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Highly proliferative
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Glioblastoma (GB) is the most aggressive of all primary brain tumours and due to its highly invasive nature, surgical resection is nearly impossible. Patients typically rely on radiotherapy with concurrent temozolomide (TMZ) treatment and face a median survival of~14 months.
14p
visharma
20-10-2023
8
2
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Mangrove is one of the highly productive ecosystems and contains diverse plants and microbial communities. Bacterial endophytes from mangroves are considered as a prolific source of biological molecules with important functions in the protection of mangrove plants against herbivores, insects as well as pathogens.
11p
vicaptainmarvel
21-04-2023
8
2
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Response guided treatment in breast cancer is highly desirable, but the effectiveness is only estab‑ lished based on residual cellularity from histopathological analysis after surgery. Tubule formation, a key component of grading score, is directly associated with cellularity, with significant implications on prognosis.
12p
vikolindagrabar
27-07-2022
5
1
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Infective endocarditis is a rare but severe condition associated with a high mortality rate in small animal patients. This condition is caused by a microbial (most often bacterial) infection of the valvular portion of the endocardium, from which proliferative and/or erosive lesions on the cardiac valves or immediately adjacent structures develop. The two most commonly affected cardiac valves are the aortic and mitral valves.
6p
vigandhi
23-02-2022
14
1
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How intestinal epithelial cells interact with the microbiota and how this is regulated at the gene expression level are critical questions. Smarcad1 is a conserved chromatin remodeling factor with a poorly understood tissue function. As this factor is highly expressed in the stem and proliferative zones of the intestinal epithelium, we explore its role in this tissue.
20p
viarchimedes
26-01-2022
7
0
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The highly prolific breeds of domestic sheep (Ovis aries) are globally valuable genetic resources for sheep industry. Genetic, nutritional and other environmental factors affect prolificacy traits in sheep. To improve our knowledge of the sheep prolificacy traits, we conducted mRNA-miRNA integrated profiling of ovarian tissues from two pure breeds with large (Finnsheep) vs. small (Texel) litter sizes and their F1 crosses, half of which were fed a flushing diet.
17p
vilarryellison
29-10-2021
5
0
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Small-cell lung cancer (SCLC) is a highly proliferative, rapidly growing tumor with a poor prognosis, even in cases of limited disease (LD). Timely and accurate high-intensity therapy is necessary. For concurrent chemoradiotherapy (CCRT), etoposide/platinum (EP)-based regimens are recommended, although irinotecan/ platinum (IP)-based regimens are also effective with radiotherapy.
9p
vianrose2711
27-04-2021
5
1
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Diffuse pigmented villonodular synovitis (PVNS) of the knee is a rare proliferative joint disease associated with high recurrence rates following surgical treatment. Intra-articular joint instability in conjunction with PVNS implies complex reconstructive strategies due to the destructive nature of the disease.
6p
vitennessee2711
01-02-2021
9
2
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Angiogenesis is a proliferative process resulting in the development of new blood vessels from existing endothelial cells and is considered crucial for tumor growth and metastasis. Tumor angiogenesis can be quantified by microvascular density (MVD), which is evaluated in highly vascularized tumor areas (hot spots) by immunohistochemical assays using CD34 and CD31 pan-endothelial antibodies.
7p
virose2711
25-09-2020
13
1
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Elevated mammographic density (MD) is a strong breast cancer risk factor but the mechanisms underlying the association are poorly understood. High MD and breast cancer risk may reflect cumulative exposures to factors that promote epithelial cell division.
12p
vimoscow2711
29-08-2020
9
1
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Chromosome 7 open reading frame 24 (C7orf24) was originally identified as a highly expressed protein in various types of cancer, and later shown to be a γ-glutamylcyclotransferase (GGCT). GGCT depletion in cancer cells has anti-proliferative effects in vitro and in vivo, and it is therefore considered a promising candidate as a therapeutic target. However, the cellular events induced by GGCT depletion remain unclear.
9p
vimale2711
25-08-2020
10
2
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Former studies already revealed the anti-neoplastic properties of the anti-infective agent Taurolidine (TRD) against many tumor species in vitro and in vivo. Its anti-proliferative and cell death inducing capacity is largely due to its main derivative Taurultam (TRLT).
13p
vimale2711
21-08-2020
9
1
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The Cancer Genome Atlas Research Network reported that high-grade serous carcinoma (HGSC) can be classified based on gene expression profiles into four subtypes, termed “immunoreactive,” “differentiated,” “proliferative,” and “mesenchymal.”
8p
vidhaka2711
31-07-2020
10
1
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An Eight-month-old intact Male Harlequin Great Dane Dog was presented to Small Animal Surgery Outpatient Unit of Madras Veterinary College with a history of a chronic non-healing wound on the lateral aspect of the distal hock region. Subjective analysis of the wound on the day of presentation revealed pink colour with purulent exudate and offensive odour. A wound planimetry was performed and the wound was dimensionally measured (10cm x12 cm).The wound was highly exudative and was in the inflammatory phase, a wet to dry bandaging was performed on alternate days until the exudates reduced.
5p
caygaocaolon4
04-04-2020
14
2
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In the grand scheme of things, however, even a million-dollar business is not particularly large. Many good regional businesses reach this mark, from home improvement contractors to small law firms. And though it is a worthy goal to have every business flourish as well as it can, our focus here is on startups that could go well beyond a million in annual revenues. These high-growth firms would, at the least, become prominent niche firms of the type described earlier. They would create jobs prolifically and serve global or national markets.
24p
trinhcaidat
19-04-2013
36
2
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Endogenous mono-ADP-ribosylation in eukaryotes is involved in regulating protein synthesis, signal transduction, cytoskeletal integrity, and cell prolifer-ation, although few cellular ADP-ribosyltransferases have been identified. The sirtuins constitute a highly conserved family of protein deacetylases, and several family members have also been reported to perform protein ADP-ribosylation.
18p
vinaphone15
25-02-2013
45
2
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On the 22nd of March, 1819, about nine o'clock in the morning, a young man, some twenty-three or twenty-four years old, wearing the dress of a German student, which consists of a short frock-coat with silk braiding, tight trousers, and high boots, paused upon a little eminence that stands upon the road between Kaiserthal and Mannheim, at about three-quarters of the distance from the former town, and commands a view of the latter. Mannheim is seen rising calm and smiling amid gardens which once were ramparts, and which now surround and embrace it like a girdle of foliage and flowers....
53p
hotmoingay6
23-01-2013
45
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Highly proliferative neuroendocrine carcinoma – influence of radiotherapy fractionation on tumor response...
5p
toshiba10
15-10-2011
44
1
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Hierarchy of hematopoietic differentiation. Stem cells are multipotent cells that are the source of all descendant cells and have the capacity to provide either long-term (measured in years) or short-term (measured in months) cell production. Progenitor cells have a more limited spectrum of cells they can produce and are generally a short-lived, highly proliferative population also known as transient amplifying cells. Precursor cells are cells committed to a single blood cell lineage but with a continued ability to proliferate; they do not have all the features of a fully mature cell.
5p
konheokonmummim
03-12-2010
79
4
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Archimedes and Sons, Inc. is a developer and distributor of science and mathematics training programs aimed at community colleges and technical schools. Rather than provide CD-ROMs, which the technically-adept students tend to copy prolifically for their friends (thereby depriving A & S of their revenue), the firm provides interactive web-based training to user accounts (which are still abused, but less so).
1p
trungha
28-08-2009
79
3
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