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HPV E6 protein
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Oncogenic Human Papillomaviruses (HPVs) base their transforming potential on the action of both E6 and E7 viral oncoproteins, which perform cooperative or antagonistic actions and thus interfere with a variety of relevant cellular targets.
13p
vialfrednobel
23-12-2023
5
3
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Bài viết Tiềm năng ức chế protein E6 của virus HPV của các hợp chất flavon thông qua mô phỏng máy tính hướng đến việc sàng lọc các hợp chất có trong các cây thuốc tự nhiên, một nguồn tài nguyên phong phú của nước ta để tìm ra hợp chất có khả năng gắn kết tốt trên protein E6, dẫn đến việc ức chế E6 trong điều trị ung thư cổ tử cung.
8p
vihawkeye
02-06-2023
5
4
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MicroRNAs have emerged as an important regulator of cell cycle and various other cellular processes. Aberration in microRNAs has been linked with development of several cancers and other diseases but still very little is known about the mechanism by which they regulate these cellular events.
11p
vikolindagrabar
27-07-2022
4
1
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The high risk Human Papillomavirus (HPV) E6 oncoproteins play an essential role in the development of cervical malignancy. Important cellular targets of E6 include p53 and the PDZ domain containing substrates such as hScrib and Dlg. We recently showed that hScrib activity was mediated in part through recruitment of protein phosphatase 1γ (PP1γ).
9p
vialabama2711
21-09-2020
13
0
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High-risk human papillomaviruses (HPVs) are strongly associated with the development of some malignancies. The E6 and E7 viral oncoproteins are the primary proteins responsible for cell homeostasis alteration and immortalization.
8p
vimale2711
25-08-2020
8
1
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Persistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins.
13p
viorochimaru2711
01-06-2020
11
1
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