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High resolution electrospray ionization

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  • Phellinus gilvus (Schwein.) Pat, a species of ‘Sanghuang’, has been well-documented for various medicinal uses, but the genome information and active constituents are largely unknown. Here, we sequenced the whole-genome of P. gilvus, identified phenylpropanoids as its key anti-cancer components, and deduced their biosynthesis pathways. A 41.11-Mb genome sequence was assembled and the heatmap created with high-throughput chromosome conformation capture techniques data suggested all bins could be clearly divided into 11 pseudochromosomes. Cellular experiments showed that P.

    pdf11p covid19 14-06-2020 26 0   Download

  • In this study, systematic separation and subsequent pharmacological activity studies were carried out to identify cytotoxic natural products from the dried stems of Millettia pachyloba Drake. Five previously undescribed isoflavones, pachyvones A–E; one previously undescribed xanthone, pachythone A; and twenty-two known compounds were obtained. The structures of these compounds were assigned on the basis of 1D/2D NMR data and high-resolution electrospray ionization mass spectroscopy analysis.

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  • A phytochemical study of Uvaria boniana Fin. & Gagnep collected at Pumat National Park, Nghe An province led to the isolation of five secondary metabolites, including uvaridacol G (1); 4-methyl-4-[(2Z)-3'-phenylprop-2'-en-1'-yl]cyclohex-2-en-1-one (2).

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