA dehydrogenase (ACADM) level and the reaction to gemcitabine in vivo and in patients with PC.
14p
vioracle
29-09-2023
5
2
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The purpose of the study is to investigate the function of TRPV4 on ferroptosis in ALI mice induced by lipopolysaccharide (LPS). In vitro, the regulation of TRPV4 on Ca2+ and ferroptosis was detected by CCK-8, fluorescent probe, and western blot in BEAS-2B cells. In vivo, the role of TRPV4 antagonists on ALI mice was analyzed by determination of pulmonary inflammation, pulmonary edema, and ferroptosis.
10p
lyhuyenthu
31-01-2023
6
2
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Ferulic acid (FA; 3-methoxy-4-hydroxycinnamic acid) can eliminate stress-induced damage because of its ability to induce antioxidant activity under stress. The aim of this study was to identify the effects of FA on water status, antioxidant system, and lipid peroxidation in wheat (Triticum aestivum L.) roots exposed to boron (B) stress. Plants were grown in hydroponic culture containing the combination or alone form of 25–75 μM FA and 4–8 mM B. Stress significantly decreased growth (RGR), water content (RWC), proline content (Pro), and osmotic potential (YP).
15p
tudichquannguyet
29-11-2021
8
1
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The aim of the present study was to determine the effect of high temperature stress (HT) and to evaluate the protective role of fungicide pretreatment against HT stress in tomato leaves. The oxidative stress was triggered under HT stress through an increase in the content of malondialdehyde (MDA) and hydrogen peroxide (H2O2). Also, it caused a decline in photosynthetic pigments and enhanced the proline in tomato. However, the activities of catalase (CAT; EC 1.11.1.6), peroxidase (POX; EC 1.11.1.7), and glutathione S-transferase (GST; EC.2.5.1.
14p
tudichquannguyet
29-11-2021
6
1
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Gastric cancer (GC) is a common malignant cancer with a poor prognosis. Ferroptosis has been shown to play crucial roles in GC development. Long non-coding RNAs (lncRNAs) is also associated with tumor progression in GC. This study aimed to screen the prognostic ferroptosis-related lncRNAs and to construct a prognostic risk model for GC.
12p
vimahuateng
26-11-2021
10
2
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Thí nghiệm được thực hiện trên 16 con bò đực giống Brahman (4-5 năm tuổi, khối lượng cơ thể trung bình 877,8 ± 24,15 kg) được chia thành 4 lô để nghiên cứu ảnh hưởng của mức bổ sung kẽm và selen đến chất lượng tinh dịch. Các bò đực giống được chia làm 4 nhóm trong khẩu phần ăn có hàm lượng Zn và Se với 4 mức: 100% NRC (Mức I), 105% NRC (Mức II), 110% NRC (Mức III) và không bổ sung (đối chứng).
8p
vigeorgia2711
03-12-2020
23
2
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Changes in antioxidative enzymes of young and mature leaves of tomato seedlings under drought stress
The effects of exogenous abscisic acid (ABA) on antioxidant enzymes of young and mature leaves of 4-week old Lycopersicon esculentum cv. Ailsa Craig and ABA-deficient mutant, notabilis, were investigated under drought stress. Although ABA induced increases in ascorbate peroxidase (APX), glutathione reductase (GR) and catalase (CAT) activities in drought-stressed young leaves of notabilis, CAT activities remained unchanged in both ABA-treated young and mature leaves of Ailsa Craig under drought.
6p
vitamix
15-02-2019
24
0
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Ultraviolet B (UV-B) irradiation has an adverse effect on plant cells because it causes the generation of reactive oxygen species (ROS). This is scavenged by some endogenous defense systems. In this study, the activities of H2O2- detoxifying antioxidant enzymes in 4 barley cultivars pretreated with high temperature or NaCl before UV-B irradiation were investigated.
10p
vivant2711
01-02-2019
19
0
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The enzymatic activities of purified horseradish peroxidase, selenium-depen-dent glutathione peroxidase, thyroid peroxidase and myeloperoxidase, but not that of lactoperoxidase, were markedly enhanced when added into a reaction mixture containing 5lmnative seminal vesicle protein 4, a major protein secreted from rat seminal vesicle epithelium.
14p
galaxyss3
07-03-2013
48
2
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Một lợi tiểu bắt buộc phải được bắt đầu để khuyến khích sự bài tiết thận. Xơ hoá phổi nghiêm trọng hơn khi thở oxy nồng độ cao, nếu oxy được yêu cầu thấp nhất tập trung có thể được chấp nhận một PaO2 thấp. Liposomal superoxide dismutase và glutathione peroxidase đã được sử dụng lý thực nghiệm.
26p
taoxanh5
07-11-2011
73
3
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