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Hepatic steatosis
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Immune related adverse events impacting the liver are common from immune checkpoint inhibitor (ICI) therapy; however, there is little data regarding the subclinical impact of ICIs on liver inflammation. The study aims to determine whether ICI therapy effects liver attenuation and liver enzymes in melanoma patients with and without hepatic steatosis.
7p
vialfrednobel
23-12-2023
7
3
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Determine the proportion of NAFLD patients with carotid intima-media thickness (CIMT) ≥ 0.8 mm. Investigation of the correlation between the hepatic steatosis and liver fibrosis by FibroScan - CAP with CIMT in NAFLD patients. Determination of predictive risk factors of CIMT ≥ 0.8 mm in NAFLD patients.
9p
vigeorge
06-12-2023
2
1
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Chronic starvation and refeeding have been associated with liver injury (LI). We present a patient with anorexia nervosa who exhibited both phenomena of malnutrition-related LI. At presentation, aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were elevated at 154 and 136 U/L, respectively, and rose rapidly to peaks of 750 and 638 U/L, respectively, as nutrition was introduced.
4p
viintuit
26-09-2023
4
0
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Duck species are known to have different susceptibility to fatty liver production in response to overfeeding. In order to better describe mechanisms involved in the development of hepatic steatosis and differences between species, transcriptome analyses were conducted on RNAs extracted from the livers of Pekin and Muscovy duck species and of their reciprocal hybrids.
14p
viseulgi2711
31-08-2021
14
1
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Overfeeding reduces laying performance in broiler breeder hens, which is associated with obesity, hepatic steatosis and systemic inflammation. To unravel the underlying mechanisms governing the effect of feeding regimes on energy metabolism and egg production, a transcriptomics approach was carried out for screening differentially expressed genes (DEGs) in ovary, liver and adipose tissues of broiler chickens under ad libitum and restricted feeding.
9p
visilicon2711
20-08-2021
7
1
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Deregulation in lipid metabolism leads to the onset of hepatic steatosis while at subsequent stages of disease development, the induction of inflammation, marks the transition of steatosis to non-alcoholic steatohepatitis.
12p
vilichoo2711
25-06-2021
4
1
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Accurate assessment of liver health prior to undertaking resectional liver surgery or chemoembolisation for primary and secondary cancers is essential for patient safety and optimal outcomes. LiverMultiScan™, an MRI-based technology, non-invasively quantifies hepatic fibroinflammatory disease, steatosis and iron content.
7p
vimanila2711
29-06-2020
5
1
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Serum transaminases provide modest predictive value for hepatic steatosis in youth. The ALT threshold for predicting hepatic steatosis is significantly lower than current clinical thresholds for predicting non-alcoholic fatty liver disease.
8p
vichengna2711
25-02-2020
15
0
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Controlled attenuation parameter (CAP) is a recently introduced, non-invasive and quantitative method to evaluate hepatic steatosis demonstrated in adults, but limited in obesity and not well evaluated in children.
9p
virome2711
13-01-2020
15
1
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Genetic variation near the interferon lambda 3 (IFNL3) is known to be associated with response to pegylated interferon (pegIFN) and ribavirin combination therapy in patients with chronic hepatitis C virus (HCV) infection which is often accompanied by hepatic steatosis.
6p
vicaracas2711
27-11-2019
9
0
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This study aimed to assess the relationship between steatosis and long-term outcomes of patients with chronic hepatitis C (CH) and liver cirrhosis (LC).
8p
vilusaka2711
19-11-2019
15
1
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Chronic hepatitis C virus (HCV) infection is a systemic disease that leads to increased risks of cirrhosis and its complications, as well as extrahepatic disturbances, including immune-related disorders and metabolic alterations such as insulin resistance and steatosis. Recent accumulating evidence suggests that HCV infection can increase cardiovascular risk, and that viral eradication can improve cardiovascular outcomes in the clinical setting. These data are strengthened by evidence identifying potential mechanisms (in)directly linking HCV infection to vascular damage.
8p
kequaidan1
16-11-2019
12
0
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Chinese medicinal formula BNG-1, a non-specific inhibitor of phospho-diesterases (PDEs), can be considered as a potential anti-inflammatory agent. The present study was aimed at determining the effects of BNG-1 on the development of non-alcoholic fatty liver disease (NAFLD) in mice.
9p
vihasaki2711
12-11-2019
14
1
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Nonalcoholic fatty liver disease (NAFLD) has become highly prevalent, paralleling the pandemic of obesity and diabetes, and represents an important burden. Nutrition knowledge is fundamental, in prevention, evolution and treatment of NAFLD.
9p
vihasaki2711
12-11-2019
15
1
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The present study aimed to examine the effects of the types of high-calorie diets (high-fat and high-fathigh-sucrose diets) and two different developmental stages (post-weaning and young adult) on the induction of metabolic syndrome. Male, post-weaning and adult (3- and 8-week old, respectively) Sprague Dawley rats were given control, high-fat (60% kcal), and high-fat-high-sucrose (60% kcal fat + 30% sucrose water) diets for eight weeks (n = 6 to 7 per group). Physical, biochemical, and transcriptional changes as well as liver histology were noted.
10p
trinhthamhodang1
14-11-2019
10
0
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Fructose ingestion is often associated with hepatic steatosis and hypertriglyceridemia. The homeostasis of hepatic lipids is mainly determined by the interplay of lipogenesis and fatty acid β-oxidation. In this study, we hypothesized that high fructose intake disturbs hepatic lipid metabolism through an imbalance between these processes.
8p
nutifooddau
27-01-2019
18
1
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Liver biopsy is a procedure that involves obtaining a small piece of liver tissue, which is then analyzed in the laboratory. Liver biopsy may be used to evaluate a mass seen on images, diagnose unexplained liver diseases or abnormal liver function tests, and to determine the severity of the liver disease including hepatitis, fibrosis, and steatosis. Liver biopsy is an invasive procedure, and its complications are rare but potentially lethal. Therefore, it is necessary to perform liver biopsy safely from clinical aspect and to take specimen steadily from a pathological one....
300p
camchuong_1
10-12-2012
42
7
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This chapter introduces the history, definitional and semantic issues, spectrum and general importance of non-alcoholic fatty liver diseases (NAFLD). Nonalcoholic steatohepatitis (NASH) is a form of metabolic liver disease in which fatty change (steatosis) is associated with lobular inflammation, hepatocyte injury and/or hepatic fibrosis. It comprises a pathogenic link in the chain of NAFLD that extends from bland steatosis to some cases of ‘cryptogenic cirrhosis’.
331p
crazy_sms
07-05-2012
103
12
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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Hepatic steatosis secondary to capecitabine: a case report...
3p
thulanh26
09-12-2011
45
4
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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis...
6p
thulanh9
07-10-2011
39
2
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