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Hemophagocytic lymphohistiocytosis
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Haemophagocytic lymphohistiocytosis (HLH) is an uncommon systemic inflammatory syndrome that can happen secondary to numerous conditions. It rarely occurs due to dengue infection causing significant mortality and morbidity even with appropriate treatment.
6p
vitiki
30-01-2024
3
2
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Wolman disease is a rare disease caused by the absence of functional liposomal acid lipase due to mutations in LIPA gene. It presents with organomegaly, malabsorption, and adrenal calcifications. The presentations can resemble hemophagocytic lymphohistiocytosis, the life threatening hyperinfammatory disorder.
9p
vitiki
30-01-2024
3
2
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Hội chứng thực bào máu (Hemophagocytic lymphohistiocytosis - HLH) là một hội chứng lâm sàng hiếm gặp và thường gây tử vong, đặc trưng bởi tình trạng đáp ứng viêm quá mức do hoạt hóa bất thường đại thực bào và tế bào lympho T gây độc tế bào, dẫn đến cơn bão cytokine và tổn thương các cơ quan.
6p
vispacex
13-11-2023
7
3
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Hemophagocytic lymphohistiocytosis (HLH) is a systemic inflammation disorder secondary to immune dysregulation. Patients may present with fevers, splenomegaly, bone marrow failure and hemophagocytosis, among other clinical and laboratory findings.
6p
viintuit
26-09-2023
2
0
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Monocyte plays a crucial role in phagocytosis. This case report describes a 50-year-old female patient with septicemia who manifested leucocytosis with neutrophilia and severe anemia during her infection course. The peripheral blood examination strikingly showed platelet phagocytosed by the monocytes.
4p
viwarmachine
03-07-2023
3
1
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Adult-onset Still’s disease (AOSD) is a rare autoinflammatory condition. It is a diagnosis of exclusion by ruling out all related infectious, inflammatory, autoimmune, and malignant diseases. We present a case of a 23-year-old Caucasian male who presented with fever, night sweats, joint pain, weight loss, and diarrhea.
5p
viwhitewolf
03-07-2023
4
2
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Hodgkin lymphoma (HL) is a hematologic malignancy that comprises about 10% of all lymphomas with the most common type being classical HL (cHL). The typical clinical presentation of cHL involves multiple region lymphadenopathy and a chest mass found on imaging.
5p
viwhitewolf
03-07-2023
6
2
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Hội chứng thực bào máu (HLH: Hemophagocytic Lymphohistiocytosis) là một bệnh lý xuất hiện do các đại thực bào hoạt động quá mức dẫn đến hậu quả là các tế bào hồng cầu, bạch cầu, tiểu cầu và các tế bào tiền thân huyết học bị thực bào cho nên bệnh có tên gọi là thực bào máu. Bài viết Hội chứng thực bào máu liên quan với bệnh ác tính ở trẻ em báo cáo 1 trường hợp HLH thứ phát ở bệnh nhi mắc bạch cầu cấp dòng lympho B đang điều trị giai đoạn duy trì.
8p
vinebula
02-06-2023
9
4
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Hemophagocytic lymphohistiocytosis is a life-threatening disease heralded by fever, cytopenia, hepatosplenomegaly, and multisystem organ failure. Its association with genetic mutations, infections, autoimmune disorders, and malignancies is widely reported.
7p
videadpool
05-05-2023
5
2
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Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome that requires prompt diagnosis and appropriate treatment.
8p
vimanama2711
28-07-2020
8
1
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Hemophagocytic lymphohistiocytosis (HLH) is a rare potentially fatal illness characterized by impaired natural killer and cytotoxic T cell function. Chronic granulomatous disease (CGD) is an inherited immune deficiency caused by a defect in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex.
4p
vivalanbo2711
19-03-2020
16
1
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Hemophagocytic lymphohistiocytosis (HLH) is an infrequent but life-threatening disease due to excessive immune activation. Secondary HLH can be triggered by infections, autoimmune diseases, and malignant diseases. Streptococcus pneumoniae is a pathogenic bacterium responsible for invasive pneumococcal disease (IPD) such as meningitis and bacteremia.
6p
vivalanbo2711
19-03-2020
13
1
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Stevens-Johnson syndrome (SJS) is a severe skin and mucosal bullous disease. When complicated with Hemophagocytic lymphohistiocytosis (HLH), the condition is especially life-threatening.
4p
vinatri2711
29-02-2020
11
1
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Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder characterized by prolonged fever, cytopenia, hepatosplenomegaly, rash, icterus, and other neurological symptoms. Successful treatment of HLH by etoposide has improved outcomes for children with HLH.
6p
videshiki2711
21-02-2020
22
1
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Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hematological disorder associated with severe systemic inflammation caused by an uncontrolled and ineffective immune response resulting in cytokine storm.
5p
videshiki2711
21-02-2020
15
1
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The differences between the clinical characteristics and survival time in malignancy- and nonmalignancy–associated secondary hemophagocytic lymphohistiocytosis (HLH) are unclear. Here, we describe the clinical characteristics, prognostic factors, and survival outcomes of malignancy-associated HLH compared to that of non-malignancy–associated HLH.
7p
vivalletta2711
11-01-2020
26
2
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Hemophagocytic Lymphohistiocytosis (HLH) is a rare, complex, life-threatening hyper-inflammatory condition due to over activation of lymphocytes mediated secretory cytokines in the body.
7p
vidublin2711
13-01-2020
10
0
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Hemophagocytosis, a phenomenon of which activated macrophages phagocytosed hematopoietic elements was reportedly observed in severe dengue patients. In the present study, we investigated whether markers of macrophage activation syndrome (MAS) can be used as differential diagnostic markers of severe dengue.
8p
viwashington2711
04-12-2019
9
0
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Hemophagocytic lymphohistiocytosis (HLH) is an uncommon and life-threatening disorder that may rarely complicate the clinical course of Orientia tsutsugamushi disease (scrub typhus). Here, we describe the clinical features, laboratory parameters, management, and outcome of 16 children with scrub typhus-associated HLH. All patients satisfied the HLH-2004 diagnostic criteria. All patients had fever of unknown origin and multisystem damage. Raised hepatic transaminases and abnormalities in routine blood test were observed in all children. Imaging tests showed abnormalities in 10 cases.
6p
trinhthamhodang1
14-11-2019
10
1
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Hội chứng thực bào máu (HCTBM) thể gia đình (familial hemophagocytic lymphohistiocytosis, FLH) ở trẻ sơ sinh rất hiếm được báo cáo vì sự phức tạp trong chẩn đoán và điều trị. Mục tiêu: Tăng cường kiến thức và kinh nghiệm trong chẩn đoán và điều trị hội chứng thực bào máu ở trẻ sơ sinh.
8p
vihani2711
18-09-2019
24
1
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