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Immunological infiltrate
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PD-L1 showed abnormal mRNA and protein expression in a variety of cancers and predicted prognosis in cancer patients. Furthermore, across a variety of cancer types, the aberrant PD-L1 expression was connected to the MSI, MMR, TMB, drug sensitivity, and tumor immune microenvironment (TIME). Moreover, PD-L1 was significantly correlated with infiltrating levels of immune cells (T cell CD8+, neutrophil, and so on).
19p
vishanshan
27-06-2024
1
1
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Part 1 book "Cancer immunology and immunotherapy" includes content: Immune infiltration in human cancer - prognostic significance and disease control, subversion and coercion - the art of redirecting tumor immune surveillance, a target to enhance antitumor immune response, biology and clinical observations of regulatory T-cells in cancer immunology, concepts and ways to amplify the antitumor immune response, angiogenesis and the tumor vasculature as antitumor immune modulators - The role of vascular endothelial growth factor and endothelin.
163p
muasambanhan08
23-02-2024
6
1
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Thyroid cancer (THCA) has become increasingly common in recent decades, and women are three to four times more likely to develop it than men. Evidence shows that estrogen has a significant impact on THCA proliferation and growth. Nevertheless, the effects of estrogen-related genes (ERGs) on THCA stages, immunological infiltration, and treatment susceptibility have not been well explored.
20p
vialfrednobel
23-12-2023
3
2
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As a highly heterogeneous cancer, the prognostic stratification and personalized management of hepatocellular carcinoma (HCC) are still challenging. Recently, Antigen-presenting-cells (APCs) and T-cells-infiltration (TCI) have been reported to be implicated in modifying immunology in HCC.
16p
vischultz
20-10-2023
2
1
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Leukocyte immunoglobulin-like receptor subfamily B1 (LILRB1) is regarded as an inhibitory molecule. However, the importance of LILRB1 expression in glioma has not yet been determined. This investigation examined the immunological signature, clinicopathological importance and prognostic value of LILRB1 expression in glioma.
21p
visharma
20-10-2023
7
3
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Glioblastoma (GBM) is considered the most malignant and devastating intracranial tumor without effective treatment. Autophagy, apoptosis, and necrosis, three classically known cell death pathways, can provide novel clinical and immunological insights, which may assist in designing personalized therapeutics.
21p
vikolindagrabar
27-07-2022
7
1
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Tubulin alpha-1c chain (TUBA1C), a subtype of α-tubulin, has been shown to be involved in cell proliferation and cell cycle progression in several cancers and to influence cancer development and prognosis. However, a pancancer analysis of TUBA1C to reveal its immunological and prognostic roles has not been performed.
21p
vikolindagrabar
27-07-2022
4
1
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This study intends to investigate the immunological effects of tumor ablation with irreversible electroporation (IRE). Methods: We evaluated the systemic immune response in patients with hepatocellular carcinoma (HCC) after IRE treatment. Furthermore, we analyzed the tumor infiltrating T lymphocytes and the level of serum cytokines in IRE and control groups of tumor-bearing mice.
12p
vianrose2711
27-04-2021
7
1
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RNA sequencing has become a ubiquitous technology used throughout life sciences as an effective method of measuring RNA abundance quantitatively in tissues and cells. The increase in use of RNA-seq technology has led to the continuous development of new tools for every step of analysis from alignment to downstream pathway analysis.
14p
viconnecticut2711
28-10-2020
19
1
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Breast cancer is the most frequently diagnosed cancer in women. Resident macrophages at distant sites provide a highly responsive and immunologically dynamic innate immune response against foreign infiltrates.
12p
vimale2711
21-08-2020
12
2
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Immune escape is an immunological mechanism underlying tumorigenesis, and T cells play an important role in this process. In this study, immune-related genes were evaluated in tumor-infiltrating CD4+ and CD8+ T cells in colon cancer.
11p
vimanila2711
25-06-2020
7
1
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The details of the immunological microenvironment and its clinical implications for pancreatic cancer are still unclear. In this study, we obtained data from public databases, such as the Gene Expression Omnibus, the Cancer Genome Atlas Program, the International Cancer Genome Consortium Data Portal, the ArrayExpress Data Warehouse, and the cBioPortal for Cancer Genomics. We used these data to evaluate the pattern of immune cells infiltration in pancreatic ductal adenocarcinoma (PDAC) tissues.
10p
partimesinhvien
08-05-2020
13
0
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Patients and study design: The study was performed on randomly selected 50 pulmonary tuberculosis patients (mean age, 45.3 ± 3.8, 28 men and 22 women) who had been admitted to the Beijing Tuberculosis and Thoracic Tumor Research Institute during 12 months (April 2008 - April 2009). Pulmonary tuberculosis was diagnosed by the clinical parameters: presence of cough/expectoration, chest X-ray showing infiltrated and /or cavities, a minimum of one positive sputum smear and culture result for acid-fast bacilli.
6p
taisaocothedung
12-01-2013
51
2
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