Hormone peptide

A complex set of perturbations occur in cytokines and hormones in the etiopathogenesis of obesity and related cardiometabolic conditions such as type 2 diabetes (T2D). Evidence for the genetic regulation of these cytokines and hormones is limited, particularly in African-ancestry populations. In order to improve our understanding of the biology of cardiometabolic traits.

21p vibransone 28-03-2024 2 2   Download

In ebook "Cellular peptide hormone synthesis and secretory pathways" the concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone.

245p tachieuhoa 28-01-2024 6 2   Download

Part 2 book "Blackwell's five-minute veterinary consult - Laboratory tests and diagnostic procedures, canine and feline" includes content: Lupus erythematosus cell preparation, lower urinary tract ultrasonography, luteinizing hormone, lyme disease serology, magnetic resonance imaging, masticatory muscle myositis (2m antibody assay), muscle and nerve biopsy, nasal flush and biopsy, nasolacrimal irrigation, natriuretic peptides, ocular ultrasonography,... and other contents.

399p muasambanhan04 14-01-2024 5 2   Download

Part 1 book "Metabolic and endocrine physiology" includes content: Endocrine system, endocrine secretory control, hormone disposition, measurement and secretion, mechanisms of catecholamine and polypeptide hormone action, steroid and thyroid hormones, hypothalamus and pituitary, proopiomelanocortin and related peptides,... and other contents.

110p oursky07 24-10-2023 7 2   Download

Parathyroid hormone-related peptide (PTHrP) overexpression and poor patient outcome have been reported for many human tumors, but no studies are available in laryngeal cancer. Therefore, we studied the expression of PTHrP and its receptor, parathyroid hormone-related peptide receptor type 1 (PTH1R), in primary locally advanced laryngeal squamous cell carcinomas (LALSCC) also in relation to the clinical outcome of patients.

14p visusanwojcicki 28-06-2022 9 2   Download

The use of salivary biomarkers has garnered attention because the composition of saliva refects the body’s physiological state. Saliva contains a wide range of components, including peptides, nucleic acids, electrolytes, enzymes, and hormones.

9p vidarwin 22-02-2022 10 1   Download

This study aimed to evaluate spexin as a novel blood marker and to describe the relationship of this peptide with selected biochemical metabolites measured during the transition period in dairy cows.

13p vidarwin 22-02-2022 15 1   Download

Various studies have shown that the insulin-like peptides present in insects and investigation of their possible effects on insect physiology have significance for clarifying the evolutionary developmental period of insulin. The insect fat body is an organ analog to vertebrate adipose tissue and liver. In insects which do not have feeding activity during pupal and adult stages such as Bombyx mori, substances and energy required for continuation of life and development of tissues and organs are provided by the fat body via the autophagy process.

10p dolomite36 30-12-2021 17 0   Download

Crustacean hyperglycaemic hormone (CHH) is a neuropeptide that was originally identified in the X-organ/sinus gland complex of the eyestalks (ESs) in crustaceans. Several CHH isoforms and spliced variants were later identified in other tissues, and their functions have still not been completely unveiled. In this study, the identification and characterisation of the conventional CHH prepropeptide from the ESs of the littoral crab, Carcinus aestuarii, via rapid amplification of cDNA ends was reported.

10p dolomite36 30-12-2021 7 0   Download

The microbiota is a heterogeneous ecosystem consisting of diverse microorganisms unique to an individual, playing a crucial role in maintaining human body homeostasis. The microbiota, as a suggested endocrine organ, is also capable of producing and regulating hormones, playing an important role in food processing, synthesis of vitamins, pathogen displacement, and influencing functions of distant systems and organs.

9p lazzaro 30-12-2021 10 0   Download

Nồng độ BNP hay NT-proBNP được biết là gia tăng và là một phương tiện chẩn đoán, tiên lượng trong suy tim. Mục đích nghiên cứu của đề tài nhằm xác định liệu nồng độ NT-proBNP huyết thanh có gia tăng ở bệnh nhân tai biến mạch máu não cấp và có liên quan với mức độ nặng của bệnh hay không.

