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IGF1 gene
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A previous genome-wide association study deduced that one (ARS-BFGL-NGS-39328), two (Hapmap26001-BTC-038813 and Hapmap31284-BTC-039204), two (Hapmap26001-BTC-038813 and BTB-00246150), and one (Hapmap50366-BTA-46960) genome-wide significant single nucleotide polymorphisms (SNPs) associated with milk fatty acids were close to or within the fatty acid synthase (FASN), peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A), ATP-binding cassette, sub-family G, member 2 (ABCG2) and insulin-like growth factor 1 (IGF1) genes.
16p
vinarcissa
21-03-2023
3
1
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Resistance to platinum-based chemotherapy remains a major impediment in the treatment of serous epithelial ovarian cancer. The objective of this study was to use gene expression profiling to delineate major deregulated pathways and biomarkers associated with the development of intrinsic chemotherapy resistance upon exposure to standard first-line therapy for ovarian cancer.
11p
vijennie2711
29-09-2020
16
1
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Genes involved in the IGF-1 aging pathways in the human ovary can be considered strong candidates for predictors of the natural menopause timing. This study evaluates the association between a cytosine-adenine (CA) microsatellite polymorphism in the IGF1 gene promoter P1 and age at natural menopause.
10p
viankara2711
04-12-2019
24
0
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Chromosome 12q23-q24 has been linked to triglyceride (TG) levels by previous linkage studies, and it contains the Insulin-like growth factor 1 (IGF1) gene. We investigated the association between IGF1 and TG levels using two independent samples collected in Taiwan.
8p
vihasaki2711
12-11-2019
16
0
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Teleosts possess a variety of mechanisms for sex determination and differentiation. Sex steroids and temperature play an important role in the regulation of sex gonadal differentiation. Patterns of gene-initiated sexual differentiation are diverse, and species may or may not exhibit sexual dimorphic expression depending on spacing and timing of gene expression, organs, species and stage of fi sh.
9p
advanger2
06-05-2018
33
0
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