Human liver
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This compassionate guide explains how hepatitis C affects the liver and the body and provides solid advice on today's treatment options-from drugs (and their side effects) to transplants and alternative therapies-as well as tips on dealing with the emotional and financial burdens the disease brings with it. Nina L Paul, PhD (New York, NY) earned her doctorate in infectious disease epidemiology and immunology from Yale University. She has researched viruses (human immunodeficiency virus and others) and the immune system.
314p zizaybay1104 29-05-2024 2 2 Download
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Part 1 book "Netter’s illustrated human pathology" includes content: General reaction patterns; cardiovascular system; respiratory system; gastrointestinal system; liver, gallbladder, and pancreas.
200p zizaybay1101 30-04-2024 4 2 Download
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Viral and bacterial infections are involved in the development of human cancers, such as liver, nasopharyngeal, cervical, head and neck, and gastric cancers. Aberrant DNA methylation is frequently present in these cancers, and some of the aberrantly methylated genes are causally involved in cancer development and progression.
13p vioraclene 31-03-2024 2 2 Download
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Hepatic fibrosis is the underlying cause of cirrhosis and liver failure in nearly every form of chronic liver disease, and hepatic stellate cells (HSCs) are the primary cell type responsible for fibrosis. Long noncoding RNAs (lncRNAs) are increasingly recognized as regulators of development and disease; however, little is known about their expression in human HSCs and their function in hepatic fibrosis.
20p vioraclene 31-03-2024 7 2 Download
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Hepatocellular carcinoma (HCC) is a common primary liver cancer with poor overall survival. We hypothesized that there are HCC-associated cell-types that impact patient survival. We combined liver single nucleus (snRNA-seq), single cell (scRNA-seq), and bulk RNA-sequencing (RNAseq) data to search for cell-type differences in HCC.
20p viellison 28-03-2024 3 2 Download
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Gastrointestinal cancers, including liver cancer, colorectal cancer, and stomach cancer, are the most common cancers in the world as well as in Vietnam, posing a leading threat to human health. The cost of treating these cancers is a major problem that burdens not only patients but also healthcare systems. The study aims to analyze treatment costs for the four most common types of gastrointestinal cancer nowadays.
9p vilarry 12-03-2024 2 2 Download
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The incidence of primary liver tumors, hepatocellular carcinoma (HCC), intrahepatic cholangiocellular carcinoma (ICC), and combined HCC/ICC (cHCC/CC) is increasing. For ICC, targeted therapy exists only for a small subpopulation of patients, while for HCC, Sorafenib and Lenvatinib are in use.
11p vileonardodavinci 23-12-2023 5 2 Download
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In our previous study, N end of the Circumsporozoite protein (CSP I-plus) modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed, which had antiangiogenic capability and bound to hepatocellular carcinoma in vivo and in vitro. In this study, the inhibition of rES-CSP on hepatocellular carcinoma metastasis was verified in vivo and in vitro, and its possible mechanism was explored.
12p vileonardodavinci 23-12-2023 3 2 Download
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Methotrexate (MTX) is a chemotherapy and immunosuppressive agent widely used to treat cancer, autoimmune diseases in children and adult patients, and ectopic pregnancy. However, MTX is highly toxic to the liver, kidney, and nervous system. This study aimed to quantify the concentration of MTX in human plasma using high-performance liquid chromatography (HPLC).
6p vikissinger 21-12-2023 1 1 Download
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The mammalian target of rapamycin (mTOR) kinase, a central component of the PI3K/AKT/mTOR pathway, plays a critical role in tumor biology as an attractive therapeutic target. We conducted this first-in-human study to investigate the safety, pharmacokinetics (PK), and pilot efficacy of LXI-15029, an mTORC1/2 dual inhibitor, in Chinese patients with advanced malignant solid tumors.
12p vialfrednobel 23-12-2023 2 2 Download
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Part 1 book "Comparative hepatitis" includes content: Hepatitis in the clinics — Treatment options, differential diagnosis of human hepatitis, comparative pathology, hepatitis B virus - Lessons learned from the virus life cycle, chronic hepatitis C - Portrait of a silent epidemic and the etiologic agent, hepatitis A infection, hepatitis E infection, bacterial infections of the liver.
171p muasambanhan01 13-12-2023 2 1 Download
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Part 2 book "Comparative hepatitis" includes content: Comparative hepatitis - Diseases caused by adult parasites or their distinct life cycle stages, autoimmune hepatitis in humans, hepatitis in dogs, hepatitis in horses, the woodchuck model of hepadnavirus infection, hepadnaviruses have a narrow host range — do they, the liver as immune escape site for pathogens, drug candidates for the treatment of viral hepatitis.
219p muasambanhan01 13-12-2023 3 1 Download
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Polyphyllin I (PPI) is a naturally active steroidal saponin that has good therapeutic effects in various cancers, such as liver and lung cancers. However, owing to its non-selective distribution in various tissues, it is toxic and has side effects on normal human organs while taking effect.
12p viberbers 09-08-2023 3 2 Download
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Cholangiopathy in acquired immune deficiency syndrome (AIDS) is being less frequently reported since antiretroviral therapy (ART) is available. It is associated with an advanced disease and seen in situations with poor access or non-compliance with ART. Liver biopsy is thought to have low yield in cases of AIDS cholangiopathy, but it can be an important tool in diagnosis, especially early in the course of the disease.
9p viwhitewolf 03-07-2023 7 2 Download
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Ebook "Metabolism of human diseases: Organ physiology and pathophysiology" examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The book also describes commonly used drugs and explains their molecular targets.
382p tukhongthienlac 24-06-2023 11 3 Download
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RAD140 (Testalone) is a novel selective androgen receptor modulator with very limited data currently available on adverse effects related to this compound. The first-in-human phase 1 trial was recently published and did report a significant proportion of elevated aspartate aminotransferase, alanine transaminase, and total bilirubin among the test subjects.
3p vidoctorstrange 06-05-2023 5 2 Download
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Vibrio vulnificus is typically present in seawater, fsh, and shellfish, and is known to cause severe sepsis, particularly in patients with liver diseases such as cirrhosis. V. vulnificus is one of the most dangerous waterborne pathogens, and infection mainly occurs in western Japan during the summer, with an increased fatality rate.
5p videadpool 05-05-2023 6 2 Download
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Over the last two decades, several cases of infections caused by Lactococcus lactis have been reported. This Gram-positive coccus is considered non-pathogenic for humans. However, in some rare cases, it can cause serious infections such as endocarditis, peritonitis, and intra-abdominal infections.
8p videadpool 05-05-2023 7 2 Download
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Previously, it was shown that the HFE gene (associated with human hereditary hemochromatosis) has several haplotypes of intronic polymorphisms. Some haplotype frequencies are race specific and hence can be used in phylogenetic analysis.
13p vinarcissa 21-03-2023 2 1 Download
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Liver cancer is a major global health concern due to the steady increases in its incidence and mortality. Transcription factors, yes-associated protein (YAP) and WW domain-containing transcription regulator protein 1 (WWTR1, also known as TAZ) have emerged as critical regulators in human hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), the two major types of primary liver cancer.
11p vikolindagrabar 27-07-2022 4 2 Download