Immune manipulation

There are fundamental differences between humans and the animals we typically use to study the immune system. We have learned much from genetically manipulated and inbred animal models, but instances in which these findings have been successfully translated to human immunity have been rare.

14p vibransone 28-03-2024 4 1   Download

Part 2 book "Disease in wild animals, investigation and management" includes content: Disease management through manipulation of the host population, disease management through treatment and immunization, disease management through environmental modification, disease management through influencing human activities, emergency and integrated management programs, assessing the effectiveness of a disease-management program.

173p oursky10 04-12-2023 8 3   Download

Surgery-induced neuroinflammation plays an important role in postoperative cognitive dysfunction (POCD). Gut microbiota is a key regulator of neurological inflammation. Nurturing with prebiotics is an effective microbiota manipulation that can regulate host immunity and cognition.

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The phytopatogen Claviceps paspali is the causal agent of Ergot disease in Paspalum spp., which includes highly productive forage grasses such as P. dilatatum. This disease impacts dairy and beef production by affecting seed quality and producing mycotoxins that can affect performance in feeding animals. The molecular basis of pathogenicity of C. paspali remains unknown, which makes it more difficult to find solutions for this problem. Secreted proteins are related to fungi virulence and can manipulate plant immunity acting on different subcellular localizations.

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Plant transcription factors (TFs) are key transcriptional regulators to manipulate the regulatory network of host immunity. However, the globally transcriptional reprogramming of plant TF families in response to pathogens, especially between the resistant and susceptible host plants, remains largely unknown.

14p vijichea2711 28-05-2021 12 1   Download

Plants are exposed to various types of pathogens and pests throughout their life including viruses, bacteria, fungi, oomycetes, nematodes and insects. Plants have evolved for different strategies to combat pathogen entry and disease development. Pathogenic microorganisms have their own strategies to overcome plant defense responses. Pathogens secrete ‘effector’ molecules which manipulate host cell structure and function to facilitate successful infection and also trigger defense responses in host cells. New emerging concept of ‘effector’ has been put forth in this review.

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Air temperature and relative humidity are two primary environmental factors in terms of THI that determining the heat stress level in livestock. Heat stress has detrimental effects on egg production, egg quality of laying hen and reduced growth rate in broiler production. Exposure of environmental stress during the growing period of broilers has been coupled with undesirable meat quality. Heat stress has adverse effects on behaviour, welfare and immunity of poultry and decreases the egg production resulting in massive economic losses of farmer.

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The increase in the human population in addition to the massive demand for protein of animal origin forced the authorities to seek for additional sources of feed supplies. Aquaculture is the world worth coming expansion to compensate the shortage in animal protein. Feed in aquaculture plays an important role in the production cycle and exert threshold on both practical and economic aspects. Feed additive sectors are expanding day after day to achieve better growth and health for fish and shrimp and to meet the potential requirements of the culturists.

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(BQ) Continued part 1, part 2 of the document Biology and immuno (Ninth edition) has contents: The mucosal immune system, manipulation of the immune response, autoimmunity and transplantation, failures of host defense mechanisms, allergy and allergic diseases,... and other contents. Invite you to refer.

0p thuongdanguyetan06 06-06-2019 20 1   Download

part 1 book “essentials of clinical immunology” has contents: basic components - structure and function, infection, immunodeficiency, anaphylaxis and allergy, autoimmunity, lymphoproliferative disorders, immune manipulation, transplantation, kidney diseases.

187p tieu_vu13 06-08-2018 32 3   Download

The main use of the Oracle database system is to store and retrieve data for applica- tions. The features of the Oracle database and related products described in this sec- tion are used to create applications. We’ve divided the discussion in this section into two categories: database programming and database extensibility options. Later in this chapter, we describe the Oracle Developer Suite, a set of optional tools used in Oracle Database Server and Oracle Application Server development.

65p nhacsihuytuan 13-04-2013 49 3   Download

The “tarp” paintings, made between 1986 and 1988, use tarpaulins for supports that previously covered army trucks. They are stretched and then painted or treated in some way by the artist. The random nature of the patterning caused by the wear to the tarpaulin provides the artist with a point of departure. It avoids the conscious or unconscious decision of where to put the holes, plates or antlers and how to manipulate the shape of the underlying support, because the tarpaulin has already been used.

13p yasuyidol 01-04-2013 46 7   Download

Microbial pathogens exploit the ubiquitin system to facilitate infection and manipulate the immune responses of the host. In this study, susceptibility to Yersinia enterocolitica and Yersinia pseudotuberculosis invasion was found to be increased upon overexpression of the deubiquitinating enzyme otubain 1 (OTUB1), a member of the ovarian tumour domain-containing protein family.

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A variety of microbes manipulate the cytoskeleton of mammalian cells to promote their internalization, motility and⁄or spread. Among such bacte-ria, enteropathogenic Escherichia coliand enterohemorrhagic Escherichia coliare closely related pathogens that adhere to human intestinal cells and reorganize the underlying actin cytoskeleton into ‘pedestals’.

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RNA interference (RNAi) has been regarded as a revolutionary tool for manipulating target biological processes as well as an emerging and prom-ising therapeutic strategy. In contrast to the tangible and obvious effective-ness of RNAiin vitro, silencing target gene expression in vivo using small interfering RNA (siRNA) has been a very challenging task due to multiscale barriers

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Immune system is composed of innate and adaptive responses and plays critical roles in cancer development and destruction. A century ago, Paul Ehrlich postulated that cancer would be quite common in long-lived organisms if not for the protective effects of immunity. About 50 years later, Burnet and Thomas proposed the concept of cancer immunosurveillance based on the experimental evidence of immune recognition of tumor antigens expressed on tumor cells (Dunn et al. 2004 ) . In 1971, the US Congress created a National Cancer Act – a War on Cancer.

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The evidence so far indicates a persistent pattern of lunar-cycle effects in U.S. and international stock returns. However, the combination of high standard deviation of daily returns and relatively short time series results in insufficient statistical significance at the individual stock index level. In Panel B of Table 5 we use the cross-section of international stock data to offer more powerful tests of the lunar cycle effect. Specifically, in the first part of Panel B we pool all data for the G-7 countries together and compute the same statistics.

59p bocapchetnguoi 06-12-2012 67 0   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Feeling manipulated: cytomegalovirus immune manipulation

20p dauphong5 25-12-2011 33 4   Download

Tham khảo luận văn - đề án 'báo cáo y học: " always one step ahead: how pathogenic bacteria use the type iii secretion system to manipulate the intestinal mucosal immune system"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

10p thulanh27 12-12-2011 75 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system...

10p thulanh26 09-12-2011 53 3   Download