Guideline adherent treatment

The aim of the present study was to explore whether improvements in guideline adherence can be achieved through the implementation of regional treatment pathways. We chose four regions of Germany with high utilisation of CAs for the study. Here we report the results of the concomitant qualitative study.

9p vishanshan 27-06-2024 1 1   Download

Adjuvant endocrine treatment is essential for treating luminal subtypes of breast cancer, which constitute 75% of all breast malignancies. However, the detrimental side effects of treatment make it difficult for many patients to complete the guideline-required treatment.

12p vioracle 29-09-2023 6 3   Download

Cervical cancer is one of the most common cancers and a major cause of morbidity among women globally. Chemoradiation therapy is the preferred standard treatment for women with stage IB to IVA. However, the benefits of this treatment can only be achieved if patients adhere to the treatment guidelines.

9p vioracle 29-09-2023 2 2   Download

This study evaluated the use of guideline-directed medical therapy (GDMT) for heart failure with reduced and mild reduced ejection fraction (HFrEF) in outpatient department in Hanoi Heart Hospitaland its impact on patients’ midterm outcome.

11p vihulk 27-07-2023 3 2   Download

We conducted a Pattern-of-care (POC) study at two premier-most public-funded oncology centers in Morocco to evaluate delays in care continuum and adherence to internationally accepted treatment guidelines of cervical cancer.

11p vikolindagrabar 27-07-2022 9 1   Download

It is unknown whether and to what degree trials submitted to the US FDA to support drug approval adhere to NCCN guideline-recommended care in their baseline and surveillance CNS imaging protocols. Objective: We sought to characterize the frequency with which the trials cited in US FDA drug approvals for first line advanced NSCLC between 2015 and 2020 deviated from NCCN guideline-recommended care for baseline and surveillance CNS imaging.

8p vielonmusk 21-01-2022 11 0   Download

Evidence from several studies show poor guideline adherence to COPD treatment, but no such study has been undertaken in Norway. The objectives of this study, was to estimate and compare the guideline adherence to COPD treatment in general population-based and hospital-recruited COPD patients, and find possible predictors of guideline adherence.

9p vimontana2711 05-04-2021 11 1   Download

Severe asthma is a complex heterogeneous disease typically requiring advanced therapies. Underlying the treatment of all asthma, however, is the consistent recommendation across international guidelines to ensure that adherence to therapy is adequate. Currently, there is no consensus on an objective marker of adherence.

8p vimichigan2711 26-03-2021 12 1   Download

Despite recognition of asthma as a growing global issue and development of global guidelines, asthma treatment practices vary between countries. Several studies have reported patients’ perspectives on asthma control. This study presents physicians’ perspectives and strategies for asthma management.

11p vimaine2711 26-03-2021 12 3   Download

Although international guidelines encourage urate lowering therapy (ULT) for people who have more than two attacks of gout, only 30 % of patients are prescribed it and only 40 % of those adhere to the treatment.

8p vioregon2711 22-02-2021 7 2   Download

Triple-negative breast cancer (TNBC) remains a challenging topic for clinical oncologists. This study sought to evaluate TNBC versus other breast cancer subtypes with respect to survival parameters. We evaluated possible differences in survival in TNBC by age and by the extent to which evidence-based treatment guidelines were adhered.

11p vijennie2711 29-09-2020 8 0   Download

Studies on the implementation of Clinical Practice Guidelines (CPG) and particularly its effect on breast cancer (BRC) survival on a population-level are scant. This population-based high resolution study from Germany aims at providing data on the usage of BRC treatment, the extent of adherence to CPG and, as a novelty, survival of BRC patients according to major recommended treatment options.

12p vilisa271 22-09-2020 37 1   Download

The value of adjuvant chemotherapy in colorectal cancer is well studied, and guidelines have been established. Little is known about how treatment guidelines are implemented in the everyday clinical setting.

9p vialabama2711 21-09-2020 12 0   Download

In German breast cancer care, the S1-guidelines of the 1990s were substituted by national S3-guidelines in 2003. The application of guidelines became mandatory for certified breast cancer centers. The aim of the study was to assess guideline adherence according to time intervals and its impact on survival.

11p vimoscow2711 29-08-2020 8 2   Download

In this study, we observe the patterns initial palliative treatment for premenopausal patients with HRpositive/HER2-negative MBC and determine if nonadherence to clinical guidelines are associated with worse clinical outcomes in terms of progression-free survival (PFS) and overall survival (OS) in the South Korean population.

8p viputrajaya2711 22-06-2020 7 1   Download

The decision making process for axillary dissection has changed in recent years for patients with early breast cancer and positive sentinel lymph nodes (LN). The question now arises, what is the optimal surgical treatment for patients with positive axillary LN (pN+).

9p viputrajaya2711 22-06-2020 10 1   Download

Group A streptococcus (GAS) is the most common bacterial etiology of pharyngitis but is difficult to distinguish clinically from viral pharyngitis. There are benefits to early antibacterial treatment of GAS pharyngitis, but administering antibiotics to children with viral pharyngitis is ineffective and costly.

7p vidr2711 19-02-2020 63 1   Download

Pseudomonas aeruginosa are established pathogens predominantly in various nosocomial infections which are often life threatening due to limited therapeutic options. The present study was undertaken to analyze the antibiotic susceptibility pattern in the clinical isolates of Pseudomonas aeruginosa, so as to establish the current therapeutic options available for treatment in this geographical area of North East India. The study was conducted on 150 strains of Pseudomonas aeruginosa isolated from various clinical samples.

8p kequaidan2 11-12-2019 13 0   Download

The study was aimed to assess the uses of antibiotic residues consumed in Khartoum State; Sudan. The problem of the study is the usage of antibiotics to food producing animals for treatment, prophylaxis and as growth promoters results in deposition of their residues in various organs and tissues. These residues after consumption via meat, milk and their products may cause adverse side effect such as toxicity, bacterial resistance, allergic reactions and many different side effect may lead to death.

6p chauchaungayxua1 04-12-2019 26 0   Download

Asthma is one of the most common chronic diseases of childhood, affecting an estimated 7 million children (9.4%) in the United States. Asthma care is complex and dynamic requiring temporal, multi-faceted, and coordinated care. The purpose of the Asthma Treat Smart (ATS) application was to help providers provide evidence-based, guideline-compliant care to patients presenting to the pulmonary clinic for treatment of asthma.

15p kequaidan1 05-11-2019 25 0   Download