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Grifola Frondosa
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An unusual heteropolysaccharide was isolated from the fruiting bodies of the medicinal mushroom Grifola frondosa, via successive cold aqueous extraction, followed by fractionation through freeze-thawing, precipitation with Fehling solution and dialysis using a membrane with a size exclusion cut-off of 500 kDa.
8p
vihermione
06-01-2023
12
2
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Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models.
10p
vinasaki2711
12-11-2019
13
1
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Basidiomycetes constitute a natural source of biologically active metabolites. Many basidiomycetes have been classified by the National Cancer Institute of the United States as antitumor agents exhibiting an immunomodulatory activity.1 The therapeutic activity is mainly related to polysaccharides or protein-bound polysaccharides, such as glucans, heterogalactans, and glucanproteins, which are present either in the mycelium or in the fruit body.2–6 Among these polysaccharides are b-D-glucans, which are of particular interest because of their pharmacological properties.
6p
the_eye_1991
18-09-2012
67
5
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