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Hormone therapy
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Prostate cancer (PCa) is one of the major tumor diseases that threaten men’s health globally, and biochemical recurrence significantly impacts its prognosis. Disulfidptosis, a recently discovered cell death mechanism triggered by intracellular disulfide accumulation leading to membrane rupture, is a new area of research in the context of PCa. Currently, its impact on PCa remains largely unexplored.
12p
vishanshan
27-06-2024
3
1
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This book has four top ten lists to provide even more ways of navigating the changes you'll experience throughout menopause―exposing common myths about menopause, giving you the scoop on medical tests you might need, kicking around ideas to kick-start or rejuvenate your exercise routine, and tempting you with fabulous healthy foods (because eating healthy doesn't have to be boring).
386p
zizaybay1104
29-05-2024
2
2
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There are an estimated 55 million Americans over the age of 50 who have low bone mass. This easy-to-understand guide helps readers assess their risk and find a practical approach to the diagnosis, treatment, and prevention of osteoporosis. It covers bone density tests and a wide range of treatment options for osteoporosis-from hormone replacement therapy and acupuncture to calcium-rich foods, supplements, and exercise-and offers pointers on preventing broken hips and other common fractures.
314p
zizaybay1104
29-05-2024
3
2
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DNA originating from degenerate tumour cells can be detected in the circulation in many tumour types, where it can be used as a marker of disease burden as well as to monitor treatment response. Although circulating tumour DNA (ctDNA) measurement has prognostic/predictive value in metastatic prostate cancer, its utility in localised disease is unknown.
11p
vibransone
28-03-2024
3
2
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Ebook "Q’eqchi’ maya reproductive ethnomedicine" have an extensive pharmacopoeia of medicinal plants used traditionally for reproductive health and fertility, utilizing more than 60 plant species for these health treatments. Ten species were selected for investigation of their estrogenic activity using a reporter gene assay. Nine of the species were estrogenic, four of the species were also antiestrogenic, and two of the extracts were cytotoxic to the MCF-7 breast cancer cell line.
134p
manmanthanhla0201
26-02-2024
2
1
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Ebook "Regenerating the heart: Stem cells and the cardiovascular system" organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies.
555p
tachieuhoa
28-01-2024
4
2
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Despite benefits of endocrine therapy (ET) for patients with hormone-receptor (HR)-positive breast cancer, many patients do not initiate or discontinue ET against recommendations.
12p
vimichaelfaraday
28-12-2023
4
3
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Metastasis-directed therapy (MDT) significantly delays the initiation of palliative androgen deprivation therapy (pADT) in patients with oligorecurrent prostate cancer (PCa) with a positive impact on patient’s quality of life.
10p
vileonardodavinci
23-12-2023
5
2
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Vaginal CO2 laser therapy is a new treatment option for genitourinary syndrome of menopause. Its potential is particularly interesting in breast cancer survivors, where existing treatment options often are insufficient as hormonal treatment is problematic in these women.
7p
vileonardodavinci
23-12-2023
4
2
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The adjuvant treatment with Aromatase Inhibitor (AI) is considered standard of care for postmenopausal breast cancer (BC) women with hormone receptor-positive (HR+), however, it often causes adverse effects such as cancer-related fatigue (CRF).
20p
vialfrednobel
23-12-2023
4
3
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Tamoxifen is one of the fundamental pillars of adjuvant endocrine therapy for hormone receptor-positive breast cancer; however, 30–50% of patients receiving tamoxifen experience tumor relapse. This study aimed at determining the frequencies of the most clinically relevant CYP2D6 alleles and evaluating their impact on the respon‑siveness to tamoxifen in a cohort of Syrian breast cancer patients.
11p
vialfrednobel
23-12-2023
6
3
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Endocrine therapy is frequently administered in patients with hormone dependent (HR+) metastatic endometrial cancer. The aim of this study was to explore the incidence and clinical relevance of circulating ESR1 mutations in patients treated by AI or megestrol acetate (M) for advanced endometrial carcinoma.
9p
vialfrednobel
23-12-2023
4
3
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This paper sought to determine the social issues among adult cancer patients seen at the oncology clinic of Moi Teaching and Referral Hospital (MTRH), Eldoret. Focus was on the social issues that are associated with cancer diagnosis and socio-demographic characteristics and clinical state of the patients diagnosed with cancer.
17p
vikissinger
21-12-2023
4
2
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To determine the frequency of H1047R mutation on exon 20 PIK3CA gene in the plasma of hormone recepter positive (HR+) breast cancer (BC) women and its relationship with clinical characteristics of these patients. Subjects: Plasma was separated from venous blood of 141 female HR+ BC patients, have been treating at 108 Military Central Hospital from June 2021 to June 2023.
9p
vigeorge
06-12-2023
2
2
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Real-world data of Palbociclib are insufficient in China. This study aimed to investigate the treatment pattern and real-world outcomes in hormone receptor positive and human epidermal growth factor 2 receptor negative (HR+/HER2-) metastatic breast cancer (MBC) patients treated with Palbociclib in the northwest of China.
13p
vischultz
20-10-2023
2
1
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This retrospective study explored the relationship between hormone receptor (HR), human epidermal growth factor receptor 2 (HER2) status, and bone involvement in the first distant metastases (DM) of Chinese breast cancer (BC) patients who lacked the HER2 targeted therapy.
9p
vischultz
20-10-2023
3
1
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There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which subsequent treatment oncologists prefer in patients with disease progression under CDKi.
10p
vischultz
20-10-2023
2
1
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Previous studies reported inconsistent results regarding the association between keratinocyte carcinoma (KC) and exogenous hormone therapy. This study aimed to investigate the association between the use of exogenous sex hormones and the risk of KC among women.
8p
visharma
20-10-2023
2
2
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Extending adjuvant endocrine therapy (ET) beyond the standard 5 years ofers added protection against late breast cancer recurrences in women with early-stage hormone receptor-positive (HR+) breast cancer. Little is known about treatment persistence to extended ET (EET) and the role that genomic assays may play. In this study, we evaluated persistence to EET in women who had Breast Cancer Index (BCI) testing.
9p
vioracle
29-09-2023
4
2
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Precise prognostication is the key to optimum and effective treatment planning for early-stage hormone receptor (HR) positive, HER2/neu negative breast cancer patients. Differences in the breast cancer incidence and tumor anatomical features at diagnosis, pharmacogenomics data between Western and Indian women along with the vast diversity in the economic status and differences in insurance policies of these regions.
11p
vioracle
29-09-2023
2
2
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