10p viyeri2711 09-09-2021 14 1   Download

Insulin/insulin-like growth peptide signaling (IIS) down-regulates hemolymph sugar level and facilitates larval growth in the soybean pod borer, Maruca vitrata. The objective of this study is to determine whether IIS of M. vitrata can mediate ovarian development of adult females.

14p viwyoming2711 16-12-2020 8 1   Download

Luteinizing hormone-releasing hormone receptor (LHRHr) represents a promising therapeutic target for treating sex hormone-dependent tumors. We coupled cecropin B, an antimicrobial peptide, to LHRH’, a form of LHRH modified at carboxyl-terminal residues 4–10, which binds to LHRHr without interfering with luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion.

9p vinaypyidaw2711 26-08-2020 12 1   Download

The peptide hormone gastrin exerts a growth-promoting effect in both normal and malignant gastrointestinal tissue. Gastrin mediates its effect via the cholecystokinin 2 receptor (CCKBR/CCK2R). Although a substantial part of the gastric adenocarcinomas express gastrin and CCKBR, the role of gastrin in tumor development is not completely understood.

13p vimale2711 21-08-2020 8 1   Download

Nullomer peptides are the smallest sequences absent from databases of natural proteins. We first began compiling a list of absent 5-amino acid strings in 2006.

10p vidhaka2711 31-07-2020 7 1   Download

In melting flesh peaches, auxin is necessary for system-2 ethylene synthesis and a cross-talk between ethylene and auxin occurs during the ripening process. To elucidate this interaction at the transition from maturation to ripening and the accompanying switch from system-1 to system-2 ethylene biosynthesis.

17p vihashirama2711 21-05-2020 9 0   Download

The commencement of puberty has been interesting topic for reproductive endocrinologists for years. Yet its fundamental physiological mechanisms have stayed mysterious until recently. The findings and understanding of the effects put forth by the peptide hormone kisspeptin have shed light on this research area. Kisspeptin (Kp), a family of neuropeptides which is produced chiefly by neuronal clusters at discrete hypothalamic nuclei, are vital regulators of GnRH neurons.

8p trinhthamhodang5 16-05-2020 10 1   Download

Hepcidin (H25) is a hormone peptide synthesized by the liver that binds to ferroportin and blocks iron export. In this study, H25 was inhibited by administration of single and multiple doses of an anti-H25 monoclonal antibody Ab 12B9m in cynomolgus monkeys. The objective of this analysis was to develop a pharmacodynamic model describing the role of H25 in regulating iron homeostasis and the impact of hepcidin inhibition by Ab 12B9m. Total serum H25 and Ab 12B9m were determined in each animal. Corresponding measurements of serum iron and hemoglobin (Hb) were obtained.

15p caothientrangnguyen 09-05-2020 10 0   Download

Glucagon nasal powder (GNP), a novel intranasal formulation of glucagon being developed to treat insulin-induced severe hypoglycemia, contains synthetic glucagon (10 % w/w), beta-cyclodextrin, and dodecylphosphocholine. The safety of this formulation was evaluated in four studies in animal models.

16p vienzym2711 30-03-2020 16 2   Download

Collagen thủy phân là hỗn hợp các peptide có phân tử lượng nhỏ hơn 20 kDa được thủy phân từ collagen hoặc gelatin bằng enzyme. Nó có những tính chất và hoạt tính sinh học như khả năng chống oxi hóa, chống đông, kháng khuẩn, ngăn chặn tia cực tím và là chất kích thích cho các hormone làm lành bệnh viêm khớp,... mà collagen và gelatin không có được. Vì vậy, collagen thủy phân được ứng dụng rộng rãi trong công nghiệp thực phẩm, mỹ phẩm và dược phẩm.

9p angicungduoc2 02-01-2020 109 8   Download