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Growth restriction
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The efficacy of checkpoint blockade immunotherapies in colorectal cancer is currently restricted to a minority of patients diagnosed with mismatch repair-deficient tumors having high mutation burden. However, this observation does not exclude the existence of neoantigen-specific T cells in colorectal cancers with low mutation burden and the exploitation of their anti-cancer potential for immunotherapy.
15p
vibransone
28-03-2024
3
2
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Nutritional interventions often fail to prevent growth failure in childhood and adolescent malnutrition and the mechanisms remain unclear. Recent studies revealed altered microbiota in malnourished children and anorexia nervosa.
12p
vioraclene
31-03-2024
3
2
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We experienced two cases with hyper-coiled cord in which fetal-umbilical-placental circulation was improved after amnioinfusion or bed rest. Therefore, amnioinfusion and bed rest to reduce the compression of the vulnerable umbilical cord in cases of hyper-coiled cord might improve the pathologic fetal-umbilical-placental circulation.
4p
viintuit
26-09-2023
0
0
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This article explores a strategic approach to fabricating nano scale silver (100e2000 ppm) doped zinc oxide (ZnOS) in a unique Surfactant-Polyol-Assembly (SPA) that acts as a caging agent, restricting the growth of particles.
14p
viberbers
09-08-2023
6
3
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In this paper, using the asymptotic a priori estimate method, we prove the existence of pullback attractors for a nonautonomous semilinear strongly degenerate parabolic equation, without restriction on the growth order of the polynomial type non-linearity and with a suitable exponential growth of the external force. The obtained results improve some recent ones for the non-autonomous reaction–diffusion equations.
9p
nhanchienthien
25-07-2023
4
3
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5p deletion syndrome is known as cri-du-chat syndrome, but there are no reports on congenital diaphragmatic hernia complications associated with it. A 28-year-old primigravida Japanese woman was referred for 5 mm of nuchal translucency. Fetal growth restriction was found at 20 weeks, and a left-sided congenital diaphragmatic hernia was diagnosed at 24 weeks.
4p
vigamora
23-05-2023
4
2
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Continued part 1, part 2 of ebook "Gabbe’s obstetrics essentials: Normal and problem pregnancies" provide readers with content about: postpartum care; postpartum care and long-term health consideration; lactation and breastfeeding; complicated pregnancy; surgery during pregnancy; trauma and related surgery in pregnancy; trauma and related surgery in pregnancy; cervical insufficiency; preterm labor and birth; premature rupture of the membranes; intrauterine growth restriction;... Please refer to the ebook for details!
573p
tieuduongchi
24-10-2022
10
7
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Lactic acid produced by tumors has been shown to overcome immune surveillance, by suppressing the activation and function of T cells in the tumor microenvironment. The strategies employed to impair tumor cell glycolysis could improve immunosurveillance and tumor growth regulation. Dichloroacetate (DCA) limits the tumorderived lactic acid by altering the cancer cell metabolism.
12p
vielonmusk
21-01-2022
6
0
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The Anatolian water buffalo is a native water buffalo breed only being reared in Turkey. The objective of this study was to investigate gene polymorphisms on exons 4 and 5 of the growth hormone (GH) and on exon 10 of the growth hormone receptor (GHR), which are thought to be related to meat yields of Anatolian water buffalo. Blood samples of 192 water buffaloes from Sivas Province were used in DNA extractions by phenol-chloroform method. DNA samples were amplified by using specific primers in PCR.
6p
dolomite36
30-12-2021
9
0
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Molecular targeted therapy for non-small cell lung carcinoma (NSCLC) is restricted due to resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). This study evaluated the efects of dual targeting of MEK and PI3K in human EGFR-TKI resistant NSCLC cell lines.
12p
vimackenziebezos
29-11-2021
4
1
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The black yeast Hortaea werneckii (Dothideomycetes, Ascomycota) is one of the most extremely halotolerant fungi, capable of growth at NaCl concentrations close to saturation. Although dothideomycetous fungi are typically haploid, the reference H. werneckii strain has a diploid genome consisting of two subgenomes with a high level of heterozygosity.
12p
vibeauty
23-10-2021
12
1
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Assisted reproductive technologies (ART) are widely used to treat fertility issues in humans and for the production of embryos in mammalian livestock. The use of these techniques, however, is not without consequence as they are often associated with inauspicious pre- and postnatal outcomes including premature birth, intrauterine growth restriction and increased incidence of epigenetic disorders in human and large offspring syndrome in cattle.
15p
vibeauty
23-10-2021
11
1
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Gestational disorders such as intrauterine growth restriction (IUGR) and pre-eclampsia (PE) are main causes of poor perinatal outcomes worldwide. Both diseases are related with impaired materno-fetal nutrient transfer, but the crucial transport mechanisms underlying IUGR and PE are not fully elucidated. In this study, we aimed to identify membrane transporters highly associated with transplacental nutrient deficiencies in IUGR/PE.
17p
vibeauty
23-10-2021
4
0
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The molecular basis of compensatory growth in monogastric animals has not yet been fully explored. Herewith, in this study we aim to determine changes in the pig skeletal muscle transcriptome profile during compensatory growth following a feed restriction period.
12p
vitzuyu2711
29-09-2021
12
1
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Incilaria (= Meghimatium) fruhstorferi is an air-breathing land slug found in restricted habitats of Japan, Taiwan and selected provinces of South Korea (Jeju, Chuncheon, Busan, and Deokjeokdo). The species is on a decline due to depletion of forest cover, predation by natural enemies, and collection.
26p
visilicon2711
20-08-2021
10
1
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Intrauterine growth restriction (IUGR) remains a major problem associated with swine production. Thus, understanding the physiological changes of postnatal IUGR piglets would aid in improving growth performance.
16p
vijeeni2711
30-06-2021
6
1
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Rose (Rosa chinensis) is a traditional famous flower with valuable ornamental characteristics. However, drought stress restricts its growth and development, leading to an abnormal phenotype. One of the main transcription factor (TF) protein groups in the plant kingdom are the APETALA2/ethylene-responsive factor (AP2/ ERF) proteins and are potentially involved in the growth and stress responses of various plants.
20p
vilichoo2711
25-06-2021
14
1
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As important forest tree species, biological stress and soil salinization are important factors that restrict the growth of Populus × euramericana. WRKYs are important transcription factors in plants that can regulate plant responses to biotic and abiotic stresses.
13p
vijichea2711
28-05-2021
17
1
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Soil salinity is one of the major abiotic stress factors that affect crop growth and yield, which seriously restricts the sustainable development of agriculture. Quinoa is considered as one of the most promising crops in the future for its high nutrition value and strong adaptability to extreme weather and soil conditions.
15p
vijichea2711
28-05-2021
11
1
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Environmental stress is a crucial factor restricting plant growth as well as crop productivity, thus influencing the agricultural sustainability. Biochar addition is proposed as an effective management to improve crop performance.
11p
vijichea2711
28-05-2021
14
1
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