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Growth and survival
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The clinical value and impact in patients with EGFR mutation on survival outcomes is further needed to be elucidated to decide whether the application of EGFR-TKIs was appropriate in early lung adenocarcinoma (LUAD) stage appearing as subsolid nodules.
9p
vishanshan
27-06-2024
3
1
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Predicting short-term efficacy and intracranial progression-free survival (iPFS) in epidermal growth factor receptor gene mutated (EGFR-mutated) lung adenocarcinoma patients with brain metastases who receive third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy was of great significance for individualized treatment.
15p
vishanshan
27-06-2024
1
1
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Both first and second-generation EGFR-TKIs are recommended in advanced NSCLC with common EGFR mutations. However, there are few data on the difference in efficacy of EGFR-TKIs based on the type of EGFR mutation and agents.
10p
vishanshan
27-06-2024
1
1
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Mitochondria, which serve as the fundamental organelle for cellular energy and metabolism, are closely linked to the growth and survival of cancer cells. This study aims to identify and assess Siderofexin1 (SFXN1), an unprecedented mitochondrial gene, as a potential prognostic biomarker for lung adenocarcinoma (LUAD).
20p
vishanshan
27-06-2024
2
1
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The partitioned survival model (PSM) and the state transition model (STM) are widely used in costeffectiveness analyses of anticancer drugs. Using different modeling approaches with or without consideration of brain metastasis, we compared the quality-adjusted life-year (QALY) estimates of Osimertinib and pemetrexedplatinum in advanced non-small cell lung cancer with epidermal growth factor receptor mutations.
11p
vikoch
27-06-2024
1
1
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The benefit of adding Zolbetuximab to the treatment in patients with Claudin-18 isoform 2 (CLDN18.2)- positive, human epidermal growth factor receptor 2-negative, locally advanced unresectable or metastatic gastric or gastro-oesophageal junction adenocarcinoma (GC/GEJ) is not yet fully elucidated.
11p
vikoch
27-06-2024
1
1
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A study on the effect of different densities and feed when rearing phyllosoma larvae of slipper lobster (Thenus Orientalis) was conducted at Nha Trang Marine Research and Development Center, Institute of Aquaculture Research No. 3 from January to April 2020 to evaluate the effect of density and types of food on survival, growth (phase transition rate, phyllosoma larval size: CL and CW).
12p
dianmotminh02
03-05-2024
1
1
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The Sarcophyton sp., are very strong and dominant in many coral reef areas. Sarcophyton species are characterized by a distinct sterile stalk, a broad, flared, smooth, mushroomshaped top, with a wide distribution and dominance in numerous coral reef areas extending from the Red Sea and eastern Africa to the western Pacific Ocean.
9p
dianmotminh02
03-05-2024
5
2
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Ebook "VEGF in development" is devoted to vascular endothelial growth factor A (VEGF or VEGFA), a secreted signalling protein of great significance for development and disease in vertebrates. VEGFA controls the proliferation, migration, specialisation and survival of vascular endothelial cells, and it is therefore essential for the establishment of a functional blood vessel circuit.
116p
tracanhphuonghoa1007
22-04-2024
4
2
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This study was conducted to assess the effects of stocking densities on the water quality, survival and growth of the freshwater prawn Macrobrachium rosenbergii postlarvae (PL) cultured in a biofloc system integrated with red seaweed (Gracilaria tenuistipitata).
7p
viellison
28-03-2024
1
1
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Ebook "Physiological mechanisms and adaptation strategies in plants under changing environment: Volume 1" discuss drought and temperature stresses and their mitigation through different means. This volume illuminates how plants that are bombarded by diverse and changing environmental stimuli, undergo appropriate physiological alterations that enable their survival. The information covered in the book is also useful in building apposite strategies to counter abiotic and biotic stresses in plants.
386p
manmanthanhla0201
26-02-2024
5
1
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Part 1 book "Food microbiology" includes content: The scope of food microbiology, micro organisms and food materials, factors affecting the growth and survival of micro organisms in foods, the microbiology of food preservation, microbiology of primary food commodities, food microbiology and public health, bacterial agents of foodborne illness, non bacterial agents of foodborne illness.
284p
muasambanhan08
23-02-2024
3
1
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Pure tubular breast carcinoma is a rare and well-differentiated tumor with high survival and low local recurrence rate. Our study aims to determine the clinical, radiological, appropriate management, and prognosis of this carcinoma.
5p
vitiki
30-01-2024
6
2
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Ebook "Energy return on investment: A unifying principle for biology, economics, and sustainability" presents the reader with a powerful framework for understanding the critical role of the energy return on investment (EROI) in the survival and well-being of individuals, ecosystems, businesses, economies and nations. Growth and development are fundamental and ubiquitous processes at all scales, from individuals to food crops to national economies.
177p
lucchinguyen
28-12-2023
4
2
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Although immune-checkpoint inhibitors (ICI) are overall promissory for cancer treatment, they entail, in some cases, an undesired side-effect called hyperprogressive-cancer disease (HPD) associated with acceleration of tumor growth and shortened survival.
17p
vimichaelfaraday
28-12-2023
4
3
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In clinical trials, poly (ADP-ribose) polymerase inhibitors (PARPi) versus chemotherapy resulted in significantly improved progression-free survival, manageable adverse event profiles, and favorable patient-reported outcomes (PROs) in patients with human epidermal growth factor receptor 2–negative (HER2−) advanced breast cancer (ABC) and germline BRCA1/2 mutations (gBRCA1/2mut).
10p
vileonardodavinci
23-12-2023
3
2
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Dysregulation of inhibitor of differentiation/DNA binding (ID) genes is linked to cancer growth, angiogenesis, invasiveness, metastasis and patient survival. Nevertheless, few investigations have systematically determined the expression and prognostic value of ID genes in acute myeloid leukemia (AML).
12p
vileonardodavinci
23-12-2023
2
2
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Epidermal growth factor receptor (EGFR) amplifcation refers to the copy number increase of EGFR gene, and is often identified as a “bypass” way of Epidermal growth factor receptor Tyrosine kinase inhibitors (EGFRTKI) resistance. We aimed to explore the effect of EGFR amplification on EGFR mutation treatment-naive advanced non-squamous non-small cell lung cancer (NSCLC) patients.
10p
vileonardodavinci
23-12-2023
3
2
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Colorectal cancer (CRC) is the third most common cancer worldwide. However, limited effective biomarkers are associated with the tumorigenesis and prognosis of CRC. Methods: The present study identified potential signatures from The Cancer Genome Atlas (TCGA) database and further validated the identified biomarkers in CRC tissues by immunohistochemistry (IHC).
11p
vialfrednobel
23-12-2023
5
4
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This study aimed to explore the efficiency and safety of the new generation antibody-drug conjugate Trastuzumab deruxtecan (DS-8201a) in treating HER2-positive solid cancers. By searching PubMed, Medline and Ovid for all clinical trials related to the safety and efficacy of DS-8201a. Event rates were calculated for all adverse events (AEs) to evaluate the safety of DS-8201a. Objective response rate (ORR) and progression-free survival (PFS) were summarized to assess the potency of DS-8201a.
9p
vialfrednobel
23-12-2023
5
3
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