Higher potential
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In silico screening of alkaloids as potential inhibitors of HER2 protein for breast cancer treatment
his study focused on finding alkaloid compounds collected from Chemfaces database that inhibit HER2 enzyme employing computational methods such as molecular docking and ADMET prediction. Out of 118 phytochemicals docked to the ATP binding site of the HER2 kinase domain, 10 alkaloid compounds exhibited higher binding affinity than the reference inhibitor and satisfied the Lipinski’s rule of five. All compounds have good pharmacokinetic properties.
10p dianmotminh02 03-05-2024 4 3 Download
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The main goal of this paper is to briefly describe the educational quality assurance procedures of Jubail Industrial College and share its experience with other local and international institutions that are potentially interested in implementing similar quality assurance procedures in their various departments.
11p viarnault 25-04-2024 3 1 Download
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The world eagerly anticipates advancements in AI technologies, with substantial ongoing research on the potential AI applications in the domain of education. The study aims to analyse publications about the possibilities of artificial intelligence (AI) within higher education, emphasising their bibliometric properties.
17p viarnault 25-04-2024 5 2 Download
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Canna edulis. Ker starch processing wastewater from craft villages contains high organic concentration such as starch, cellulose, xylan, protein… and especially high starch concentration after the states of grinding, sedimentation and filtration. The concentration of COD and BOD5, SS and coliform of wastewater are hundreds times higher than standards.
7p vilarry 01-04-2024 2 1 Download
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Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials. Initial CHMI studies showed significantly higher durable protection against homologous than heterologous strains, suggesting the presence of strain-specific vaccine-induced protection.
17p vibransone 28-03-2024 3 2 Download
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Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental factors during early development and influence future health outcomes.
25p vibransone 28-03-2024 5 1 Download
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In addition to lean, universities have also the responsibility to protect the environment. As a matter of fact, lean and green practices, share the same objective - that is to reduce waste. However, studies on lean and green universities is rather scarce. Even though there are evidences that these two concepts can be integrated, the synergy between the two concepts has yet to be discovered. This paper will elaborate on how lean and green can be integrated and the potential benefits towards sustainable higher education institutions performances.
8p longtimenosee06 27-03-2024 2 1 Download
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Dislocation of the knee is a serious and potentially limb-threatening injury. There are three types of dislocation around the knee joint: patellofemoral, tibiofemoral, and tibiofibular. Tibiofemoral dislocation is the variant that is deemed the most serious, with a higher risk of compromise to the popliteal artery and common peroneal nerve.
7p vilazada 31-01-2024 3 2 Download
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This study aims to investigate the effectiveness of Quizlet in enhancing vocabulary mastery and understanding of lesson content for EMI students at the School of Languages and Tourism, Hanoi University of Industry, as perceived by the students themselves.
5p vimarillynhewson 02-01-2024 6 3 Download
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Part 1 book "Berne and levy physiology" includes content: principles of cell function; homeostasis of body fluids; signal transduction, membrane receptors, second messenger; the nervous system - introduction to cells and systems, generation and conduction of action potentials, synaptic transmission, the somatosensory system, the special senses, organization of motor function, higher functions of the nervous system, the autonomic nervous system and its central control,... and other contents.
462p oursky07 24-10-2023 6 1 Download
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Ebook "Speed maths for kids: Helping children achieve their full potential" makes the methods and principles for maths calculations clearer, encourages creative thought, and is just plain fun. Now fully revised with new chapters and strategies, the book also has notes throughout for parents and teachers to help their children engage and learn more easily.
197p dangsovu 20-10-2023 4 3 Download
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Despite decades of effort to reduce racial cancer disparities, Black people continue to die at higher rates from cancer than any other U.S. racial group. Because prevention is a key to the cost-effective and long-term control of cancer, the potential for cancer genetic counseling to play a central role in reducing racial cancer disparities is high.
14p visharma 20-10-2023 6 2 Download
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The aquaporin (AQP) family of proteins has been implicated in the proliferation and growth of gliomas. Expression of AQP8 is higher in human glioma tissues than in normal brain tissues and is positively correlated with the pathological grade of glioma, suggesting that this protein is also involved in the proliferation and growth of glioma.
14p visharma 20-10-2023 7 2 Download
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Part 1 book "Berne and levy physiology" includes content: Principles of cell function; homeostasis of body fluids; signal transduction, membrane receptors, second messenger; generation and conduction of action potentials; synaptic transmission; the somatosensory system; the special senses; organization of motor function, higher functions of the nervous system, the autonomic nervous system and its central control,... and other contents.
682p oursky04 14-09-2023 7 3 Download
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Nowadays, the utilization of business intelligence (BI) in educational environments can be seen as a potential solution to foster educational data for better planning academic resources and performance. However, at no time in the past have educational institutions and universities faced so many challenges in gathering and integrating huge amounts of educational data from multiple, distributed and heterogeneous sources.
9p vicaptainmarvel 21-04-2023 7 2 Download
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Nowadays, as the global population grows, the demand for food is also becoming higher each day. Together with the rise in food demand, Muscovy duck has been gradually bred industrially as a poultry food supply along with the chicken. The change from traditional to industrial breeding poses a potential risk of pathogenic bacteria infection and antimicrobial resistance bacteria.
17p vicaptainmarvel 21-04-2023 4 2 Download
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Africa is home to numerous cattle breeds whose diversity has been shaped by subtle combinations of human and natural selection. African Sanga cattle are an intermediate type of cattle resulting from interbreeding between Bos taurus and Bos indicus subspecies.
14p vinarcissa 21-03-2023 5 1 Download
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Part 1 of ebook "Quantum field theory II: Introductions to quantum gravity, supersymmetry and string theory" provide readers with content about: introduction to quantum gravity; introduction to supersymmetry; geometrical aspects, structure of spacetime and development of the general theory of relativity; the schwinger-deWitt technique; dimensional regularization of the one loop contribution to quantum general relativity;...
201p damtuyetha 16-02-2023 6 3 Download
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Gene expression is potentially an important heritable quantitative trait that mediates between genetic variation and higher-level complex phenotypes through time and condition-dependent regulatory interactions.
13p vihagrid 30-01-2023 5 3 Download
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Rhizobium tropici, a member ofthe Rhizobiaceae family, has the ability to synthesize and secrete extracellular polysaccharides (EPS). Rhizobial EPS have attracted much attention from the scientific and industrial communities. Rhizobial isolates and R. tropici mutants that produced higher levels of EPS than the wildtype strain SEMIA4080 were used in the present study.
7p vihermione 06-01-2023 7 2 Download