Gold Nano particles

Biofilm is a large collection of colonies containing sessile bacteria which are adhered onto the surface and embedded in the self produced biopolymers such as Extracellular Polymeric Substances (EPS). The surface may be present either in soil or aquatic system as well as in any medical devices or living tissue. These polymeric substances form a cohesive network that interconnects and immobilizes the biofilm cells helping them in mechanical stability.

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The size, shape, and surface morphology of NP‟s play an important role in dominant their physical, chemical, optical, and electronic properties. The NP‟s that attract the eye of most researchers are made from bulk silver and gold (Gade et al., 2008). Nanoparticles can be engineered for shape, chemical nature, size, surface properties, surface modification to transmit special functionalities such as improved strength, catalytic properties and enhanced electrical and thermal conductivity. Different features of the engineered nanoparticles were shown in figure 1.

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Gold nanoparticles (GNPs) an emerging part of nanomedicine holds great promise for revolutionizing medical treatments and therapies in areas such as imaging, drug delivery, faster diagnosis, and tissue regeneration, as well as the development of new medical products. But their safety assessment is a major concern. As body system reacts in a different way than isolated cell line than artificial environment, so in the present experiment pathomorphological assessment ofsub-acute dermal toxicity of green synthesized GNPs and coating with Morinda citrifolia fruit extract (McFE) was undertaken.

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Nano, a word derived from the Greek wordνανoς(nanos, which translated denotes “dwarf”), is nowadays a synonym for a whole research area—the nanosciences. One area within this huge research field is nano-optics, where the response of a nanoparticle to an incoming light wave is investigated. In detail, nanoparticles made of noble metals evoke a special interest, since these particles show a strong response to the incoming light wave. This attribute can be explained by the effect that the mentioned light wave excites the electrons in the conduction band to a collective oscillation.

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