Halogenated organic derivatives

A series of novel halogenated 3-hydroxyflavones (3HFs) were prepared by reacting halogenated hydroxyacetophenones with the appropriate aromatic aldehyde. Glycosylation of 3HFs with acetobromoglucose and deprotection of the acetyl protective groups afforded the desired 3-O-flavonoids glycosides in satisfactory yields. All the prepared compounds were tested for their cytotoxic activity against HCT-116, MCF-7, and OVCAR-3 human cancer cell lines. The 3HFs exhibited higher cytotoxic activities compared with the glycosylated flavonoids.

11p tudichquannguyet 29-11-2021 12 1   Download

Chapter 22 - What does the benzene ring do to its substituents? After attending lectures, reading the text and working assigned problems related to this chapter, students will have acquired the following knowledge and abilities: Given the IUPAC name of a phenol derivative, be able to draw its structure; know how resonance influences the stability of benzylic cations, anions, and radicals as compared to similar non-benzylic species; be able to apply a benzyl ether as a protecting group in multi-step synthesis; given a series of phenols, be able to rank their relative acidity.

38p larachdumlanat122 26-11-2020 8 0   Download

This publication contains the competition problems (Volume 2) from the 21-40, international Chemistry Olympiads (ICHO) organized in the years 1989-2008 and is a continuation of the publication that appeared last year as Volume 1 andcontained competition problems from the first twenty ICHOs.The whole review of the competition tasks set in the ICHO in its fourty-year history is a contribution of the ICHO International.

136p vuongtuyetsuong 09-04-2017 111 8   Download

The modern organic movement began in Europe around the 1920s, when a group of farmers and consumers sought an alternative to the industrialisation of agriculture. Of key importance to these farmers and consumers was caring for the soil and natural processes upon which agriculture depends, including not using inputs such as artificial fertilisers and synthetic chemicals. A leading figure at the time was the Austrian thinker, Rudolf Steiner, whose ideas led to a system of cultivation known as biodynamic.

6p cao_can 02-01-2013 61 3   Download