Hepatotoxicity in male rats

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Protective effect of aerial parts of Portulaca oleracea and Ficus carica leaves against diclofenac sodium induced hepatotoxicity in rats

The present experiment is aimed to evaluate the hepatoprotective effects of purslane (PuE) and fig leaves (FlE) extracts on diclofenac-sodium (DS) induced hepatotoxicity in rats. Adult male rats were pretreated orally with PuE and FlE extracts at a dose of 10ml/kg and 200mg/kg body weight, respectively for 14 days. Co-treatment of DS 16mg/kg body weight was given orally for 7days.

7p viisac 23-09-2023 2 1 Download

The mitigative effect of Raphanus sativus oil on chromium-induced geno- and hepatotoxicity in male rats

To study the impact of radish oil on the possible genotoxic and hepatotoxic effects of hexavalent chromium, male rats were divided into 4 groups. Group 1 served as control, group 2 received radish oil at the recommended human therapeutic dose (0.07 mL/kg) by gavage, group 3 received sodium dichromate dihydrate (SDD) 520 mg/L in drinking water, and group 4 received both SDD and radish oil as previously mentioned in groups 2 and 3. All treatments were continued for six months.

9p kequaidan1 16-11-2019 12 1 Download