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Hypothesis generation
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Ebook "The evolution of molecular biology: The search for the secrets of life" provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds.
244p
lucchinguyen
28-12-2023
9
3
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With the availability of health insurance claim data, pharmacovigilance for various drugs has been suggested; however, it is necessary to establish an appropriate analysis method. To detect unintended drug effects and to generate new hypotheses, we conducted a hypothesis-free study to systematically examine the relationship between all prescription nonanticancer drugs and the mortality of colorectal cancer patients.
11p
vioracle
29-09-2023
6
2
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Part 1 of ebook "The psychology of closed mindedness" provides readers with contents including: motivational bases of closed and open mindedness; specific manifestations of closure needs in information processing activites; prior psychological analyses of closed and open mindedness; intrapersonal effects of closure needs;...
103p
thamnhuocgiai
24-09-2023
4
2
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Although omics datasets represent valuable assets for hypothesis generation, model testing, and data validation, the infrastructure supporting their reuse lacks organization and consistency. Using nuclear receptor signaling transcriptomic datasets as proof of principle, we developed a model to improve the discoverability, accessibility, and citability of published omics datasets.
6p
visteverogers
24-06-2023
3
2
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Demonstrate how observational causal inference methods can generate insights into the impact of chronic disease combinations on patients’ 30-day hospital readmissions. Multi-hypothesis causal analysis, a new methodological tool, generates meaningful insights from health care claims data, guiding the design of care and intervention programs.
9p
visteverogers
24-06-2023
5
2
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Microcirculatory driving pressure is defined as the difference between post-arteriolar and venular pressure. In previous research, an absence of correlation between mean arterial blood pressure (MAP) and microcirculatory perfusion has been observed. However, the microcirculation may be considered as a low pressure compartment with capillary pressure closer to venous than to arterial pressure.
7p
viisaacnewton
26-04-2022
9
1
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The recent global financial crisis and the subsequent sovereign debt crisis of the Eurozone peripheral countries have generated historic levels of volatility and instability in the financial markets. In particular, during the sovereign debt crisis market operators have begun to focus on the so-called “redenomination risk”, that is the hypothesis of exit from the EMU (Euro Monetary Union) by one or more countries and the consequent redenomination of their debt in the past national currency.
30p
nat_qb73
21-02-2021
15
2
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Gene Ontology (GO) enrichment analysis remains one of the most common methods for hypothesis generation from high throughput datasets. However, we believe that researchers strive to test other hypotheses that fall outside of GO. Here, we developed and evaluated a tool for hypothesis generation from gene or protein lists using ontological concepts present in manually curated text that describes those genes and proteins.
10p
viwyoming2711
16-12-2020
16
1
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Performing a statistical test requires a null hypothesis. In cancer genomics, a key challenge is the fast generation of accurate somatic mutational landscapes that can be used as a realistic null hypothesis for making biological discoveries.
10p
vicolorado2711
22-10-2020
11
1
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The use of imaging to implement on-treatment adaptation of radiotherapy is a promising paradigm but current data on imaging changes during radiotherapy is limited. This is a hypothesis-generating pilot study to examine the changes on multi-modality anatomic and functional imaging during (chemo)radiotherapy treatment for head and neck squamous cell carcinoma (HNSCC).
11p
vialabama2711
21-09-2020
15
0
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BRCA1/2 germline mutation related cancers are candidates for new immune therapeutic interventions. This study was a hypothesis generating exploration of genomic data collected at diagnosis for 19 patients.
16p
vijakarta2711
09-06-2020
7
1
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This paper shows that most admired companies generate admirable stock performance relative to the market. The current study analyses risk premiums and risk-adjusted excess returns of a portfolio of firms ranked as the most admired companies in the United States from 2006 to 2011. The results show that average risk premiums of an equal-weighted portfolio of most admired firms are economically superior than the market risk premiums from 2006 to 2011 (except 2010).
9p
nguyenminhlong19
21-04-2020
15
2
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This study aims to determine the management practices of the banking Industry in the Kingdom of Bahrain and their level of effectiveness. The researcher used the qualitative and quantitative type of research in the analysis of data. The survey questionnaire was the main research instrument used by the researcher in generating the primary data of the present study.
12p
035522894
13-04-2020
16
2
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Most clinical trials of antipsychotics in children are brief, failing to address their long-term safety, particularly when taken concurrently with other psychotropics. This hypothesis-generating analysis evaluates potential correlates of weight gain in children receiving extended risperidone treatment.
11p
viamsterdam2711
07-01-2020
13
2
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The paper present: method for detecting anomalous domain names, with focus on algorithmically generated domain names which are frequently associated with malicious activities such as fast flux service networks, particularly for bot networks (or botnets), malware, and phishing. Our method is based on learning a (null hypothesis) probability model based on a large set of domain names that have been white listed by some reliable authority.
11p
kethamoi1
17-11-2019
19
0
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In this paper, we explored the research question: Does Twitter in a large-lecture format university course produced a difference in levels of selfreported student engagement? To do so, we utilize a quasi-experimental design testing the effect of Twitter on student engagement in introductory sociology and anthropology courses. Our hypotheses predicted that students using Twitter would report higher levels of five forms of student engagement (academic, intellectual, peer, and beyond-class engagement, along with an overall engagement variable).
21p
ketaucho
06-11-2019
36
1
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In this paper we work from the algebraic point of view. From now on we do not need any hypothesis on the field k. In this paper we give a condition that implies that the minimal number of generators of the defining ideal I is bounded explicitly by its type.
13p
danhdanh27
08-01-2019
27
2
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We present a cost-based (or energy-based) model of disambiguation. When a sentence is ambiguous, a parse with the least cost is chosen from among multiple hypotheses. Each hypothesis is assigned a cost which is added when: (1) a new instance is created to satisfy reference success, (2) links between instances are created or removed to satisfy constraints on concept sequences, and (3) a concept node with insufficient priming is used for further processing.
8p
buncha_1
08-05-2013
34
1
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This paper describes a novel method for computing a consensus translation from the outputs of multiple machine translation (MT) systems. The outputs are combined and a possibly new translation hypothesis can be generated. Similarly to the well-established ROVER approach of (Fiscus, 1997) for combining speech recognition hypotheses, the consensus translation is computed by voting on a confusion network.
8p
bunthai_1
06-05-2013
45
1
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Báo cáo khoa học: "A Comparative Study on Reordering Constraints in Statistical Machine Translation"
In statistical machine translation, the generation of a translation hypothesis is computationally expensive. If arbitrary wordreorderings are permitted, the search problem is NP-hard. On the other hand, if we restrict the possible word-reorderings in an appropriate way, we obtain a polynomial-time search algorithm. In this paper, we compare two different reordering constraints, namely the ITG constraints and the IBM constraints.
8p
bunbo_1
17-04-2013
39
3
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