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Healthy immune system plays
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Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses
The interleukin (IL)-1 pathway is primarily associated with innate immunological defense and plays a major role in the induction and regulation of inflammation. Both common and rare genetic variation in this pathway underlies various inflammation-mediated diseases, but the role of rare variants relative to common variants in immune response variability in healthy individuals remains unclear.
17p
vibransone
28-03-2024
3
2
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Blood plasma proteins play an important role in immune defense against pathogens, including cytokine signaling, the complement system, and the acute-phase response. Recent large-scale studies have reported genetic (i.e., protein quantitative trait loci, pQTLs) and non-genetic factors, such as age and sex, as major determinants to inter-individual variability in immune response variation.
15p
viellison
28-03-2024
3
2
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A healthy immune system plays a particularly important role in newborns, including in calves that are far more susceptible to infections (viral, bacterial and other) than adult individuals. Therefore, the present study aimed to evaluate the influence of HMB on the chemotactic activity (MIGRATEST® kit), phagocytic activity (PHAGOTEST® kit) and oxidative burst (BURSTTEST® kit) of monocytes and granulocytes in the peripheral blood of calves by flow cytometry.
12p
vigandhi
23-02-2022
13
1
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Besides, Expanded Programme on Immunization (EPI) and fertility regulation activities, Integrated management of Childhood Illnesses (IMCI) is also playing an important role in child survival through reducing child mortality and morbidity and promoting child growth, development and healthy practices. Effective implementation of IMCI case management guidelines improved quality of care in health facilities across various settings in Bangladesh. Considering its impact at a low cost, government plans gradual expansion of IMCI programme in the country.
84p
nhamnhiqa
01-03-2013
60
1
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