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H. pylori infection
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Gastric cancer has the fifth highest incidence among cancers in the world and is the most common cancer in South Korea. Several studies suggested a protective role of retinol in oesophageal, liver, lung, and breast cancer, while this effect was still inconsistent in gastric cancer.
11p
viwalton
02-07-2024
0
0
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This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases.
363p
vimeyers
29-05-2024
2
2
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Accumulating evidence has revealed that the gut microbiota influences the effectiveness of immune checkpoint inhibitors (ICIs) in cancer patients. As a part of the human microbiome, Helicobacter pylori (H. pylori) was reported to be associated with reduced effectiveness of anti-PD1 immunotherapy in patients with non-small-cell lung cancer (NSCLC).
8p
vialfrednobel
23-12-2023
7
3
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This study assesses the prevalence and characteristics of H. pylori infection and precancerous conditions in a group of patients suffering from chronic dyspepsia who were subjected to gastric endoscopy and biopsy mapping.
12p
vimahuateng
26-11-2021
14
2
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Regulatory B cells (Bregs) produce antiinflammatory cytokines and inhibits proinflammatory response. Recently, immunosuppressive roles of Bregs in the effector functions of dendritic cells (DCs) were demonstrated. However, cross talk between Bregs and DCs in Helicobacter infection remains unknown. Here, we showed that direct stimulation of bone marrow-derived DCs (BMDCs) with Helicobacter felis (H.
11p
thiencuuchu
27-11-2021
8
2
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In this study, the activity against H. pylori of different solvent extracts and fractionsfrom L. hyssopifolia was evaluated and phytochemical investigation of the highest bioactive methanol extract was performed to establish experimental evidence supporting for traditional use of L. hyssopifolia in treatment of H. pylori infection.
6p
nguaconbaynhay11
01-04-2021
18
1
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Helicobacter pylori (H. pylori) infection causes chronic gastritis, peptic ulcer, gastric cancer and MALT-lymphoma. The association between genotypes of H. pylori and gastric cancer remains controversial. The aim of this study was: To investigate the H. pylori vacA alleles, iceA and cagA in patients with gastric cancer.
8p
viminnesota2711
22-03-2021
11
1
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Recently, an increasing number of studies have focused on the extra-gastrointestinal effects of Helicobacter pylori (H. pylori), including metabolic syndrome, fatty liver, and rheumatic and skin diseases. Osteoporosis is an asymptomatic disease that can eventually lead to fractures and has a significant impact on the quality of life of elderly individuals.
9p
vimariana2711
22-12-2020
19
1
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Gastric Helicobacter pylori (H. pylori) infection and colorectal polyps are more prevalent in African Americans than in the general population. We aimed to investigate whether gastric H. pylori infection is associated with colorectal polyps in African Americans.
7p
virose2711
24-09-2020
11
0
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Although the association between H. pylori and gastric cancer has been well described, the alterations studies are scarce in the humoral immune response in specific anatomical areas of stomach and during the stages of gastric cancer. The aim in this study was to determine the influence of humoral immune responses against H. pylori infection on gastric carcinoma.
7p
vimoscow2711
29-08-2020
5
0
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Chronic Helicobacter pylori infection plays a central role in the development of gastric cancer as shown by biological and epidemiological studies. The H. pylori antibody and serum pepsinogen (PG) tests have been anticipated to predict gastric cancer development.
9p
vimale2711
21-08-2020
12
1
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Gastric cancer is one of the most common and lethal type of cancer worldwide. Infection with Helicobacter pylori (H. pylori) is recognized as the major cause of gastric cancer. However, it remains unclear the mechanism by which Helicobacter infection leads to gastric cancer.
15p
vimale2711
21-08-2020
9
2
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Mannose-binding lectin (MBL) acts in the innate immune response to Helicobacter pylori. Interleukin 8 (IL-8) is a potent cytokine produced by gastric epithelial cells in response to H. pylori.
11p
vidhaka2711
31-07-2020
7
1
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Gastric cancer is the fifth most common cancer worldwide. Along with environmental factors, such as Helicobacter pylori (H. pylori) infection, genetic changes play important roles in gastric tumor formations. miR-584 is a less well-characterized microRNA (miRNA), with apparent activity in human cancers. However, miR-584 expression pattern in gastric cancer development has remained unclear.
12p
vidhaka2711
31-07-2020
13
1
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H. pylori colonize all human populations worldwide. The risk of being colonized by H. pylori depends on geographic area, socioeconomic status and age, and initial colonization is thought to occur during early childhood. In developing countries the infection can be almost ubiquitous, whereas in industrialized countries H. pylori infect 30–50% of adults. H pylori response to both Clarithromycin and Metronidazole antibiotic sensitivity was giving the same figures. In respect to gender, 90.9 % of males and 88.2 % of females were sensitive to both antibiotics.
13p
angicungduoc6
20-07-2020
9
2
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Helicobacter pylori infection is recognized as the main risk factor for gastric cancer (GC), the fifth most common neoplasia worldwide. H. pylori interacts with the immune system, disrupting the cytokine network and inducing chronic inflammation.
8p
vikuala271
13-06-2020
11
1
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Helicobacter pylori (H. pylori) is thought to have an oncogenic effect on the development of gastric malignancies. However, the effect of H. pylori status on the prognosis of gastric diffuse large B-cell lymphoma (DLBCL) remains unconfirmed.
10p
vikuala271
13-06-2020
6
1
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Globally, Helicobacter pylori (H. pylori) is becoming an increasingly troublesome economic and public health problem. Over 50% of the world’s population was estimated to harbor H. pylori in the upper gastrointestinal tract (GIT) and over 80% of them reside in developing nations. Unless treated, colonization persists lifelong where H. pylori presents a key factor in the etiology of GIT diseases; ranging from asymptomatic chronic gastritis up to gastric carcinoma. Therefore, accurate and timely diagnosis is the first step to address this burdensome problem.
20p
chauchaungayxua5
08-05-2020
11
1
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Helicobacter pylori neutrophil-activating protein (HP-NAP) is involved in H. pylori-induced gastric inflammation. Due to its immunogenic and immunomodulatory properties, HP-NAP has been used for developing vaccines against H. pylori infection and new drugs for cancer therapy.
11p
viuchiha2711
21-04-2020
5
0
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Helicobacter pylori induces chronic inflammation of the underlying gastric mucosa causing gastritis and other complications. H. pylori infection once acquired is believed to persist lifelong unless treated. This is a cross-sectional epidemiological study to find the prevalence of the infection in asymptomatic healthy blood donors attending the SVMCHRC blood bank, Puducherry.
6p
cothumenhmong4
25-03-2020
12
1
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