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Human hepatocellular carcinomas
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Long nonconding RNAs (lncRNAs) have been found to be a vital regulatory factor in the development process of human cancer, and could regarded as diagnostic or prognostic biomarkers for human cancers. Here, we aim to confirm the expression and molecular mechanism of RP11-171K16.5 (lnc171) in hepatocellular carcinoma (HCC).
13p
vishanshan
27-06-2024
1
1
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This study endeavors to evaluate the safety, efficacy, and prognostic impacts of employing hepatic arterial infusion chemotherapy (HAIC), lenvatinib, and humanized programmed death receptor-1 (PD-1) in the treatment of high-risk HCC patients.
11p
vishanshan
27-06-2024
1
1
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Tumor-associated macrophages (TAMs) constitute a substantial part of human hepatocellular carcinoma (HCC). The present study was devised to explore TAM diversity and their roles in HCC progression.
16p
vikoch
27-06-2024
1
1
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In addition, their inhibitory activity on NO production and cytotoxic effects against human embryonic kidney cells (HEK-293A) and human hepatocellular carcinoma (HepG2) were evaluated. This is the first study of the phytochemical investigation of P. ginseng sprouts cultivated in Vietnam and ginseng sprouts also contained the same main active ginsenosides as in the 4–6-year old roots.
7p
dianmotminh02
03-05-2024
4
1
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Hepatocellular carcinoma (HCC) is a common primary liver cancer with poor overall survival. We hypothesized that there are HCC-associated cell-types that impact patient survival. We combined liver single nucleus (snRNA-seq), single cell (scRNA-seq), and bulk RNA-sequencing (RNAseq) data to search for cell-type differences in HCC.
20p
viellison
28-03-2024
3
2
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Ebook "Mycotoxins and their metabolites in humans and animals" summarizes the results of publications dealing with the natural and artificial contamination of humans and animals by mycotoxins, as well as mycotoxin experiments with animals. The major part of the book lists animal studies that investigate deposits and elimination of these toxic fungal metabolites. Furthermore, the results of articles documenting mycotoxin contamination of pets are also presented.
526p
manmanthanhla0201
26-02-2024
3
1
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The incidence of primary liver tumors, hepatocellular carcinoma (HCC), intrahepatic cholangiocellular carcinoma (ICC), and combined HCC/ICC (cHCC/CC) is increasing. For ICC, targeted therapy exists only for a small subpopulation of patients, while for HCC, Sorafenib and Lenvatinib are in use.
11p
vileonardodavinci
23-12-2023
5
2
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Acid phosphatase type 6 (ACP6) is a mitochondrial lipid phosphate phosphatase that played a role in regulating lipid metabolism and there is still blank in the clinico-pathological significance and functional roles of ACP6 in human cancers. No investigations have been conducted on ACP6 in hepatocellular carcinoma (HCC) up to date.
14p
vileonardodavinci
23-12-2023
8
3
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In our previous study, N end of the Circumsporozoite protein (CSP I-plus) modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed, which had antiangiogenic capability and bound to hepatocellular carcinoma in vivo and in vitro. In this study, the inhibition of rES-CSP on hepatocellular carcinoma metastasis was verified in vivo and in vitro, and its possible mechanism was explored.
12p
vileonardodavinci
23-12-2023
3
2
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Dopamine receptors have been reported to play important roles in cancer progression. However, the role of dopamine receptor D3 (DRD3) in hepatocellular carcinoma (HCC) remains unclear.
15p
vileonardodavinci
23-12-2023
6
2
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The Wnt/β-catenin signaling pathway plays an important role in embryogenesis and tumorigenesis. In human cancer, abnormal activity of Wnt/β-catenin signaling pathway induces overexpressed of downstream genes, and initiate oncogene.
17p
vileonardodavinci
23-12-2023
6
2
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The aim of this study was to investigate the interrelationships among PKC isoforms, telomerase and AFP in HCC. PKCα and PKCδ were the most expressed isoforms in HepG2/C3A, PLC/PRF/5, SNU-387 and SKOV-3 cells.
17p
vikissinger
21-12-2023
1
1
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The global burden of hepatocellular carcinoma (HCC) is increasing, negatively impacting social health and economies. The discovery of novel and valuable biomarkers for the early diagnosis and therapeutic guidance of HCC is urgently needed.
18p
vialfrednobel
23-12-2023
4
3
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The study aimed to investigate the over expression of IFITM3 in hepatocellular carcinoma Egyptian patients. Background Hepatocellular carcinoma (HCC) continues to be a serious disease burden. Interferon Induced Transmembrane protein 3 (IFITM3) is a protein that encoded in humans by the IFITM3 gene.
7p
visharma
20-10-2023
2
2
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This study aimed to identify the biological functions, expression modes, and possible mechanisms underlying the relationship between metastatic human hepatocellular carcinoma (HCC) and MicroRNA-188-5p (miR188) dysregulation using cell lines.
13p
visharma
20-10-2023
2
2
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Selenium metabolism has been implicated in human health. This study aimed to identify a selenium metabolism regulator-based prognostic signature for hepatocellular carcinoma (HCC) and validate the role of INMT in HCC.
17p
visharma
20-10-2023
5
3
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Hepatocellular carcinoma (HCC) is one of the most common human cancers with poor prognosis in the world. HCC has become the second leading cause of cancer-related death in China. It is urgent to identify novel biomarker and valid target to effectively diagnose, treat or predict the prognosis of HCC.
17p
vioracle
29-09-2023
2
2
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Reportedly, circular RNA (circRNA) is a key modulator in the development of human malignancies. This work is aimed to probe the expression pattern, biological effects and mechanism of circ_0064288 on hepatocellular carcinoma (HCC) progression.
11p
vikolindagrabar
27-07-2022
3
1
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Immunotherapy has become a new therapy for advanced hepatocellular carcinoma (HCC); however, its treatment results are considerably different. CD4+ T cells (CD4+) are the key to immunotherapy, but patients with HCC that have low CD4+ are rarely observed for clinical evidence.
10p
vikolindagrabar
27-07-2022
3
1
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Liver cancer is a major global health concern due to the steady increases in its incidence and mortality. Transcription factors, yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1, also known as TAZ) have emerged as critical regulators in human hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), the two major types of primary liver cancer.
11p
vikolindagrabar
27-07-2022
4
2
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