Heteroaromatic aldehydes
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Liquid phase tandem Knoevenagel–Michael condensation of various aromatic and heteroaromatic aldehydes with barbituric acid or 2-thiobarbituric acid and malononitrile was studied in a one-pot three-component reaction. For the first time, TMDP was employed as a safe and efficient solvent and/or catalyst in the liquid and aqueous ethanol medium, respectively, for the practical and eco-friendly Knoevenagel–Michael condensation.
10p tudichquannguyet 29-11-2021 8 1 Download
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In continuation of our work, new diazenyl chalcones scafolds (C-18 to C-27) were efciently synthesized from substituted acetophenone azo dyes (A–E) by base catalyzed Claisen–Schmidt condensation with different substituted aromatic/heteroaromatic aldehydes.
19p vijiraiya2711 27-05-2020 5 1 Download